Zobrazeno 1 - 10
of 801
pro vyhledávání: '"Sulphonamides"'
Autor:
Mitrowska Kamila, Antczak Maja
Publikováno v:
Journal of Veterinary Research, Vol 68, Iss 2, Pp 249-254 (2024)
No maximum residue limits in honey have been legislated in the EU for antimicrobial substances such as sulphonamides, and they are not permitted, therefore, for treating honey bees unless in a cascade system. Since sulphonamides are used illegally in
Externí odkaz:
https://doaj.org/article/8e2a191565f54eefab31deac303a89df
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 156-165 (2023)
A one-pot two-step protocol was developed for the synthesis of a series of novel 4-cyanamidobenzenesulfonamides from easily accessible methyl (4-sulfamoylphenyl)-carbamimidothioate. The new sulphonamides were investigated as inhibitors of the enzyme
Externí odkaz:
https://doaj.org/article/b78f5378e4f54145a14a8b22ba1dd3de
Publikováno v:
Recent Advances in Natural Sciences, Vol 2, Iss 1 (2024)
The synthesis of functionalized glycine-based sulphonamides via copper catalyzed N-arylation reaction and the in silico, in vitro antibacterial studies is reported. The procedure involved the initial synthesis of substituted p-toluenesulphonamides an
Externí odkaz:
https://doaj.org/article/ce5889a2dcf34b58aa95e3732c6cd02a
Autor:
Heba Abdelrasheed Allam, Mohamed E. Albakry, Walaa R. Mahmoud, Alessandro Bonardi, Shaimaa A. Moussa, Samy Mohamady, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Hany S. Ibrahim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Design and synthesis of three novel series of aryl enaminones (3a–f and 5a–c) and pyrazole (4a-c) linked compounds with sulphonamides, sulfaguanidine, or carboxylic acid functionalities were reported as carbonic anhydrase inhibitors (CAIs) using
Externí odkaz:
https://doaj.org/article/2fc7d8be1b5b42cb8ed9a28b78cc2fa3
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A small library of substituted cyclic guanidine incorporated benzothiazole-6-sulphonamides was synthesized. All obtained compounds were investigated for their inhibitory activity against the key brain-associated human carbonic anhydrase isoform hCA V
Externí odkaz:
https://doaj.org/article/ac94d438f7864dc59e74771f97c2ed5a
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A library of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates was synthesised by selective S-alkylation of the easily accessible 4-thioureidobenzenesulphonamide. The compounds were assayed as inhibitors of four human (h) carbonic anhydrase
Externí odkaz:
https://doaj.org/article/190b79e3ff694b088de0f703e2bc63db
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A small library of novel thiazolone-benzenesulphonamides has been prepared and evaluated for their ability to inhibit three human cytosolic carbonic anhydrases (hCA I, hCA II, and hCA VII) and three bacterial carbonic anhydrases (MscCAβ, StCA1, and
Externí odkaz:
https://doaj.org/article/78761aff2ac64346a46d67d671031268
Autor:
Tarfah Al-Warhi, Mostafa M. Elbadawi, Alessandro Bonardi, Alessio Nocentini, Ahmed A. Al-Karmalawy, Nada Aljaeed, Ohoud J. Alotaibi, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Wagdy M. Eldehna
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2635-2643 (2022)
In this work, different series of benzothiazole-based sulphonamides 8a-c, 10, 12, 16a-b and carboxylic acids 14a-c were developed as novel SLC-0111 analogues with the goal of generating potent carbonic anhydrase (CA) inhibitors. The adopted strategy
Externí odkaz:
https://doaj.org/article/6e3271a462794868b6ff9a0a598fdbf4
Autor:
Mazin A. A. Najm, Walaa R. Mahmoud, Azza T. Taher, Safinaz E-S. Abbas, Fadi M. Awadallah, Heba Abdelrasheed Allam, Daniela Vullo, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2702-2709 (2022)
The present study aimed to develop potent carbonic anhydrase inhibitors (CAIs). The design of the target compounds was based on modifying the structure of the ureido-based carbonic anhydrase inhibitor SLC-0111. Six series of a substituted benzoylthio
Externí odkaz:
https://doaj.org/article/c435c9c5839048bfb876e8744a19fddd
Autor:
Mateusz Kciuk, Adrianna Gielecińska, Somdutt Mujwar, Mariusz Mojzych, Beata Marciniak, Rafał Drozda, Renata Kontek
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1278-1298 (2022)
Carbonic anhydrases IX and CAXII (CAIX/CAXII) are transmembrane zinc metalloproteins that catalyze a very basic but crucial physiological reaction: the conversion of carbon dioxide into bicarbonate with a release of the proton. CA, especially CAIX an
Externí odkaz:
https://doaj.org/article/4aa6f40ea1f64622b22fec14a3440c6a