Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sulaiman H Hassan"'
Autor:
Xiaoming Hu, Sulaiman H Hassan, Sicheng Li, Rehana K. Leak, Jingyan Zhao, Lawrence R. Wechsler, Qing Ye, Yejie Shi, Yaan Liu, Jun Chen, Rongrong Wang, Marcelo Rocha
Publikováno v:
J Cereb Blood Flow Metab
Blood monocytes/macrophages infiltrate the brain after ischemic stroke and critically influence brain injury and regeneration. We investigated stroke-induced transcriptomic changes of monocytes/macrophages by RNA sequencing profiling, using a mouse m
Autor:
Ling, Zhu, Sulaiman H, Hassan, Xuguang, Gao, Joycelyn Q, Johnson, Yangfan, Wang, M Victoria, Bregy, Zhishuo, Wei, Jun, Chen, Peiying, Li, R Anne, Stetler
Publikováno v:
Aging and disease. 13:1862
Adaptable and consistent neural function relies at least in part on the ongoing repair of oxidative damage that can accumulate in the brain over a lifespan. To determine whether forebrain neuron-targeted knockout of AP endonuclease 1 (APE1), a critic
Autor:
Xiaoming Hu, Wenting Zhang, Marcelo Rocha, Ligen Shi, Jun Chen, Sulaiman H Hassan, Jianhua Luo, Yejie Shi, Ming Jiang, Lawrence R. Wechsler, Maya N Adair, Liqiang Liu, Jing Xu, Qing Ye, Sicheng Li
Publikováno v:
J Cereb Blood Flow Metab
Senescence-associated alterations in microglia may have profound impact on cerebral homeostasis and stroke outcomes. However, the lack of a transcriptome-wide comparison between young and aged microglia in the context of ischemia limits our understan
Autor:
R. Anne Stetler, Hongjian Pu, Sulaiman H Hassan, Kai Zhang, Xuejing Zhang, Ping Sun, Xuelian Tang, Ke-Jie Yin, Jun Chen
Publikováno v:
Circ Res
Rationale: Angiogenesis promotes neurological recovery after stroke and is associated with longer survival of stroke patients. Cerebral angiogenesis is tightly controlled by certain microRNAs (miRs), such as the miR-15a/16-1 cluster, among others. Ho
Autor:
Michael Bennett, M. Victoria Bregy, Jingyan Zhao, Yejie Shi, Mingyue Xu, Sulaiman H Hassan, R. Anne Stetler, Jun Chen
Publikováno v:
Stroke. 51
Oxidative DNA damage (ODD) after cerebral ischemia/reperfusion injury occurs rapidly and has been implicated in the patholgenesis of ischemic injury. Ischemic ODD in the brain are primarly characterized as apurinic/apyrimidinic (AP) sites and single
Autor:
Yejie Shi, Jun Chen, Sulaiman H Hassan, Rehana K. Leak, Lawrence R. Wechsler, Marcelo Rocha, Rongrong Wang, Xiaoming Hu, Jingyan Zhao, Qing Ye, Yaan Liu
Publikováno v:
Stroke. 51
Introduction: Blood monocytes/macrophages (MΦ) infiltrate the brain in massive numbers after ischemic stroke, but their functional roles in the post-stroke brain remain elusive. Methods: We sorted CD11b + CD45 high monocytes/MΦ from mouse blood and
Autor:
Sulaiman H Hassan, Yejie Shi, Xiaoming Hu, Hongjian Pu, Yanqin Gao, Mingyue Xu, Jun Chen, R. Anne Stetler, Rehana K. Leak, Jun Suenaga
Publikováno v:
Experimental Neurology. 272:109-119
Most of the successes in experimental models of stroke have not translated well to the clinic. One potential reason for this failure is that stroke mainly afflicts the elderly and the majority of experimental stroke studies rely on data gathered from
Autor:
Sulaiman H Hassan, Xuelian Tang, Kai Zhang, R. A. Stetler, Ping Sun, Jun Chen, Ke-Jie Yin, Kai Liu, Hongjian Pu
Publikováno v:
Stroke. 49
Introduction: Angiogenesis promotes functional recovery and is associated with longer survival time in stroke patients. Accumulating studies have shown important roles for microRNAs (miRs) in regulating angiogenesis. Previously, we have demonstrated
Autor:
Ping Sun, Ke-Jie Yin, Yejie Shi, Sulaiman H Hassan, Kai Liu, R. Anne Stetler, Xinxin Yang, Jun Chen, Xuelian Tang
Background and Purpose— Dysregulation of the miR-15a/16-1 cluster in plasma has been reported in patients with stroke as a potential biomarker for diagnostic and prognostic use. However, the essential role and therapeutic potential of the miR-15a/1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e03eb467ef13fc3bb96d09f7f2e0340
https://europepmc.org/articles/PMC5516963/
https://europepmc.org/articles/PMC5516963/
Autor:
Yejie Shi, Jun Chen, Sulaiman H Hassan, Dandan Hong, Wenting Zhang, Hongjian Pu, Zhishuo Wei, Jialin Liu, Xiaoyan Jiang, Ling Chen, Hengxing Meng
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Traumatic brain injury (TBI) is one of the most disabling clinical conditions that could lead to neurocognitive disorders in survivors. Our group and others previously reported that prophylactic enrichment of dietary omega-3 polyunsaturated fatty aci