Exploring the diverse acetylcholinesterase inhibitory potential of girinimbine: insights from in vitro assays, molecular docking, and simulation studies.

Autor: Taha MME; Health Research Center, Jazan University, P.O. Box: 114, Jazan 45142, Saudi Arabia. manalroa@yahoo.com., Khalid A; Health Research Center, Jazan University, P.O. Box: 114, Jazan 45142, Saudi Arabia. akahmed@jazanu.edu.sa., Elfatih F; Medicinal and Aromatic Plants and Traditional Medicine Research Institute, National Center for Research, P. O. Box 2404, Khartoum, Sudan. statspss@gmail.com., Mohan S; Health Research Center, Jazan University, P.O. Box: 114, Jazan 45142, Saudi Arabia. siddigroa@yahoo.com., Sukumaran SD; Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, 50603, Malaysia. shivanesri@yahoo.com., Ul-Haq Z; Dr. Panjwani Center for Molecular Medicine & Drug Research, University of Karachi, Karachi 75530, Pakistan. zaheer.qasmi@iccs.edu., Aljahdali IA; Department of Clinical Laboratory Sciences, Taif University, Taif, Saudi Arabia. Eman.a.j@hotmail.com., Oraibi O; Internal Medicine Department, Faculty of Medicine, Jazan, Jazan University, Saudi Arabia. ooraibi@jazanu.edu.sa., Oraibi B; Health Research Center, Jazan University, P.O. Box: 114, Jazan 45142, Saudi Arabia. boraibi@jazanu.edu.sa., Alfaifi HA; Pharmaceutical Care Administration (Jeddah Second Health Cluster), Ministry of Health, Jeddah, Saudi Arabia. haaalfaifi@moh.gov.sa., Alzahrani AH; Department of Pharmacology and Toxicology, College of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia. ahmalzahrani@kau.edu.sa., Farasani A; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan-45142, Saudi Arabia. aofarasani@jazanu.edu.sa., Jerah AA; Department of Surgery, College of Medicine, Jazan University, Jazan, 45142 Saudi Arabia. siddigroa@yahoo.com., Babiker YOH; ybabiker@jazanu.edu.sa., Abdelwahab SI; Health Research Center, Jazan University, P.O. Box: 114, Jazan 45142, Saudi Arabia. siddigroa@yahoo.com.

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France) [Cell Mol Biol (Noisy-le-grand)] 2024 Nov 24; Vol. 70 (10), pp. 154-160. Date of Electronic Publication: 2024 Nov 24.

Role of surface-exposed charged basic amino acids (Lys, Arg) and guanidination in insulin on the interaction and stability of insulin-insulin receptor complex.

Autor: Lee VS; Department of Chemistry, Drug Design Development Research Group, Center of Theoretical and Computational Physics (CTCP), Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: vannajan@um.edu.my., Sukumaran SD; Department of Chemistry, Drug Design Development Research Group, Center of Theoretical and Computational Physics (CTCP), Faculty of Science, University of Malaya, 50603, Kuala Lumpur, Malaysia., Tan PK; Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia., Kuppusamy UR; Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia., Arumugam B; Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: bavani@um.edu.my.

Publikováno v: Computational biology and chemistry [Comput Biol Chem] 2021 Jun; Vol. 92, pp. 107501. Date of Electronic Publication: 2021 Apr 24.

Synthesis, Biological Evaluation and Molecular Modelling of 2'-Hydroxychalcones as Acetylcholinesterase Inhibitors.

Autor: Sukumaran SD; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. shivanesri@yahoo.com., Chee CF; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. cfchee@yahoo.com.; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. cfchee@yahoo.com., Viswanathan G; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. geethaviswa@gmail.com., Buckle MJ; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. buckle@um.edu.my., Othman R; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. rozanaothman@um.edu.my., Abd Rahman N; Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. noorsaadah@um.edu.my., Chung LY; Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. chungly@um.edu.my.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2016 Jul 22; Vol. 21 (7). Date of Electronic Publication: 2016 Jul 22.

Synthesis, characterization, X-ray crystallography, acetyl cholinesterase inhibition and antioxidant activities of some novel ketone derivatives of gallic hydrazide-derived Schiff bases.

Autor: Gwaram NS; Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. nura_suleiman@siswa.um.edu.my, Ali HM, Abdulla MA, Buckle MJ, Sukumaran SD, Chung LY, Othman R, Alhadi AA, Yehye WA, Hadi AH, Hassandarvish P, Khaledi H, Abdelwahab SI

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2012 Feb 28; Vol. 17 (3), pp. 2408-27. Date of Electronic Publication: 2012 Feb 28.