Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Suliman Al Humayed"'
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Akademický článek
Crataegus Aronia protects and reverses vascular inflammation in a high fat diet rat model by an antioxidant mechanism and modulating serum levels of oxidized low-density lipoprotein
Autor: Abdullah S. Shatoor, Suliman Al Humayed, Mahmoud A. Alkhateeb, Khalid A. Shatoor, Hussain Aldera, Mohammed Alassiri, Ali A. Shati
Publikováno v: Pharmaceutical Biology, Vol 57, Iss 1, Pp 37-47 (2019)
Context: Crataegus aronia (Willd.) Bosc (Rosaceae) (syn. Azarolus L) is traditionally used to treat cardiovascular disorders. Objectives: To investigate C. aronia protection against a high-fat diet (HFD)-induced vascular inflammation in rats. Materia
Externí odkaz: https://doaj.org/article/93dadb5bf7ea44f1a388f513791159f2
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2
Akademický článek
MiR-155 Dysregulation Is Associated with the Augmentation of ROS/p53 Axis of Fibrosis in Thioacetamide-Induced Hepatotoxicity and Is Protected by Resveratrol
Autor: Amal F. Dawood, Suliman Al Humayed, Maha A. Momenah, Mohamed El-Sherbiny, Hend Ashour, Samaa S. Kamar, Asmaa M. ShamsEldeen, Mohamed A. Haidara, Bahjat Al-Ani, Hasnaa A. Ebrahim
Publikováno v: Diagnostics, Vol 12, Iss 7, p 1762 (2022)
Liver fibrosis is a hallmark of thioacetamide (TAA) intoxications. MicroRNAs (miRs), such as miR-155, have been implied in the pathogenesis of liver disease, and regulated by the antioxidant and anti-inflammatory compound resveratrol (RES). The link
Externí odkaz: https://doaj.org/article/33bd274a9576411487c0ff5eaa253473
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3
Resveratrol suppresses cholestasis‐induced liver injury and fibrosis in rats associated with the inhibition of TGFβ1–Smad3–miR21 axis and profibrogenic and hepatic injury biomarkers
Autor: Ayman M. Farag, Suliman Al Humayed, Mohammed Ali Eshra, Samaa S Kamar, Asmaa Mohammed ShamsEldeen, Mohamed A Haidara, Bahjat Al-Ani, Laila A. Rashed, Hasnaa Ali Ebrahim, Abeer Attia, Amul M. Badr
Publikováno v: Clinical and Experimental Pharmacology and Physiology. 48:1402-1411
Cholestasis caused by slowing or blockage of bile flow is a serious liver disease that can lead to liver fibrosis and cirrhosis. The link between transforming growth factor beta 1 (TGFβ1), Smad family member 3 (Smad3), and microRNA 21 (miR21) in bil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cfdec54190aa97a3dea86776c4d5b3
https://doi.org/10.1111/1440-1681.13546
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4
Short-term administration of C. aronia stimulates insulin signaling, suppresses fatty acids metabolism, and increases glucose uptake and utilization in the hearts of healthy rats
Autor: Abdullah S. Shatoor, Hussain M Almohiy, Suliman Al Humayed
Publikováno v: Saudi Journal of Biological Sciences, Vol 28, Iss 3, Pp 1966-1977 (2021)
Saudi Journal of Biological Sciences
Graphical abstract
This study evaluated the effect of Crataegus aronia (C. aronia) aqueous extract on cardiac substrate utilization and insulin signaling in adult male healthy Wistar rats. Rats (n = 18/group) were either administered normal sali
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5ef68b5443efac65300d1bdca2c745
https://doi.org/10.1016/j.sjbs.2020.12.052
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6
Crataegus aronia prevents high‐fat diet‐induced hepatic steatosis in rats by activating AMPK‐induced suppression of SREBP1 and activation of PPARα
Autor: Hussain M Almohiy, Abdullah S. Shatoor, Suliman Al Humayed
Publikováno v: Journal of Food Biochemistry. 45
This study examined if the aqueous extract of Crataegus aronia (C. aronia) can prevent high-fat diet (HFD)-induced hepatic steatosis in rats by activating AMPK. Adult male Wistar rats were fed either a control diet or HFD for 12 weeks and treated eit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd79f949725d9fc18b4134388a5f3e3
https://doi.org/10.1111/jfbc.13945
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7
Suppression of acetaminophen-induced hepatocyte ultrastructural alterations in rats using a combination of resveratrol and quercetin
Autor: Bahjat Al-Ani, Refaat A. Eid, Abbas O El Karib, Suliman Al Humayed, Shahid Aziz, Abdullah S. Shatoor, Javed Iqbal Wani, Mohamed A Haidara
Publikováno v: Ultrastructural Pathology. 43:162-169
Ingestion of a toxic dose of the analgesic drug, acetaminophen (also called paracetamol or APAP), is among the most common causes of acute liver injury in humans. We tested the hypothesis that the combined polyphenolic compounds, resveratrol (RES) an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e3783e7f01acc5fb3cf1677a37caf4
https://doi.org/10.1080/01913123.2019.1680585
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8
Captopril suppresses hepatic mammalian target of rapamycin cell signaling and biomarkers of inflammation and oxidative stress in thioacetamide-induced hepatotoxicity in rats
Autor: Fahaid Al-Hashem, Bahjat Al-Ani, Noha S Abdel Latif, Suliman Al Humayed, Mohamed A Haidara
Publikováno v: Archives of Physiology and Biochemistry. 127:414-421
The potential inhibitory effects of captopril, the angiotensin-converting enzyme inhibitor, on thioacetamide (TAA)-induced hepatic mammalian target of rapamycin (mTOR), liver injury enzymes, blood pressure, and biomarkers of inflammation and oxidativ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc975d6d025aca16b70e7f5b96106359
https://doi.org/10.1080/13813455.2019.1647249
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9
Crataegus Aronia protects and reverses vascular inflammation in a high fat diet rat model by an antioxidant mechanism and modulating serum levels of oxidized low-density lipoprotein
Autor: Ali A. Shati, Mahmoud A. Alkhateeb, Mohammed Alassiri, Suliman Al Humayed, Khalid A. Shatoor, Abdullah S. Shatoor, Hussain Aldera
Publikováno v: Pharmaceutical Biology
Pharmaceutical Biology, Vol 57, Iss 1, Pp 37-47 (2019)
Context:Crataegus aronia (Willd.) Bosc (Rosaceae) (syn. Azarolus L) is traditionally used to treat cardiovascular disorders. Objectives: To investigate C. aronia protection against a high-fat diet (HFD)-induced vascular inflammation in rats. Material
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dba31439484894e2eae5b3f1ae02733
http://europepmc.org/articles/PMC6366417
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10
Astaxanthin attenuates hepatic steatosis in high-fat diet-fed rats by suppressing microRNA-21 via transactivation of nuclear factor erythroid 2-related factor 2
Autor: Abdullah S, Shatoor, Suliman, Al Humayed, Hussain M, Almohiy
Publikováno v: Journal of physiology and biochemistryReferences. 78(1)
This study examined whether astaxanthin (ASX) could alleviate hepatic steatosis in rats fed a high-fat diet (HFD) by modulating the nuclear factor erythroid 2-related factor 2 (Nrf2)/miR-21 axis. Rats (n = 8/group) were fed either a standard diet (3.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4238ef4c0d6ec59df5915d1c368579ef
https://pubmed.ncbi.nlm.nih.gov/34651285
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