Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sul'man TB"'
Autor:
N. A. Vikulova, A. D. Dokuchaev, L. V. Nikitina, Sul'man Tb, E. V. Shikhaleva, Leonid B. Katsnelson
Publikováno v:
Biophysics. 61:765-775
Mechano-calcium feedbacks that provide fine tuning of electrical and calcium activation of the heart muscle to mechanical conditions of contractions are an important element of electromechanical coupling as a key mechanism of the autoregulation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c6f1afd47278857d472ea624b00c41
https://doi.org/10.1134/s0006350916050043
https://doi.org/10.1134/s0006350916050043
Publikováno v:
2018 Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT).
Our new mathematical model of the electromechanical coupling in human ventricular cardiomyocytes combines human-specific O'Hara-Rudy electrophysiological model and a sub-model of myocardium mechanics and its calcium activation adopted from our develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f252b6609986fafc9d7392bcde37dd55
https://doi.org/10.1109/usbereit.2018.8384541
https://doi.org/10.1109/usbereit.2018.8384541
Publikováno v:
Biophysics. 54:39-46
A mathematical model was used for comparative analysis of the contribution to the myocardial mechanical activity of two potentially possible variants of the cooperative influence of myosin cross-bridges on calcium activation of sarcomere actin filame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7df1be6d8bfd725752dbf33b5d8c63e
https://doi.org/10.1134/s0006350909010072
https://doi.org/10.1134/s0006350909010072
Publikováno v:
Bulletin of Mathematical Biology. 70:910-949
A mathematical model of the cardiomyocyte electromechanical function is used to study contribution of mechanical factors to rhythm disturbances in the case of the cardiomyocyte calcium overload. Particular attention is paid to the overload caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d62428fcfd209a910058a221ee97c0
https://doi.org/10.1007/s11538-007-9285-y
https://doi.org/10.1007/s11538-007-9285-y
Publikováno v:
CinC
There is a complicated interplay between different factors contributing to the calcium regulation of the heart muscle contraction. Mathematical modeling is an efficient approach to analyze this compound system and recognize the key links. In this wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf79b264cb54eb95055a3f2b47a5af9
https://doi.org/10.1109/cic.2015.7408651
https://doi.org/10.1109/cic.2015.7408651
Publikováno v:
Biophysics. 51:917-926
Mathematical models of the electromechanical function of cardiomyocytes and muscle duplexes, the simplest mechanically inhomogeneous myocardial systems, are developed. Using these models, the contribution of mechanoelectrical feedbacks to the contrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a6fceb8627664efa74334a3adfcaf1
https://doi.org/10.1134/s000635090606011x
https://doi.org/10.1134/s000635090606011x
Autor:
Olga Solovyova, Yuri Protsenko, Leonid B. Katsnelson, P. V. Konovalov, A. A. Balakin, Vladimir S. Markhasin, Sul'man Tb, Oleg Lookin
Publikováno v:
Progress in biophysics and molecular biology. 107(1)
It is well-known that Ca 2þ overload in cardiomyocytes may underlie arrhythmias. However, the possible contribution of mechanical factors to rhythm disturbances in Ca 2þ overloaded myocytes has not been sufficiently investigated. We used a mathemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e983949c1009e5ec0e1342a76da31b0f
https://pubmed.ncbi.nlm.nih.gov/21699912
https://pubmed.ncbi.nlm.nih.gov/21699912
Publikováno v:
Journal of theoretical biology. 272(1)
Cardiomyocyte Ca(2+) overload is closely linked to cardiac arrhythmias. We have earlier shown in a mathematical model that myocardium mechanical activity may contribute to rhythm disturbances induced by Ca(2+) overload in cardiomyocytes with reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ab4c7d6c49737ae4fd7fa5404ee448
https://pubmed.ncbi.nlm.nih.gov/21130101
https://pubmed.ncbi.nlm.nih.gov/21130101
Publikováno v:
Functional Imaging and Modeling of the Heart ISBN: 9783540729068
FIMH
FIMH
Rhythm disturbances and mechanical function suppression proper to the acute heart failure in the case of cardiomyocyte calcium overload are simulated in a mathematical model of cardiomyocyte electromechanical activity. Particular attention is paid to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf85fa39a55906239543f5184e38430
https://doi.org/10.1007/978-3-540-72907-5_39
https://doi.org/10.1007/978-3-540-72907-5_39
Publikováno v:
Biofizika [Biofizika] 2009 Jan-Feb; Vol. 54 (1), pp. 53-61.