Zobrazeno 1 - 10
of 7 146
pro vyhledávání: '"Sulfotransferase"'
Autor:
Nivedita Singh, Anil Kumar Singh
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-25 (2024)
Abstract Cerebroside sulfotransferase (CST) is considered as therapeutic target for substrate reduction therapy (SRT) for metachromatic leukodystrophy (MLD). The present study evaluates the therapeutic potential of 57 phytoconstituents of Withania so
Externí odkaz:
https://doaj.org/article/8781ef6e4241466ab16f7a076d1781ae
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Macular corneal dystrophy (MCD) is an inherited, autosomal recessive disorder of defective keratan sulfate (KS) metabolism. It is caused by the mutations in carbohydrate sulfotransferase 6 gene (CHST6) which is essential for the s
Externí odkaz:
https://doaj.org/article/1eb4634c396b4815b824417b1acabcfb
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background The causal relationships between testosterone, estradiol, estrogen sulfotransferase, and idiopathic pulmonary fibrosis (IPF) are not well understood. This study employs a bidirectional two-sample Mendelian Randomization (MR) appro
Externí odkaz:
https://doaj.org/article/036e9f80a15f486fb1ff7fee011a2fab
Akademický článek
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Autor:
Nivedita Singh, Anil Kumar Singh
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Cerebroside sulfotransferase (CST) is a key enzyme in sulfatide biosynthesis and regulation of the myelin sheath in the nervous system. To counter sulfatide accumulation with the deficiency of aryl sulfatase A, CST is considered a target protein in s
Externí odkaz:
https://doaj.org/article/0972468e65074895ad9a83a1452ec6c4
Autor:
Fatemah A. Alherz
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Human SULT2B1gene is responsible for expressing SULT2B1a and SULT2B1b enzymes, which are phase II metabolizing enzymes known as pregnenolone and cholesterol sulfotransferase (SULT), respectively. They are expressed in several tissues and contribute t
Externí odkaz:
https://doaj.org/article/7295d3491da3465c9ebda46519796041
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Clear cell renal cell carcinoma (ccRCC) is a common malignant tumor, and the role of carbohydrate sulfotransferase 11 (CHST11) in this cancer remains unclear. Here, by using bioinformatics methods, we comprehensively analyzed the relationshi
Externí odkaz:
https://doaj.org/article/95de6c72761c466d96ada2bc240d2641
Autor:
Yuying Zhao, Hanxu Tan, Juping Zhang, Dandan Zhan, Bowen Yang, Shicui Hong, Bo Pan, Neng Wang, Tongkai Chen, Yafei Shi, Zhiyu Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Endocrine therapy is standard for hormone receptor–positive (HR+) breast cancer treatment. However, current strategies targeting estrogen signaling pay little attention to estradiol metabolism in the liver and is usually challenged by trea
Externí odkaz:
https://doaj.org/article/b6dee3d4f2c341358ffc74671102f069
Akademický článek
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Autor:
Robert P. Richter, James D. Odum, Camilla Margaroli, Jessica C. Cardenas, Lei Zheng, Kaushlendra Tripathi, Zhangjie Wang, Katelyn Arnold, Ralph D. Sanderson, Jian Liu, Jillian R. Richter
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Heparan sulfate (HS) in the vascular endothelial glycocalyx (eGC) is a critical regulator of blood vessel homeostasis. Trauma results in HS shedding from the eGC, but the impact of trauma on HS structural modifications that could influe
Externí odkaz:
https://doaj.org/article/9239c9e753ab4de0b3413a2947abf746