Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Suman Pokhrel"'
Publikováno v:
KONA Powder and Particle Journal, Vol advpub, Iss 0 (2024)
Custom-made nanomaterials are indispensable in the production of high-value goods in almost any industry. For many applications, materials with defined functional contacts on the nanoscale between different components are crucial. In heterogeneous ca
Externí odkaz:
https://doaj.org/article/c912cff372054b228885693ea9c509a0
Autor:
Luis Rios, Suman Pokhrel, Sin-Jin Li, Gwangbeom Heo, Bereketeab Haileselassie, Daria Mochly-Rosen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The large cytosolic GTPase, dynamin-related protein 1 (Drp1), mediates both physiological and pathological mitochondrial fission. Cell stress triggers Drp1 binding to mitochondrial Fis1 and subsequently, mitochondrial fragmentation, ROS prod
Externí odkaz:
https://doaj.org/article/8067fdebdbc2477ca2f4060fcace8ed0
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The development of direct-acting antivirals to combat COVID-19 remains an important goal. Here the authors design covalent inhibitors that target the papain-like protease from SARS-CoV-2. The most promising inhibitor blocks viral replication in mamma
Externí odkaz:
https://doaj.org/article/fd261a622e08487782f550c5d0f5bc31
Autor:
Evelien Hesemans, Neshat Saffarzadeh, Christy Maksoudian, Mukaddes Izci, Tianjiao Chu, Carla Rios Luci, Yuqing Wang, Hendrik Naatz, Sebastian Thieme, Cornelia Richter, Bella B. Manshian, Suman Pokhrel, Lutz Mädler, Stefaan J. Soenen
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-28 (2023)
Abstract Nanoparticle-mediated cancer immunotherapy holds great promise, but more efforts are needed to obtain nanoformulations that result in a full scale activation of innate and adaptive immune components that specifically target the tumors. We ge
Externí odkaz:
https://doaj.org/article/4edafa41c145433d9a31b1abb2cc5619
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In December 2019, a novel coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified as the cause of pneumonia with severe respiratory distress and outbreaks in Wuhan, China. The rapid and global spread
Externí odkaz:
https://doaj.org/article/b0aed1a133e74b9f88b53604d16bbdf5
Autor:
Lyn R. Frumkin, Michaela Lucas, Curtis L. Scribner, Nastassja Ortega-Heinly, Jayden Rogers, Gang Yin, Trevor J. Hallam, Alice Yam, Kristin Bedard, Rebecca Begley, Courtney A. Cohen, Catherine V. Badger, Shawn A. Abbasi, John M. Dye, Brian McMillan, Michael Wallach, Traci L. Bricker, Astha Joshi, Adrianus C. M. Boon, Suman Pokhrel, Benjamin R. Kraemer, Lucia Lee, Stephen Kargotich, Mahima Agochiya, Tom St. John, Daria Mochly-Rosen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 emergency use authorizations and approvals for vaccines were achieved in record time. However, there remains a need to develop additional safe, effective, easy-to-produce, and inexpensive prevention to reduce the risk of acquiring SARS-CoV-2
Externí odkaz:
https://doaj.org/article/f9a71f4c09c643bcb9dfa4ae37d246f0
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251426 (2021)
Two SARS-CoV-2 variants of concern showing increased transmissibility relative to the Wuhan virus have recently been identified. Although neither variant appears to cause more severe illness nor increased risk of death, the faster spread of the virus
Externí odkaz:
https://doaj.org/article/c9044de64c9c4b3d92b56c6ee24c1299
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background The biomedical use of nanosized materials is rapidly gaining interest, which drives the quest to elucidate the behavior of nanoparticles (NPs) in a biological environment. Apart from causing direct cell death, NPs can affect cellu
Externí odkaz:
https://doaj.org/article/4c9d61a6af804e2f965d6de9d5b89aa9
Publikováno v:
Materials, Vol 14, Iss 9, p 2395 (2021)
The film thickness plays an important role in the performance of materials applicable to different technologies including chemical sensors, catalysis and/or energy materials. The relationship between the surface and volume of the functional layers is
Externí odkaz:
https://doaj.org/article/f7aeea1014c8429298d642b39ef1fe89
Autor:
Julia Rebholz, Katharina Grossmann, David Pham, Suman Pokhrel, Lutz Mädler, Udo Weimar, Nicolae Barsan
Publikováno v:
Sensors, Vol 16, Iss 9, p 1437 (2016)
Here we present a novel concept for the selective recognition of different target gases with a multilayer semiconducting metal oxide (SMOX)-based sensor device. Direct current (DC) electrical resistance measurements were performed during exposure to
Externí odkaz:
https://doaj.org/article/3f233f8afd9a41be997a694343dca5ab