Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Sulfonylurea receptor 1"'
Autor:
Jessica Cummings, Yijen L. Wu, C. Edward Dixon, Jeremy Henchir, J. Marc Simard, Ashok Panigrahy, Patrick M. Kochanek, Ruchira M. Jha, Rajesh K. Aneja
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Sepsis-associated brain injury (SABI) is characterized by an acute deterioration of mental status resulting in cognitive impairment and acquisition of new and persistent functional limitations in sepsis survivors. Previously, we reported tha
Externí odkaz:
https://doaj.org/article/09fef268cec240d990a9cc47f2ca7af1
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 3, Pp 488-496 (2022)
Sulfonylurea receptor (SUR) belongs to the adenosine 5′-triphosphate (ATP)-binding cassette (ABC) transporter family; however, SUR is associated with ion channels and acts as a regulatory subunit determining the opening or closing of the pore. Abcc
Externí odkaz:
https://doaj.org/article/1bad689e39254643a90942c1a29081e6
Autor:
Shinsuke Uraki, Hiroto Furuta, Masakazu Miyawaki, Norihiko Matsutani, Yuko Shima, Miki Iwamoto, Shohei Matsuno, Shuhei Morita, Machi Furuta, Asako Doi, Hiroshi Iwakura, Hiroyuki Ariyasu, Masahiro Nishi, Hiroyuki Suzuki, Takashi Akamizu
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 2, Pp 502-505 (2020)
Abstract Neonatal diabetes is a rare disease, often caused by a monogenic abnormality. A male infant patient developed diabetic ketoacidosis at 2 months‐of‐age due to the heterozygous ABCC8 gene mutation (p.Pro1198Leu). After genetic diagnosis, i
Externí odkaz:
https://doaj.org/article/3732ee6cb89945f1b9ead2c464ff50d2
Akademický článek
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Autor:
Xiaojun Zhou, Chunmei Xu, Zhiwei Zou, Xue Shen, Tianyue Xie, Rui Zhang, Lin Liao, Jianjun Dong
Publikováno v:
Molecular Medicine, Vol 25, Iss 1, Pp 1-12 (2019)
Abstract Background Sulfonylurea receptor 1 (SUR1) is primarily responsible for glucose regulation in normal conditions. Here, we sought to investigate the glucose metabolism characteristics of SUR1 −/− rats. Methods The TALEN technique was used
Externí odkaz:
https://doaj.org/article/d9953217e28048b7ba32dfc22c591d9f
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 12, Pp 2539-2552 (2018)
Zachary A King,1 Kevin N Sheth,1 W Taylor Kimberly,2 J Marc Simard3 1Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale University School of Medicine, New Haven, CT, USA; 2Department of Neurology, Division of Neuroc
Externí odkaz:
https://doaj.org/article/ce4da2e1eebd458b8b3b00ddcfa2ca30
Akademický článek
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Publikováno v:
eLife, Vol 6 (2017)
Sulfonylureas are anti-diabetic medications that act by inhibiting pancreatic KATP channels composed of SUR1 and Kir6.2. The mechanism by which these drugs interact with and inhibit the channel has been extensively investigated, yet it remains unclea
Externí odkaz:
https://doaj.org/article/45ffb1774f404afaa6059c2f3b6c01ff
Autor:
J. Marc Simard, Volodymyr Gerzanich, Turhan Coksaygan, Svetlana Ivanova, Gary Schwartzbauer, Melda Gurakar, Hina Ijaz, Cigdem Tosun, Michael T. Koltz, David B. Kurland
Publikováno v:
Brain Sciences, Vol 3, Iss 1, Pp 215-238 (2013)
We studied a model of hemorrhagic encephalopathy of prematurity (EP) that closely recapitulates findings in humans with hemorrhagic EP. This model involves tandem insults of 20 min intrauterine ischemia (IUI) plus an episode of elevated venous pressu
Externí odkaz:
https://doaj.org/article/daf39d29b2104a56ad627ccc8fb722f8
Akademický článek
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