Zobrazeno 1 - 10
of 1 132
pro vyhledávání: '"Sullenger A"'
Autor:
Lingye Chen, Lyra B. Olson, Ibtehaj A. Naqvi, Bruce A. Sullenger, Loretta G. Que, Thomas N. Denny, Bryan D. Kraft
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Severe COVID-19 carries a high morbidity and mortality. Previous studies have shown an association between COVID-19 severity and SARS-CoV-2 viral load (VL). We sought to measure VL in multiple compartments (urine, plasma, lower re
Externí odkaz:
https://doaj.org/article/8a7d334a2f224a689d615104e20f3409
Autor:
Arianna Carfora, Blake Holthaus, Simon Yacoub, Dominic Franceschelli, Matthew Joseph, Michael W. Milks, Ian Mandybur, Cole Anderson, Catherine Lee, Allyson Huttinger, Mohammad Shujaat, Debra G. Wheeler, Bruce Sullenger, Shahid M. Nimjee
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Background and purposePosterior circulation strokes, accounting for 20% of acute ischemic strokes, significantly contribute to morbidity and mortality. Fibrinolysis by rtPA improves outcomes in stroke but the risk of intracranial hemorrhage limits be
Externí odkaz:
https://doaj.org/article/7c7f7a63760b4945925b8e7b142f6f09
Autor:
Haixiang Yu, Shekhar Kumar, James W. Frederiksen, Vladimir N. Kolyadko, George Pitoc, Juliana Layzer, Amy Yan, Rachel Rempel, Samuel Francis, Sriram Krishnaswamy, Bruce A. Sullenger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Potent and selective inhibition of the structurally homologous proteases of coagulation poses challenges for drug development. Hematophagous organisms frequently accomplish this by fashioning peptide inhibitors combining exosite and active s
Externí odkaz:
https://doaj.org/article/7a6f52c557ba4dfcb62c6ee0bf629bf7
Autor:
Frere, Corinne, Mazzeffi, Michael, Maier, Cheryl L., Helms, Julie, Steiner, Marie E., Sullenger, Bruce A., Tanaka, Kenichi A., Connors, Jean M., Levy, Jerrold H.
Publikováno v:
In Journal of Thrombosis and Haemostasis September 2024 22(9):2608-2628
Autor:
Bryan D. Kraft, Simon Verhulst, Tsung-Po Lai, Bruce A. Sullenger, Yunfei Wang, Wes Rountree, Lingye Chen, Christopher W. Woods, Thomas N. Denny, Abraham Aviv
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Lymphocyte telomere length (TL) is highly variable and shortens with age. Short telomeres may impede TL-dependent T-cell clonal expansion with viral infection. As SARS-CoV-2 infection can induce prolonged and severe T-cell lymphopenia, infected adult
Externí odkaz:
https://doaj.org/article/bd2de7c301b943aabb522de074b07aac
Autor:
Olson, Lyra B., Hunter, Nicole I., Rempel, Rachel E., Yu, Haixiang, Spencer, Diane M., Sullenger, Cynthia Z., Greene, William S., Varanko, Anastasia K., Eghtesadi, Seyed A., Chilkoti, Ashutosh, Pisetsky, David S., Everitt, Jeffrey I., Sullenger, Bruce A.
Publikováno v:
In iScience 22 December 2022 25(12)
Akademický článek
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Autor:
Bethany Powell Gray, Linsley Kelly, Kady-Ann Steen-Burrell, Juliana M. Layzer, Rachel E. Rempel, Shahid M. Nimjee, Brian C. Cooley, Alice F. Tarantal, Bruce A. Sullenger
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 440-451 (2023)
Pathological blood clotting, or thrombosis, limits vital blood flow to organs; such deprivation can lead to catastrophic events including myocardial infarction, pulmonary embolism, and ischemic stroke. Prompt restoration of blood flow greatly improve
Externí odkaz:
https://doaj.org/article/1ee17a94201144fc8700f739b611a006
Autor:
Francesco Puzzo, Chuanling Zhang, Bethany Powell Gray, Feijie Zhang, Bruce A. Sullenger, Mark A. Kay
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 383-397 (2023)
Adeno-associated viruses (AAVs) are commonly used for in vivo gene therapy. Nevertheless, the wide tropism that characterizes these vectors limits specific targeting to a particular cell type or tissue. Here, we developed new chemically modified AAV
Externí odkaz:
https://doaj.org/article/2cb14785ab9043a29a90dad688519651
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102348- (2023)
Summary: Cell isolation from complex mixtures is a key step in many clinical and research applications, but standard isolation methods may affect the cell’s biology and are difficult to reverse. Here, we present a method to isolate and restore cell
Externí odkaz:
https://doaj.org/article/c2eb9f52ea394b57b6bb6eb24749dfe3