Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Suleyman Akocak"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
A novel series of twelve aromatic bis-ureido-substituted benzenesulfonamides was synthesised by conjugation of aromatic aminobenzenesulfonamides with aromatic bis-isocyanates. The obtained bis-ureido-substituted derivatives were tested against four s
Externí odkaz:
https://doaj.org/article/27d3d6164b084861b578bf702b6f3f3b
Autor:
Nabih Lolak, Mehmet Boga, Muhammed Tuneg, Gulcin Karakoc, Suleyman Akocak, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 424-431 (2020)
A series of 16 novel benzenesulfonamides incorporating 1,3,5-triazine moieties substituted with aromatic amines, dimethylamine, morpholine and piperidine were investigated. These compounds were assayed for antioxidant properties by using 1,1-diphenyl
Externí odkaz:
https://doaj.org/article/e79e1240f39d4a6a98545ce1f7db7dab
Autor:
Mehmet Oguz, Erbay Kalay, Suleyman Akocak, Alessio Nocentini, Nebih Lolak, Mehmet Boga, Mustafa Yilmaz, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1215-1223 (2020)
A series of novel calix[4]azacrown substituted sulphonamide Schiff bases was synthesised by the reaction of calix[4]azacrown aldehydes with different substituted primary and secondary sulphonamides. The obtained novel compounds were investigated as i
Externí odkaz:
https://doaj.org/article/0f89ebb89dde45aea88d26dfdb740011
Autor:
Mustafa Durgun, Cüneyt Türkeş, Mesut Işık, Yeliz Demir, Ali Saklı, Ali Kuru, Abdussamat Güzel, Şükrü Beydemir, Suleyman Akocak, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 950-962 (2020)
Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were synthesised and characterised by FT-IR, 13C NMR, 1H NMR, LC-MS and elemental analysis. Their inhibito
Externí odkaz:
https://doaj.org/article/eee04bfa1cfc44a4853cd06f8fde7298
Autor:
Dilek Canakci, Ismail Koyuncu, Nabih Lolak, Mustafa Durgun, Suleyman Akocak, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 110-116 (2019)
In this study, a series of 10 novel copper (II) and silver complexes of 1,3-diaryltriazene-substituted sulfonamides was synthesised. All the synthesised ligands and their metal complexes were assessed for in vitro cytotoxicity against human colorecta
Externí odkaz:
https://doaj.org/article/e0b61a950fcc4080bc3d14b488817fb1
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1193-1198 (2019)
A series of histamine bis-Schiff bases and bis-spinaceamine derivatives were synthesised and investigated as activators of four human (h) carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the cytosolic hCA I, II and VII, and the membrane-associated hCA I
Externí odkaz:
https://doaj.org/article/c13a038da8794a79ac78bd0ea03efaf2
Autor:
Suleyman Akocak, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1652-1659 (2019)
Eight genetically distinct carbonic anhydrase (EC 4.2.1.1) enzyme families (α-, β-, γ- δ-, ζ-, η-, θ- and ι-CAs) were described to date. On the other hand, 16 mammalian α-CA isoforms are known to be involved in many diseases such as glaucoma
Externí odkaz:
https://doaj.org/article/de9bea0689034331a76a1e7fb2bc95d1
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1575-1580 (2018)
A series of new 1,3-diaryltriazene sulfonamides was synthesised by reaction of diazonium salt of metanilamide (3-aminobenzene sulfonamide) with substituted aromatic amines. The obtained new compounds were assayed as inhibitors of four physiologically
Externí odkaz:
https://doaj.org/article/6c477f8f06354da8acb1300a11cde22b
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1305-1312 (2017)
A series of 20 histamine Schiff base was synthesised by reaction of histamine, a well known carbonic anhydrase (CA, E.C 4.2.2.1.) activator pharmacophore, with substituted aldehydes. The obtained histamine Schiff bases were assayed as activators of f
Externí odkaz:
https://doaj.org/article/387bbb09fb064bddaf03e10a9e1bedc7
Autor:
Suleyman Akocak, Nebih Lolak, Hatice Esra Duran, Mesut Işık, Cüneyt Türkeş, Mustafa Durgun, Şükrü Beydemir
Sulfonamide compounds known as human carbonic anhydrase (hCA) inhibitors are used in the treatment of many diseases such as epilepsy, antibacterial glaucoma, various diseases. 1,3-diaryl-substituted triazenes and sulfaguanidine are used for therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eebe77f75bad7fe5d08c1b026d857a0
https://doi.org/10.21203/rs.3.rs-2812331/v1
https://doi.org/10.21203/rs.3.rs-2812331/v1
