Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Suleman S. Hussain"'
Publikováno v:
Viruses, Vol 13, Iss 10, p 1998 (2021)
Papillomaviruses dysregulate the G1/S cell cycle transition in order to promote DNA synthesis in S phase, which is a requirement for viral replication. The human papillomaviruses (HPV) E6 and E7 oncoproteins mediate degradation of the cell cycle regu
Externí odkaz:
https://doaj.org/article/f4c8e83b409649eca8da18674edc533b
Publikováno v:
Viruses, Vol 13, Iss 1998, p 1998 (2021)
Viruses
Viruses
Papillomaviruses dysregulate the G1/S cell cycle transition in order to promote DNA synthesis in S phase, which is a requirement for viral replication. The human papillomaviruses (HPV) E6 and E7 oncoproteins mediate degradation of the cell cycle regu
Abstract 4: Intercepting ribosomal protein S6KB1 signaling: Prevention of prostate cancer recurrence
Autor:
Addanki Pratap Kumar, Alison Clark, Michelle Villarreal, Sridharan Jayamohan, Shih-Bo Huang, Suleman S. Hussain, Xiaoyu Yang, Paul Rivas, Darpan Patel, Bethany L. Pierce, Shreya Tripathy, Pawel Osmulski, Maria Gaczynska, Lai Zhao, Li-Ju Wang, Yidong Chen, Caroline Xavier Paul Ezhilan, Mohan Natarajan, Joel E. Michalek, Robert L. Reddick, Rita Ghosh
Publikováno v:
Cancer Research. 82:4-4
There is an urgent need for innovative strategies such as the discovery of adjuvants that can prevent relapse and improve quality of life for patients treated with radiotherapy. Previously we demonstrated the utility of Nexrutine (Nex) as a neo-adjuv
Autor:
Jonathan E. Leeman, Manisha Jalan, Rama Rao Damerla, Edin Hamzic, Suleman S. Hussain, Daniel S. Higginson, Kyrie S. Anderson, Christopher Sifuentes, Pavithran T. Ravindran, Yi Li, Grace M. Moore, Neeman Mohibullah, Maximilian J Bazil, Rekha Soni, Rahul Majumdar, Simon N. Powell, Himanshi Narang, Erika S Buechelmaier, Andrea Farina, Agnes Viale, Xiaoqing Rong-Mullins
Publikováno v:
Nucleic Acids Research
Double strand break (DSB) repair primarily occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homologous recombination (HR). Typical methods to measure pathway usage include integrated cassette reporte
Autor:
Roble Bedolla, Li-Ju Wang, Zhao Lai, Yu-Chiao Chiu, Pawel A. Osmulski, Yi Chen, Xiaoyu Yang, Addanki P. Kumar, Shih-Bo Huang, Maria Gaczynska, Dinesh Thapa, Paul Rivas, Rita Ghosh, Robert Reddick, C. Shudde, Suleman S. Hussain, Hiroshi Miyamoto, Amanda R. Muñoz
Publikováno v:
Cancer letters. 505
The NAD+-dependent deacetylase, Sirtuin 1 (SIRT1) is involved in prostate cancer pathogenesis. However, the actual contribution is unclear as some reports propose a protective role while others suggest it is harmful. We provide evidence for a context
Autor:
Christopher Sifuentes, Andrea Farina, Grace M. Moore, Erika S. Buechelmaier, Jonathan E. Leeman, Rama Rao Damerla, Neeman Mohibullah, Kyrie S. Anderson, Rahul Majumdar, Daniel S. Higginson, Himanshi Narang, Agnes Viale, Pavithran T. Ravindran, Simon N. Powell, Rekha Soni, Manisha Jalan, Suleman S. Hussain, Yi Li, Edin Hamzic, Xiaoqing Rong-Mullins
Publikováno v:
SSRN Electronic Journal.
Double strand break (DSB) repair mainly occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homologous recombination (HR). We present an assay system that enables simultaneous measurement of all three p
Autor:
Roble Bedolla, Shih-Bo Huang, Hiroshi Miyamoto, Tim H M Huang, Brad H. Pollock, I-Tien Yeh, Paul Rivas, Suleman S. Hussain, Addanki P. Kumar, Gregory P. Swanson, Nikos Papanikolaou, Ganesh Narayanasamy, Rita Ghosh, Robert Reddick, Joseph W. Basler
Publikováno v:
Cancer Letters. 433:232-241
Radiation therapy (XRT) is a standard treatment for prostate cancer (PCa). Although dose escalation increases local control, toxicity hampers further escalation. Broader improvement will be possible by the addition of adjuvant therapies, which can sy
Autor:
Andrew C. Bell, Nadeem Riaz, Pedro Blecua, Rahul Majumdar, Himanshi Narang, Rama Rao Damerla, Suleman S. Hussain, Pavithran T. Ravindran, Daniel S. Higginson, Xiaoqing Rong-Mullins, Nancy Y. Lee, Simon N. Powell, Yi Li, Jonathan E. Leeman
Squamous cell carcinomas (SCCs) arising from aerodigestive or anogenital epithelium that are associated with the human papillomavirus (HPV) are far more readily cured with radiation therapy than HPV-negative SCCs. The mechanism behind this increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369eb1da4cd5880bdfc499d7e9412463
https://europepmc.org/articles/PMC6815166/
https://europepmc.org/articles/PMC6815166/
Autor:
Shih-Bo Huang, Addanki P. Kumar, Li-Ju Wang, Sridharan Jayamohan, Yi Chen, Alison Clark, Hiroshi Miyamoto, Xiaoyu Yang, Caroline R. D. Xavier Paul Ezhilan, Mohan Natarajan, Michelle R. Villarreal, Roble Bedolla, Rita Ghosh, Paul Rivas, Joel E. Michalek, Robert Reddick, Suleman S. Hussain
Publikováno v:
Clinical Cancer Research. 27:PO-085
Radiation therapy (RT) is a standard treatment for organ confined prostate cancer (PCa). Given that both intrinsic and acquired resistance to radiation causes progression to advanced metastatic PCa, there is an unmet need for adjuvant therapies that
Publikováno v:
Seminars in Cancer Biology. :233-246
The rise in cancer incidence and mortality in developing countries together with the human and financial cost of current cancer therapy mandates a closer look at alternative ways to overcome this burgeoning global healthcare problem. Epidemiological