Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Suman Laal"'
Autor:
Michelle B. Ryndak, Suman Laal
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Globally, tuberculosis (TB) has reemerged as a major cause of morbidity and mortality, despite the use of the Mycobacterium bovis BCG vaccine and intensive attempts to improve upon BCG or develop new vaccines. Two lacunae in our understanding of the
Externí odkaz:
https://doaj.org/article/113525c7fa794475a10a742bffcdd641
Autor:
Sudhanshu Abhishek, Uma Nahar Saikia, Amod Gupta, Reema Bansal, Vishali Gupta, Nirbhai Singh, Suman Laal, Indu Verma
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Background: Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of tuberculosis of the eye, has unique and varied clinical presentations with poorly understood pathogenesis. As it is a significant cause of inflammation and visual morbidi
Externí odkaz:
https://doaj.org/article/e21ba1dcc45a410f90fbd014f4ac8b97
Autor:
Sumedha Sharma, Michelle B Ryndak, Ashutosh N Aggarwal, Rakesh Yadav, Sunil Sethi, Shet Masih, Suman Laal, Indu Verma
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173508 (2017)
Pulmonary tuberculosis, the disease caused by Mycobacterium tuberculosis, still retains a top rank among the deadliest communicable diseases. Sputum expectorated during the disease continues to be a primary diagnostic specimen and also serves as a re
Externí odkaz:
https://doaj.org/article/7ac005f3b5a04a27937ef7db35f4a47b
Publikováno v:
Genomics Data, Vol 5, Iss C, Pp 112-114 (2015)
Alveolar epithelial cells outnumber alveolar macrophages by ~500 fold and increasing evidence suggests that Mycobacterium tuberculosis may replicate dramatically in these cells during the initial weeks of infecting the lung (Wolf et al., 2008 [1]; Ry
Externí odkaz:
https://doaj.org/article/a7b04f6f1e0d4b2e9d62e11c6a341d16
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123745 (2015)
Mycobacterium tuberculosis (M. tb) infection is initiated by the few bacilli inhaled into the alveolus. Studies in lungs of aerosol-infected mice provided evidence for extensive replication of M. tb in non-migrating, non-antigen-presenting cells in t
Externí odkaz:
https://doaj.org/article/bd700bd57997405db34fb345a99f3229
Autor:
Michelle B Ryndak, Krishna K Singh, Zhengyu Peng, Susan Zolla-Pazner, Hualin Li, Lu Meng, Suman Laal
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94939 (2014)
Hematogenous dissemination of Mycobacterium tuberculosis (M. tb) occurs during both primary and reactivated tuberculosis (TB). Although hematogenous dissemination occurs in non-HIV TB patients, in ∼80% of these patients, TB manifests exclusively as
Externí odkaz:
https://doaj.org/article/8d9124ba68d24c369ca7091f0ecaa5a1
Autor:
Jesus M Gonzalez, Bryan Francis, Sherri Burda, Kaitlyn Hess, Digamber Behera, Dheeraj Gupta, Ashutosh Nath Agarwal, Indu Verma, Ajoy Verma, Vithal Prasad Myneedu, Sam Niedbala, Suman Laal
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106279 (2014)
The need for an accurate, rapid, simple and affordable point-of-care (POC) test for Tuberculosis (TB) that can be implemented in microscopy centers and other peripheral health-care settings in the TB-endemic countries remains unmet. This manuscript d
Externí odkaz:
https://doaj.org/article/71868a579ab74b179f9578720dc48dcd
Autor:
Karen R Steingart, Laura L Flores, Nandini Dendukuri, Ian Schiller, Suman Laal, Andrew Ramsay, Philip C Hopewell, Madhukar Pai
Publikováno v:
PLoS Medicine, Vol 8, Iss 8, p e1001062 (2011)
BackgroundSerological (antibody detection) tests for tuberculosis (TB) are widely used in developing countries. As part of a World Health Organization policy process, we performed an updated systematic review to assess the diagnostic accuracy of comm
Externí odkaz:
https://doaj.org/article/5103da4d168345e0b49106a00a269d2a
Autor:
Ajay Wanchu, Yuxin Dong, Sunil Sethi, V P Myneedu, Arthur Nadas, Zhentong Liu, John Belisle, Suman Laal
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2071 (2008)
Simple biomarkers are required to identify TB in both HIV(-)TB(+) and HIV(+)TB(+) patients. Earlier studies have identified the M. tuberculosis Malate Synthase (MS) and MPT51 as immunodominant antigens in TB patients. One goal of these investigations
Externí odkaz:
https://doaj.org/article/4a8704426e6d4ee59df0c26d0d739113
Autor:
Karen R Steingart, Megan Henry, Suman Laal, Philip C Hopewell, Andrew Ramsay, Dick Menzies, Jane Cunningham, Karin Weldingh, Madhukar Pai
Publikováno v:
PLoS Medicine, Vol 4, Iss 8 (2007)
Externí odkaz:
https://doaj.org/article/0c532e7d3ec347149583756b94eccca5