Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Suliman Almahmoud"'
Autor:
Sridevi Chigurupati, Fayhaa Saad Alharbi, Suliman Almahmoud, Maha Aldubayan, Yosif Almoshari, Shantini Vijayabalan, Saurabh Bhatia, Sampath Chinnam, Vijayan Venugopal
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 11, Pp 103422- (2021)
Oxidative stress has a crucial role in diabetic pathophysiology, therefore consuming naturally derived antioxidants as a remedial target. This study examines the naturally occurring antioxidant and antidiabetic of Olea europaea L. ethanolic leaves ex
Externí odkaz:
https://doaj.org/article/5fe27f16d84743faa75e526a0d2d1958
Autor:
Suliman Almahmoud, Haizhen A. Zhong
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1614 (2022)
The peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor and controls a number of gene expressions. The ligand binding domain (LBD) of PPARγ is large and involves two binding sites: orthosteric and allosteric binding sites
Externí odkaz:
https://doaj.org/article/66b4a7303ae042199a3854464a49b214
Publikováno v:
Molecules, Vol 24, Iss 11, p 2159 (2019)
Glucose transporter 1 (GLUT1) is a facilitative glucose transporter overexpressed in various types of tumors; thus, it has been considered as an important target for cancer therapy. GLUT1 works through conformational switching from an outward-open (O
Externí odkaz:
https://doaj.org/article/fbd74b6e18ad46829d71374cbccdb525
Autor:
Haizhen A. Zhong, Suliman Almahmoud
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6023
The Janus kinases (JAKs) are a family of non-receptor cytosolic protein kinases critical for immune signaling. Many covalently bound ligands of JAK3 inhibitors have been reported. To help design selective JAK inhibitors, in this paper, we used five m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0463f38621266f58c3a44a257b68ebce
https://doi.org/10.3390/ijms24076023
https://doi.org/10.3390/ijms24076023
Autor:
Haizhen A. Zhong, Catherine C. Elix, Jeremy O. Jones, Suliman Almahmoud, Corey R. Hopkins, Jonathan L. Vennerstrom
Publikováno v:
Bioorganic & Medicinal Chemistry. 46:116368
The peroxisome proliferator-activated receptor gamma (PPARγ) was identified as an oncogene and it plays a key role in prostate cancer (PC) development and progression. PPARγ antagonists have been shown to inhibit PC cell growth. Herein, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618da955f2b35428a69cbe0d02c4fe07
https://doi.org/10.1016/j.bmc.2021.116368
https://doi.org/10.1016/j.bmc.2021.116368
Autor:
Suliman Almahmoud, Jing Wang, Jonathan L. Vennerstrom, Haizhen A. Zhong, Xiaofang Wang, Wei Jin, Liying Geng
Publikováno v:
Bioorganicmedicinal chemistry. 28(7)
Glucose transporters (GLUTs) regulate glucose uptake and are often overexpressed in several human tumors. To identify new chemotypes targeting GLUT1, we built a pharmacophore model and searched against a NCI compound database. Sixteen hit molecules w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d0585e6617a90bde3d6d69852f3662
https://pubmed.ncbi.nlm.nih.gov/32113844
https://pubmed.ncbi.nlm.nih.gov/32113844
Autor:
Haizhen A. Zhong, Suliman Almahmoud
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 18
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4654 (2019)
Volume 20
Issue 18
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4654 (2019)
The programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) is an immune checkpoint (ICP) overexpressed in various types of tumors
thus, it has been considered as an important target for cancer therapy. To determine importa
thus, it has been considered as an important target for cancer therapy. To determine importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb37a53260d2f18b6f266da0bdf3af8b
Publikováno v:
Molecules
Volume 24
Issue 11
Molecules, Vol 24, Iss 11, p 2159 (2019)
Volume 24
Issue 11
Molecules, Vol 24, Iss 11, p 2159 (2019)
Glucose transporter 1 (GLUT1) is a facilitative glucose transporter overexpressed in various types of tumors
thus, it has been considered as an important target for cancer therapy. GLUT1 works through conformational switching from an outward-ope
thus, it has been considered as an important target for cancer therapy. GLUT1 works through conformational switching from an outward-ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8822fbbc53f6f003d48472f8dd0d6ebe
Autor:
Adel Alothman, Suliman Almahmoud, Mohammed Al Ghobain, Suleiman Kojan, Ali M. Al Khathaami, Mohammad Bo Saeed
Publikováno v:
Advances in Infectious Diseases. :63-71
Background: Tuberculosis is an endemic problem that is of important public health concern in Saudi Arabia. Available recent prevalence of tuberculosis (pulmonary and extra-pulmonary) was estimated to be 13.7 per 100,000 people living in the Kingdom o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e3b3a94daeb8ddebd4de2e6f30e3289
https://doi.org/10.4236/aid.2015.51007
https://doi.org/10.4236/aid.2015.51007