Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Sulin Zhang"'
Autor:
Xiaochu Tong, Ning Qu, Xiangtai Kong, Shengkun Ni, Jingyi Zhou, Kun Wang, Lehan Zhang, Yiming Wen, Jiangshan Shi, Sulin Zhang, Xutong Li, Mingyue Zheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Artificial intelligence transforms drug discovery, with phenotype-based approaches emerging as a promising alternative to target-based methods, overcoming limitations like lack of well-defined targets. While chemical-induced transcriptional
Externí odkaz:
https://doaj.org/article/f9cb4b3b840247ea9c97501a4eda7c27
Autor:
Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Gengfu Xiao, Zihe Rao, Lu Lu, Leike Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Respiratory disease caused by coronavirus infection remains a global health crisis. Although several SARS-CoV-2-specific vaccines and direct-acting antivirals are available, their efficacy on emerging coronaviruses in the future, including S
Externí odkaz:
https://doaj.org/article/ed0f8030dd354143aa36edeafd04c36b
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f8b301de2abc4343a3a5c62e7102c682
Autor:
Xingxing Chen, Jun Wang, Xian Zhang, Gui Xiao, Siran Luo, Lei Liu, Weijia Kong, Xiaomin Zhang, Lijing L. Yan, Sulin Zhang
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background With rapid urban sprawl, growing people are living in the vicinity of major roadways. However, little is known about the relationship between residential proximity to major roadways and hearing impairment (HI). Methods We derived
Externí odkaz:
https://doaj.org/article/06ccf3260a9145abb85881b96c50b45d
Autor:
Lifan Chen, Zisheng Fan, Jie Chang, Ruirui Yang, Hui Hou, Hao Guo, Yinghui Zhang, Tianbiao Yang, Chenmao Zhou, Qibang Sui, Zhengyang Chen, Chen Zheng, Xinyue Hao, Keke Zhang, Rongrong Cui, Zehong Zhang, Hudson Ma, Yiluan Ding, Naixia Zhang, Xiaojie Lu, Xiaomin Luo, Hualiang Jiang, Sulin Zhang, Mingyue Zheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Drug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized st
Externí odkaz:
https://doaj.org/article/c4c90579e2754437ac6717ad301ee041
Autor:
Xiaohong Liu, Wei Zhang, Xiaochu Tong, Feisheng Zhong, Zhaojun Li, Zhaoping Xiong, Jiacheng Xiong, Xiaolong Wu, Zunyun Fu, Xiaoqin Tan, Zhiguo Liu, Sulin Zhang, Hualiang Jiang, Xutong Li, Mingyue Zheng
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Artificial intelligence (AI)-based molecular design methods, especially deep generative models for generating novel molecule structures, have gratified our imagination to explore unknown chemical space without relying on brute-force explorat
Externí odkaz:
https://doaj.org/article/58f3ab5eb5cd481997661ea1a3bd6769
Autor:
Zhaoqi Guo, E Tian, Sen Chen, Jun Wang, Jingyu Chen, Weijia Kong, Debbie C. Crans, Yisheng Lu, Sulin Zhang
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 327 (2024)
Noise-induced hearing loss (NIHL) is a prevalent form of adult hearing impairment, characterized by oxidative damage to auditory sensory hair cells. Although certain dihydropyridines, the L-type calcium channel blockers, exhibit protective properties
Externí odkaz:
https://doaj.org/article/4643e4b34e104d6bb7dd147c687a1717
Autor:
Fei Li, Jin Xu, Dan Liu, Jun Wang, Lingmei Lu, Rui Gao, Xiaowen Zhou, Jianhua Zhuang, Sulin Zhang
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveThis study proposes a “modular management” approach for vestibular neuritis (VN) to reduce chronicization and improve patient prognosis. The approach involves multi-factor grading and hierarchical intervention and was found to be more ef
Externí odkaz:
https://doaj.org/article/2e9f8830b52744d0aa4e7d412a89882f
Autor:
Pouria Fattahi, Yin‐Ting Yeh, Tiankai Zhao, Mousa Younesi, Changjin Huang, Mauricio Terrones, Siyang Zheng, Justin L. Brown, Dan Dongeun Huh, Sulin Zhang, Peter J. Butler
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 18, Pp n/a-n/a (2023)
Abstract Endothelial cells (ECs) elongate in the direction of blood flow, are stiffer, and are considered atheroprotective in areas of the vasculature where flow‐induced shear stress is high and unidirectional and are softer, atherogenic, and polyg
Externí odkaz:
https://doaj.org/article/17af808646814899982507d1736fb333
Autor:
Jun Wang, E Tian, Yuejin Zhang, Zhaoqi Guo, Jingyu Chen, Weijia Kong, Yisheng Lu, Sulin Zhang
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1637 (2023)
Background: This study aimed to investigate the effects of unilateral labyrinthectomy (UL) on monoamine neurotransmitters in the medial vestibular nucleus (MVN) of rats. Methods: Adult Sprague–Dawley rats were utilized for the vestibular impaired a
Externí odkaz:
https://doaj.org/article/924f210129ac44b889e0c57b3acba620