Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Suleiman W Bahouth"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63379 (2013)
Previous studies have determined that the type-1 PDZ sequence at the extreme carboxy-terminus of the ß1-adrenergic receptor (ß1-AR) binds SAP97 and AKAP79 to organize a scaffold involved in trafficking of the ß1-AR. In this study we focused on cha
Externí odkaz:
https://doaj.org/article/9bb5220e3f234ac1af80491637a33972
Publikováno v:
Biochemical pharmacology. 208
SAP97 is a member of the MAGUK family of proteins, but unlike other MAGUK proteins that are selectively expressed in the CNS, SAP97 is also expressed in peripheral organs, like the heart and kidneys. SAP97 has several protein binding cassettes, and t
Publikováno v:
American Journal of Physiology-Renal Physiology. 317:F375-F387
Arginine-vasopressin (AVP)-mediated translocation of aquaporin-2 (AQP2) protein-forming water channels from storage vesicles to the membrane of renal collecting ducts is critical for the renal conservation of water. The type-1 PDZ-binding motif (PBM)
Autor:
Suleiman W. Bahouth, Mahammed Nooh
Publikováno v:
The FASEB Journal. 35
Publikováno v:
Molecular Pharmacology. 94:862-875
The β1-adrenergic receptor (β1-AR) is a major cardiac G protein-coupled receptor, which mediates cardiac actions of catecholamines and is involved in genesis and treatment of numerous cardiovascular disorders. In mammalian cells, catecholamines ind
Autor:
Mohammed M. Nooh, Suleiman W. Bahouth
Publikováno v:
Cellular Signalling. 29:192-208
Recycling of the majority of agonist-internalized GPCR is dependent on a type I-PDZ "barcode" in their C-tail. The recycling of wild-type (WT) s1-AR is also dependent on its default "type-1 PDZ barcode", but trafficking of the s1-AR is inhibited when
Publikováno v:
Am J Physiol Renal Physiol
Arginine-vasopressin (AVP)-mediated translocation of aquaporin-2 (AQP2) protein-forming water channels from storage vesicles to the membrane of renal collecting ducts is critical for the renal conservation of water. The type-1 PDZ-binding motif (PBM)
Publikováno v:
Biochemical Pharmacology. 120:22-32
β1-Adrenergic receptor (β1-AR) agonists and antagonists are widely used in the treatment of major cardiovascular diseases such as heart failure and hypertension. The β1-AR like other G protein-coupled receptors (GPCRs) are endocytosed in response
Autor:
Suleiman W. Bahouth, Mohammed M. Nooh
Publikováno v:
The FASEB Journal. 34:1-1
Novel paradigms governing β 1 ‐adrenergic receptor trafficking in primary adult rat cardiac myocytes
Publikováno v:
The FASEB Journal. 32