Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Sumalee Kamchonwongpaisan"'
Autor:
Nirut Leela, Parichat Prommana, Sumalee Kamchonwongpaisan, Tana Taechalertpaisarn, Philip J. Shaw
Publikováno v:
PeerJ, Vol 12, p e16595 (2024)
Background Plasmodium falciparum possesses a cobalamin-dependent methionine synthase (MS). MS is putatively encoded by the PF3D7_1233700 gene, which is orthologous and syntenic in Plasmodium. However, its vulnerability as an antimalarial target has n
Externí odkaz:
https://doaj.org/article/461d655f64c342c892bb3663b3f503ee
Autor:
Shiroh Iwanaga, Rie Kubota, Tsubasa Nishi, Sumalee Kamchonwongpaisan, Somdet Srichairatanakool, Naoaki Shinzawa, Din Syafruddin, Masao Yuda, Chairat Uthaipibull
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Plasmodium falciparum malaria is treated using artemisinin combination therapy (ACT), in which artemisinin is supplied along with partner drugs such as mefloquine, piperaquine, and lumefantrine. However, resistance has been reported in endemic region
Externí odkaz:
https://doaj.org/article/994ca7c9bea84ed992fa78d880984241
Autor:
Tanyaluck Kampoun, Pimpisid Koonyosying, Jetsada Ruangsuriya, Parichat Prommana, Philip J. Shaw, Sumalee Kamchonwongpaisan, Hery Suwito, Ni Nyoman Tri Puspaningsih, Chairat Uthaipibull, Somdet Srichairatanakool
Publikováno v:
PeerJ, Vol 11, p e15187 (2023)
Background The spread of artemisinin (ART)-resistant Plasmodium falciparum threatens the control of malaria. Mutations in the propeller domains of P. falciparum Kelch13 (k13) are strongly associated with ART resistance. Ferredoxin (Fd), a component o
Externí odkaz:
https://doaj.org/article/9ddd048ae9cc4271866b143b21b28003
Autor:
Christiana J. Dawurung, Minh T. H. Nguyen, Jutharat Pengon, Kanchana Dokladda, Ratchanu Bunyong, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Phuong T. M. Nguyen, Stephen G. Pyne
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Neorautanenia mitis, Hydnora abyssinica, and Senna surattensis are medicinal plants with a variety of traditional uses. In this study, we sought to isolate the bioactive compounds responsible for some of these activities, and to u
Externí odkaz:
https://doaj.org/article/449f83b0a4bd4f32b26a01715895e851
Autor:
Marie Hoarau, Jarunee Vanichtanankul, Nitipol Srimongkolpithak, Danoo Vitsupakorn, Yongyuth Yuthavong, Sumalee Kamchonwongpaisan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 198-206 (2021)
In various malaria-endemic regions, the appearance of resistance has precluded the use of pyrimidine-based antifolate drugs. Here, a three-step fragment screening was used to identify new non-pyrimidine Plasmodium falciparum dihydrofolate reductase (
Externí odkaz:
https://doaj.org/article/a6ce17862162401eab6435a28c72189c
Autor:
Philip J Shaw, Pavita Kaewprommal, Chayaphat Wongsombat, Chumpol Ngampiw, Tana Taechalertpaisarn, Sumalee Kamchonwongpaisan, Sissades Tongsima, Jittima Piriyapongsa
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276956 (2022)
The Plasmodium falciparum human malaria parasite genome is incompletely annotated and does not accurately represent the transcriptomic diversity of this species. To address this need, we performed long-read transcriptomic sequencing. 5' capped mRNA w
Externí odkaz:
https://doaj.org/article/43720a9730ac4faf8e4fbacb580c9ec5
Autor:
Nan Yadanar Lin Pyae, Arnatchai Maiuthed, Wongsakorn Phongsopitanun, Bongkot Ouengwanarat, Warongrit Sukma, Nitipol Srimongkolpithak, Jutharat Pengon, Roonglawan Rattanajak, Sumalee Kamchonwongpaisan, Zin Zin Ei, Preedakorn Chunhacha, Patcharin Wilasluck, Peerapon Deetanya, Kittikhun Wangkanont, Kowit Hengphasatporn, Yasuteru Shigeta, Thanyada Rungrotmongkol, Supakarn Chamni
Publikováno v:
Molecules, Vol 28, Iss 3, p 1104 (2023)
New N-containing xanthone analogs of α-mangostin were synthesized via one-pot Smiles rearrangement. Using cesium carbonate in the presence of 2-chloroacetamide and catalytic potassium iodide, α-mangostin (1) was subsequently transformed in three st
Externí odkaz:
https://doaj.org/article/9bb9e41a21844fdcb618b40f9d8f32f2
Autor:
Philip J. Shaw, Jittima Piriyapongsa, Pavita Kaewprommal, Chayaphat Wongsombat, Chadapohn Chaosrikul, Krirkwit Teeravajanadet, Manon Boonbangyang, Chairat Uthaipibull, Sumalee Kamchonwongpaisan, Sissades Tongsima
Publikováno v:
PeerJ, Vol 9, p e11983 (2021)
Background The genome of the human malaria parasite Plasmodium falciparum is poorly annotated, in particular, the 5′ capped ends of its mRNA transcripts. New approaches are needed to fully catalog P. falciparum transcripts for understanding gene fu
Externí odkaz:
https://doaj.org/article/2b97d41bed9848f1aae2daf5ca316920
Autor:
Marie Hoarau, Nattida Suwanakitti, Thaveechai Varatthan, Ratthiya Thiabma, Roonglawan Rattanajak, Netnapa Charoensetakul, Emily K. Redman, Tanatorn Khotavivattana, Tirayut Vilaivan, Yongyuth Yuthavong, Sumalee Kamchonwongpaisan
Publikováno v:
Molecules, Vol 27, Iss 11, p 3515 (2022)
In the fight towards eradication of malaria, identifying compounds active against new drug targets constitutes a key approach. Plasmodium falciparum 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (PfHPPK) has been advanced as a promising target,
Externí odkaz:
https://doaj.org/article/0a189195d6484648b3cf41230d6d7879
Autor:
Rattanaporn Wansri, Aye Chan Khine Lin, Jutharat Pengon, Sumalee Kamchonwongpaisan, Nitipol Srimongkolpithak, Roonglawan Rattanajak, Patcharin Wilasluck, Peerapon Deetanya, Kittikhun Wangkanont, Kowit Hengphasatporn, Yasuteru Shigeta, Jatupol Liangsakul, Aphinya Suroengrit, Siwaporn Boonyasuppayakorn, Taksina Chuanasa, Wanchai De-eknamkul, Supot Hannongbua, Thanyada Rungrotmongkol, Supakarn Chamni
Publikováno v:
Molecules, Vol 27, Iss 9, p 2841 (2022)
Piper nigrum, or black pepper, produces piperine, an alkaloid that has diverse pharmacological activities. In this study, N-aryl amide piperine analogs were prepared by semi-synthesis involving the saponification of piperine (1) to yield piperic acid
Externí odkaz:
https://doaj.org/article/3c603dafe6ca48c285627729f9f6f080