Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sukunath Narayanan"'
Autor:
Ganapavarapu Veera Ragh Sharma, Sanjeev Saxena, Narasimhan Kilambi, Lavanya Andiappan, C.V. Srinivasan, Gopalan Balasubramanian, Saravanakumar Natarajan, Shridhar Narayanan, Santosh L. Vishwakarma, Fakrudeen Ali Ahamed Nazumudeen, Thirunavukkarasu Sappanimuthu, Sukunath Narayanan, Sridharan Rajagopal, Saravanan Thirunavukkarasu, Shamundeeswari Sundaram, Naresh Sivaraman
Publikováno v:
Bioorganicmedicinal chemistry. 24(22)
Herein we report the synthesis, PDE-4B and TNF-α inhibitory activities of a few dibenzo[b,d]furan-1-yl-thiazole derivatives. The hydroxycyclohexanol amide derivatives 14, 18, 24, 29, 31 and 33 exhibited promising in vitro PDE-4B and TNF-α inhibitor
Autor:
Alexander H. Dalpke, Klaus Heeg,§, and, Karsten Siegmund, Sukunath Narayanan, Clemens Richert
Publikováno v:
Journal of Medicinal Chemistry. 46:5031-5044
A series of 21 phosphodiester oligodeoxyribonucleotides containing the core sequence 5'-GACGTT-3' or related control sequences were prepared and tested for their immunostimulatory effect on murine macrophages. The range of structural modifications te
Publikováno v:
Organic Letters. 5:247-250
[reaction: see text] A method is presented for the synthesis of single compounds or small combinatorial libraries of oligonucleotides with 2'-acylamido-2'-deoxyuridine residues at the 3'-terminus. Selection experiments identified the residue of anthr
Autor:
Sukunath Narayanan, Clemens Richert, Shruti Maheshwary, William H. Connors, Karsten Siegmund, Michael Printz, Matthias Riedrich
Publikováno v:
Nucleic Acids Research
Quinolones are antibacterial drugs that are thought to bind preferentially to disturbed regions of DNA. They do not fall into the classical categories of intercalators, groove binders or electrostatic binders to the backbone. We solved the 3D structu
Publikováno v:
Journal of the American Chemical Society. 126:4762-4763
A series of 5'-linked stilbene-DNA conjugates with different substituents in the distal aromatic ring of the stilbene was prepared, and the effect of the modifications on duplex stability was determined via UV-melting curves. A trimethoxystilbene der