Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sultan N. Sonbul"'
Autor:
Najat Binothman, Majidah Aljadani, Bandar Alghanem, Mohammed Y. Refai, Mamoon Rashid, Abeer Al Tuwaijri, Nouf H. Alsubhi, Ghadeer I. Alrefaei, Muhammad Yasir Khan, Sultan N. Sonbul, Fadwa Aljoud, Sultan Alhayyani, Rwaa H. Abdulal, Magdah Ganash, Anwar M. Hashem
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Triple-negative breast cancer (TNBC) subtype is characterized by aggressive clinical behavior and poor prognosis patient outcomes. Here, we show that ADAR1 is more abundantly expressed in infiltrating breast cancer (BC) tumors than in benign
Externí odkaz:
https://doaj.org/article/64e95dfbe52d4a438b591a58b7b431ce
Autor:
Chitra Joseph, Andrew R. Green, Sultan N Sonbul, Sami Alsaeed, Mansour Alsaleem, Nigel P. Mongan, Stewart G. Martin, Ian O. Ellis, Takaaki Fujii, Christopher C. Nolan, Sasagu Kurozumi, Yousif A Kariri, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Simon J Johnston, Emad A. Rakha, Marian Pigera, Ken Shirabe
Publikováno v:
Breast Cancer Research and Treatment. 172:61-68
BACKGROUND: Ras association and pleckstrin homology domains 1 (RAPH1) is involved in cytoskeleton regulation and re-epithelialisation in invasive carcinoma and therefore may play a key role in carcinogenesis and metastasis. We herein investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f387af3d0de86cfc8ad6c2fdec7d5d5
https://doi.org/10.1007/s10549-018-4891-y
https://doi.org/10.1007/s10549-018-4891-y
Autor:
Abhik Mukherjee, Ahmed Elmouna, Emad A. Rakha, Sultan N Sonbul, Ibraheem Ashankyty, Carlos Caldas, Ritu Aneja, Ian O. Ellis, Stewart G. Martin, Khalil I Albrahim, Rachel Surridge, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Andrew R. Green
Publikováno v:
British Journal of Cancer
Background:\ud The prognostic value of lymphovascular invasion (LVI) in breast cancer (BC) has been demonstrated in several independent studies. However, identification of driver molecules for LVI remains a challenging task. Large-scale transcriptomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2964973b18a5cb827f7d99c7aa69206b
http://europepmc.org/articles/PMC5674094
http://europepmc.org/articles/PMC5674094
Autor:
Ian O. Ellis, Sultan N Sonbul, Emad A. Rakha, Andrew R. Green, Abhik Mukherjee, Kylie L. Gorringe, Mohammed A. Aleskandarany
Publikováno v:
The Journal of Pathology: Clinical Research. 3:105-114
Some previous studies have reported that the chemokine (C-C motif) receptor 7 (CCR7) plays a role in breast cancer, is associated with lymph node metastasis and drives the site of distant metastasis. However, the impact of its expression on patient o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf0b8ddfdfa7704a2d737ea7931f99b
https://doi.org/10.1002/cjp2.65
https://doi.org/10.1002/cjp2.65
Autor:
Abir A. Muftah, Sultan N Sonbul, Emad A. Rakha, Ian O. Ellis, Andrew R. Green, Carlos Caldas, Christopher C. Nolan, Maria Diez Rodriguez, Mohammed A. Aleskandarany
Publikováno v:
Histopathology. 70:456-465
Background and Aim Although oestrogen receptor (ER)-negative breast cancers (BC) do not respond to hormone therapy, the response of ER-positive BC is reported to be variable which may suggest a dose dependent effect. This study aimed to assess the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e415756bde20487ae39ce8b0922b581
https://doi.org/10.1111/his.13089
https://doi.org/10.1111/his.13089
Autor:
Carlos Caldas, Sultan N Sonbul, Sasagu Kurozumi, Ibraheem Ashankyty, Yousif A Kariri, Leslie W Dalton, Abrar I. Aljohani, Takaaki Fujii, Andrew R. Green, Ian O. Ellis, Sami Alsaeed, Emad A. Rakha, Ken Shirabe, Sara Raafat, Chitra Joseph, Mohammed A. Aleskandarany, Simon J Johnston, Angela Ogden, Mansour Alsaleem, Nigel P. Mongan, Christine Desmedt
Publikováno v:
British Journal of Cancer
BACKGROUND: Lymphovascular invasion (LVI) is associated with the development of metastasis in invasive breast cancer (BC). However, the complex molecular mechanisms of LVI, which overlap with other oncogenic pathways, remain unclear. This study, usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b919514006551e3a3f45dcfdca8d0061
https://pubmed.ncbi.nlm.nih.gov/31114020
https://pubmed.ncbi.nlm.nih.gov/31114020
Autor:
Carlos Caldas, Emad A. Rakha, Andrew R. Green, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Michael S. Toss, Sultan N Sonbul, Abhik Mukherjee, Sasagu Kurozumi, Chitra Joseph, Christopher C. Nolan, Ian O. Ellis, Stewart G. Martin
Lymphovascular invasion is strongly related to breast cancer metastasis. However, the underlying mechanisms of lymphovascular invasion and its driver molecules in breast cancer remain to be defined. In this study, we explore differential expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f74c917629b95b5416c15c7ef56bcba
https://eprints.nottingham.ac.uk/52693/1/SEC14L1_merged.pdf
https://eprints.nottingham.ac.uk/52693/1/SEC14L1_merged.pdf
Autor:
Marian Pigera, Ken Shirabe, Ian O. Ellis, Sultan N Sonbul, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Stewart G. Martin, Emad A. Rakha, Kylie L. Gorringe, Andrew R. Green, Chitra Joseph, Sarah J. Storr, Takaaki Fujii, Hiroyuki Kuwano, Sasagu Kurozumi, Christopher C. Nolan
Publikováno v:
Breast cancer research and treatment. 170(3)
Background: The functions of many proteins are tightly regulated with a complex array of cellular functions including ubiquitination. In cancer cells, aberrant ubiquitination may promote the activity of oncogenic pathways with subsequent tumour progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0426916e23d3fd254b6ba7b28a5a8f
https://pubmed.ncbi.nlm.nih.gov/29633055
https://pubmed.ncbi.nlm.nih.gov/29633055
Autor:
Andrew R. Green, Emad A. Rakha, Carlos Caldas, Christopher C. Nolan, Ian O. Ellis, Sultan N Sonbul, Abir A. Muftah, Maria Diez-Rodriguez, Mohammed A. Aleskandarany, Methaq Mueen Al-Kaabi
Publikováno v:
Breast Cancer Research and Treatment
Background Although the prognostic value of Ki67 in breast cancer is well documented, using optimal cut-points for patient stratification, reproducibility of the scoring and interpretation of the results remains a matter of debate particularly when u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d370a76a7c197304507d4f38dfa038
Autor:
Sultan N, Sonbul, Kylie L, Gorringe, Mohammed A, Aleskandarany, Abhik, Mukherjee, Andrew R, Green, Ian O, Ellis, Emad A, Rakha
Publikováno v:
The Journal of Pathology: Clinical Research
Some previous studies have reported that the chemokine (C‐C motif) receptor 7 (CCR7) plays a role in breast cancer, is associated with lymph node metastasis and drives the site of distant metastasis. However, the impact of its expression on patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a4bdcf3f6b67c5999ee046126e6b051
https://pubmed.ncbi.nlm.nih.gov/28451459
https://pubmed.ncbi.nlm.nih.gov/28451459