Zobrazeno 1 - 10 of 63 pro vyhledávání: '"Sulggi A Lee"'
1
Akademický článek
A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size.
Autor: Ashok K Dwivedi, Germán G Gornalusse, David A Siegel, Alton Barbehenn, Cassandra Thanh, Rebecca Hoh, Kristen S Hobbs, Tony Pan, Erica A Gibson, Jeffrey Martin, Frederick Hecht, Christopher Pilcher, Jeffrey Milush, Michael P Busch, Mars Stone, Meei-Li Huang, Julieta Reppetti, Phuong M Vo, Claire N Levy, Pavitra Roychoudhury, Keith R Jerome, Florian Hladik, Timothy J Henrich, Steven G Deeks, Sulggi A Lee
Publikováno v: PLoS Pathogens, Vol 19, Iss 11, p e1011114 (2023)
The major barrier to an HIV cure is the HIV reservoir: latently-infected cells that persist despite effective antiretroviral therapy (ART). There have been few cohort-based studies evaluating host genomic or transcriptomic predictors of the HIV reser
Externí odkaz: https://doaj.org/article/7776a4bc1ed44dd486e134024b42b187
Zobrazit plný text záznamu
2
Akademický článek
Assessing the associations between known genetic variants and substance use in people with HIV in the United States.
Autor: Cameron B Haas, Kristina M Jordahl, Robin M Nance, Bridget M Whitney, Lu Wang, Joseph A C Delaney, Stephanie Ruderman, Tongqiu Jia, Wm Christopher Mathews, Michael S Saag, Sulggi A Lee, Sonia Napravnik, Jeffrey M Jacobson, Geetanjali Chander, Elizabeth M McCall, Richard D Moore, Kenneth H Mayer, Shubhabrata Mukherjee, Won Jun Lee, Paul K Crane, Heidi Crane, Inga Peter, Sara Lindström
Publikováno v: PLoS ONE, Vol 18, Iss 10, p e0292068 (2023)
BackgroundThe prevalence of substance use in people with HIV (PWH) in the United States is higher than in the general population and is an important driver of HIV-related outcomes. We sought to assess if previously identified genetic associations tha
Externí odkaz: https://doaj.org/article/a712c4f5e3504e33af83e297d309a195
Zobrazit plný text záznamu
3
Akademický článek
mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status
Autor: Jason Neidleman, Xiaoyu Luo, Matthew McGregor, Guorui Xie, Victoria Murray, Warner C Greene, Sulggi A Lee, Nadia R Roan
Publikováno v: eLife, Vol 10 (2021)
While mRNA vaccines are proving highly efficacious against SARS-CoV-2, it is important to determine how booster doses and prior infection influence the immune defense they elicit, and whether they protect against variants. Focusing on the T cell resp
Externí odkaz: https://doaj.org/article/ba2aa1994fa142fe896a3d30fc57fb45
Zobrazit plný text záznamu
4
Akademický článek
Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.
Autor: Sulggi A Lee, Peter Bacchetti, Nicolas Chomont, Remi Fromentin, Sharon R Lewin, Una O'Doherty, Sarah Palmer, Douglas D Richman, Janet D Siliciano, Steven A Yukl, Steven G Deeks, Peter D Burbelo
Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160192 (2016)
A major challenge to HIV eradication strategies is the lack of an accurate measurement of the total burden of replication-competent HIV (the "reservoir"). We assessed the association of anti-HIV antibody responses and the estimated size of the reserv
Externí odkaz: https://doaj.org/article/498b9450506b48bcbf6e3b27f7a7cb95
Zobrazit plný text záznamu
5
Akademický článek
HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.
Autor: Sergio Serrano-Villar, Talia Sainz, Sulggi A Lee, Peter W Hunt, Elizabeth Sinclair, Barbara L Shacklett, April L Ferre, Timothy L Hayes, Ma Somsouk, Priscilla Y Hsue, Mark L Van Natta, Curtis L Meinert, Michael M Lederman, Hiroyu Hatano, Vivek Jain, Yong Huang, Frederick M Hecht, Jeffrey N Martin, Joseph M McCune, Santiago Moreno, Steven G Deeks
Publikováno v: PLoS Pathogens, Vol 10, Iss 5, p e1004078 (2014)
A low CD4/CD8 ratio in elderly HIV-uninfected adults is associated with increased morbidity and mortality. A subset of HIV-infected adults receiving effective antiretroviral therapy (ART) fails to normalize this ratio, even after they achieve normal
Externí odkaz: https://doaj.org/article/34190c80ee49467aaee778896123b3f0
Zobrazit plný text záznamu
6
Akademický článek
Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.
Autor: Sulggi A Lee, Elizabeth Sinclair, Hiroyu Hatano, Priscilla Y Hsue, Lorrie Epling, Frederick M Hecht, David R Bangsberg, Jeffrey N Martin, Joseph M McCune, Steven G Deeks, Peter W Hunt
Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89444 (2014)
Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase "immunosenesence" of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and increased CD57, a marker of proliferative history. Whether chr
Externí odkaz: https://doaj.org/article/5a31f6e0f95b46b2a9294c998b735773
Zobrazit plný text záznamu
8
Common and Divergent Features of T Cells from Blood, Gut, and Genital Tract of Antiretroviral Therapy–Treated HIV+ Women
Autor: Guorui Xie, Sara Moron-Lopez, David A. Siegel, Kailin Yin, Anastasia Polos, Jennifer Cohen, Ruth M. Greenblatt, Phyllis C. Tien, Sulggi A. Lee, Steven A. Yukl, Nadia R. Roan
Publikováno v: Journal of immunology (Baltimore, Md. : 1950), vol 208, iss 7
T cells residing in mucosal tissues play important roles in homeostasis and defense against microbial pathogens. The gut and female reproductive tract (FRT) are both tolerogenic environments, but they differ in the kinds of foreign Ags they need to t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15fb298a07a1b52b65498af86d8e2f9
https://doi.org/10.4049/jimmunol.2101102
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje