Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Sulfotransferase 1A1"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1764 (2021)
Endogenous factors involved in the progression of cisplatin nephropathy remain undetermined. Here, we demonstrate the toxico-pathological roles of indoxyl sulfate (IS), a sulfate-conjugated uremic toxin, and sulfotransferase 1A1 (SULT1A1), an enzyme
Externí odkaz:
https://doaj.org/article/6ed22b2b5211404abae6dbe2a4d4459d
Autor:
Liming Chen, Junjie Zhu, Lirong Zhang, Xiaochao Ma, Xueyan Shao, Pei Wang, Xiao-bo Zhong, Yifan Bao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 171-185 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obes
Autor:
Saud A. Gohal, Ying Hui, Chunyang Zhou, Eid S. Alatwi, Chunyan Yang, Yongyan Song, Xue Mei, Ming-Cheh Liu
Publikováno v:
Planta medica. 87(6)
Radix Bupleuri is one of the most widely used herbal medicines in China for the treatment of fever, pain, and/or chronic inflammation. Quercitrin, epicatechin, and rutin, the flavonoids present in Radix Bupleuri, have been reported to display anti-in
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1764, p 1764 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1764, p 1764 (2021)
Endogenous factors involved in the progression of cisplatin nephropathy remain undetermined. Here, we demonstrate the toxico-pathological roles of indoxyl sulfate (IS), a sulfate-conjugated uremic toxin, and sulfotransferase 1A1 (SULT1A1), an enzyme
Autor:
S. M. Zahid Hosen, Md. Abul Kalam Azad, Raju Dash, Il Soo Moon, Nayan Dash, Md. Chayan Ali, Md. Abdul Hannan
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 24
Volume 20
Issue 24
Sulfotransferase 1A1 (SULT1A1) is responsible for catalyzing various types of endogenous and exogenous compounds. Accumulating data indicates that the polymorphism rs9282861 (R213H) is responsible for inefficient enzymatic activity and associated wit
Autor:
Noemia Strapazzon, Cynthia M. Gallaher, William Thomas, Jae Kyeom Kim, Sabrina P. Trudo, Dwight R. Stoll, Daniel D. Gallaher
Publikováno v:
Food and Chemical Toxicology. 108:194-202
Cruciferous and apiaceous vegetables may be chemopreventive due to their ability to modulate carcinogen-metabolizing enzymes but whether the effects on such enzymes are sustained over time is unknown. To examine the short- and long-term effects of th
Publikováno v:
Drug Metabolism Reviews. 49:357-371
The interindividual variability in drug response is a major issue in clinical practice and in drug development. Sulfoconjugation is an important Phase II reaction catalyzed by cytosolic sulfotransferases (SULTs), playing a major role in homeostatic f
Autor:
Mo-Li Wu, Xiaochi Ma, Yunpeng Diao, Xiaohong Shu, Xiaodong Ma, Changle Ren, Hong Li, Yang Yang, Sa Deng, Chuangang Li, Yuhong Zhen, Jia Liu
Publikováno v:
Oncotarget
// Yang Yang 1, 2, * , Chuangang Li 3, * , Hong Li 4 , Moli Wu 4 , Changle Ren 5 , Yuhong Zhen 1 , Xiaochi Ma 1 , Yunpeng Diao 1 , Xiaodong Ma 1 , Sa Deng 1 , Jia Liu 4 and Xiaohong Shu 1, 2, * 1 College of Pharmacy, Dalian Medical University, Dalian
Publikováno v:
Proceedings of the National Academy of Sciences. 113:14312-14317
We are just beginning to understand the allosteric regulation of the human cytosolic sulfotransferase (SULTs) family-13 disease-relevant enzymes that regulate the activities of hundreds, if not thousands, of signaling small molecules. SULT1A1, the pr
Publikováno v:
ELECTROPHORESIS.
Sulfotransferases are categorized as phase II metabolic enzymes. Human sulfotransferase 1A1 (SULT1A1) is involved in the sulfonation of xenobiotics with aid from the cofactor 3'-phosphoadenosine-5'-phosphosulfate that acts as a sulfonate donor. In th