Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Suman Asalla"'
Autor:
Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla, Sumona G. Lester, Getachew D. Belew, Sobia Zaidi, Raziyeh Abdolahipour, Abhishek P. Shrestha, Agnes O. Portuphy, Hannah L. Stankus, Raghd Abu Helal, Stefaan Verhulst, Sergio Duarte, Ali Zarrinpar, Leo A. van Grunsven, Scott L. Friedman, Robert F. Schwabe, Terry D. Hinds, Jr., Sivarajan Kumarasamy, Sonia M. Najjar
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102010- (2024)
Objectives: Hepatic CEACAM1 expression declines with advanced hepatic fibrosis stage in patients with metabolic dysfunction-associated steatohepatitis (MASH). Global and hepatocyte-specific deletions of Ceacam1 impair insulin clearance to cause hepat
Externí odkaz:
https://doaj.org/article/e69d9f2f8521498ea5cb94a3c6b0d26c
Autor:
Ashraf Nahle, Yemisi Deborah Joseph, Sandra Pereira, Yusaku Mori, Frankie Poon, Hilda E. Ghadieh, Aleksandar Ivovic, Tejas Desai, Simona S. Ghanem, Suman Asalla, Harrison T. Muturi, Emelien M. Jentz, Jamie W. Joseph, Sonia M. Najjar, Adria Giacca
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13224 (2021)
The NAD-dependent deacetylase SIRT1 improves β cell function. Accordingly, nicotinamide mononucleotide (NMN), the product of the rate-limiting step in NAD synthesis, prevents β cell dysfunction and glucose intolerance in mice fed a high-fat diet. T
Externí odkaz:
https://doaj.org/article/f88ba7de538c4a80adcd7d91c2eaac40
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Mycobacterium tuberculosis (M.tb) infection manifests into tuberculosis (TB) in a small fraction of the infected population that comprises the TB susceptible group. Identifying the factors potentiating susceptibility to TB persistence is one of the p
Externí odkaz:
https://doaj.org/article/c7b9b3cfa6e449a7abc435dbf3bb55e9
Autor:
Vinay Kumar, Rachel Rosenzweig, Suman Asalla, Sarita Nehra, Sumanth D. Prabhu, Shyam S. Bansal
Publikováno v:
JACC: Basic to Translational Science. 7:1038-1049
Publikováno v:
Physiology. 38
Myocardial infarction (MI) and ischemic heart failure (HF) are associated with immune activation in the bone-marrow and the lymphoid tissues. Our studies also show that spleens lose 58% of their weight by 1-day post-MI as compared to sham-operation.
Publikováno v:
Circulation Research. 131
Ischemic heart failure (HF) is associated with elevated inflammatory responses including pro-inflammatory cytokines, such as Tumor necrosis factor (TNF) α [and its cognate receptors, TNF receptor (TNFR) 1 and TNFR2] and pathological switching of CD4
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 113
Tuberculosis (TB) continues to be the leading cause of death by any single infectious agent, accounting for around 1.7 million annual deaths globally, despite several interventions and support programs by national and international agencies. With the
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Mycobacterium tuberculosis (M.tb) infection manifests into tuberculosis (TB) in a small fraction of the infected population that comprises the TB susceptible group. Identifying the factors potentiating susceptibility to TB persistence is one of the p
Autor:
Subbareddy Maddika, Ramya S. Kuna, Joyprashant Vallentyne, David L. Smiley, Shravan Babu Girada, Suman Asalla, Prasenjit Mitra, James Patterson, Richard D. DiMarchi
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 305:E161-E170
Glucagon-like peptide-1 receptor (GLP-1R) plays a major role in promoting glucose-stimulated insulin secretion in pancreatic β-cells. In the present study, we synthesized a novel functional analog of GLP-1 conjugated to tetramethyl rhodamine to moni
Autor:
Anupama T. Row, Manika Pal Bhadra, Shasi V. Kalivendi, Debabrata Chowdhury, Swetha Pavani Rao, Partha P. Ghosh, Suman Asalla, Bhaskar Kandagatla, Prasenjit Mitra, Ramya S. Kuna, Utpal Bhadra, Ahamed Ibrahim, Srinivas Oruganti, Shravan Babu Girada
Publikováno v:
Scientific Reports
Dyslipidemia, particularly the elevated serum cholesterol levels, aggravate the pathophysiology of type 2 diabetes. In the present study we explored the relationship between fasting blood sugar and serum lipid parameters in human volunteers which rev