Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Sukwoo Choi"'
Autor:
Junghwa Lee, Sukwoo Choi
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103434- (2024)
Summary: The study of defensive behaviors in predicting action outcomes in novel situations without trial and error is limited by the lack of appropriate animal models. Here, we present a protocol for preparing and using a delayed safety-seeking task
Externí odkaz:
https://doaj.org/article/1d3237dbc35b4fb8aea615a95321850c
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113748- (2024)
Summary: Animals are known to exhibit innate and learned forms of defensive behaviors, but it is unclear whether animals can escape through methods other than these forms. In this study, we develop the delayed escape task, in which male rats temporar
Externí odkaz:
https://doaj.org/article/13a3faca61884eb4a4f72e0bd40ccd95
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The balance between activities of fear neurons and extinction neurons in the basolateral nucleus of the basal amygdala (BAL) has been hypothesized to encode fear states after extinction. However, it remains unclear whether these neurons are
Externí odkaz:
https://doaj.org/article/3a362914a1ae46b190d038706dfddc35
Publikováno v:
eLife, Vol 6 (2017)
There has been a longstanding debate on whether original fear memory is inhibited or erased after extinction. One possibility that reconciles this uncertainty is that the inhibition and erasure mechanisms are engaged in different phases (early or lat
Externí odkaz:
https://doaj.org/article/b1c91969b52049cda1111fde6643ed6c
Autor:
Kyungjoon Park, Beomjong Song, Jeongyeon Kim, Ingie Hong, Sangho Song, Junuk Lee, Sungmo Park, Jihye Kim, Bobae An, Hyun Woo Lee, Seungbok Lee, Hyun Kim, Justin C Lee, Sukwon Lee, Sukwoo Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100108 (2014)
Fear renewal, the context-specific relapse of fear following fear extinction, is a leading animal model of post-traumatic stress disorders (PTSD) and fear-related disorders. Although fear extinction can diminish fear responses, this effect is restric
Externí odkaz:
https://doaj.org/article/9a90e732157d408b97d606d2bfb1f8d3
Autor:
Ingie Hong, Jihye Kim, Junuk Lee, Sungmo Park, Beomjong Song, Jeongyeon Kim, Bobae An, Kyungjoon Park, Hyun Woo Lee, Seungbok Lee, Hyun Kim, Sang-Hyun Park, Khee Dong Eom, Sukwon Lee, Sukwoo Choi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24260 (2011)
It is generally believed that after memory consolidation, memory-encoding synaptic circuits are persistently modified and become less plastic. This, however, may hinder the remaining capacity of information storage in a given neural circuit. Here we
Externí odkaz:
https://doaj.org/article/53e43193ca804a119502f11558205834
Autor:
Sukwoo Choi, Sewon Park
Publikováno v:
Biochemical and Biophysical Research Communications. 525:292-297
'Fear neurons' in the basal amygdala (Ba) acquire excitatory responsiveness to conditioned stimuli (CS) after fear conditioning and are believed to encode aversive valence of conditioned fear. However, it is unclear whether identical fear conditionin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab21f509a249ecec03b339f0369183e
https://doi.org/10.1016/j.bbrc.2020.02.077
https://doi.org/10.1016/j.bbrc.2020.02.077
Autor:
Jeongyeon Kim, Sukwoon Song, Sukwoo Choi, Beomjong Song, Kyungjoon Park, Sukwon Lee, Ingie Hong, Sewon Park, Ji Hye Kim, Junghwa Lee
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
The myristoylated zeta inhibitory peptide (ZIP), which was originally developed as a protein kinase C/Mζ (PKCζ/PKMζ) inhibitor, is known to produce the loss of different forms of memories. However, ZIP induces memory loss even in the absence of PK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b349dde54c550d88368edd2771e99a16
http://europepmc.org/articles/PMC7588416
http://europepmc.org/articles/PMC7588416
Publikováno v:
Biochemical and biophysical research communications. 523(1)
Fear renewal is defined as return of the conditioned fear responses after extinction when a conditioned stimulus (CS) is given outside of the extinction context. Previously, we have suggested that extinction induces S-nitrosylation of GluA1 in the la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c03f4b98ec1822b2e705a29f6d6bc12
https://pubmed.ncbi.nlm.nih.gov/31831176
https://pubmed.ncbi.nlm.nih.gov/31831176
Publikováno v:
Biochemical and Biophysical Research Communications. 480:608-614
Mechanisms underlying delay fear conditioning in which conditioned stimuli (CS) are paired and co-terminated with unconditioned stimuli (US), have been extensively characterized, thus expanding knowledge concerning learning and memory. However, trace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583a98d935eb3a13580cb7f2330a4c9c
https://doi.org/10.1016/j.bbrc.2016.10.101
https://doi.org/10.1016/j.bbrc.2016.10.101