Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Sukumar Kandasamy"'
Autor:
Anand Kumar, Anastasia N. Vlasova, Loic Deblais, Huang-Chi Huang, Asela Wijeratne, Sukumar Kandasamy, David D. Fischer, Stephanie N. Langel, Francine Chimelo Paim, Moyasar A. Alhamo, Lulu Shao, Linda J. Saif, Gireesh Rajashekara
Publikováno v:
BMC Gastroenterology, Vol 18, Iss 1, Pp 1-17 (2018)
Abstract Background Human rotavirus (HRV) is a major cause of viral gastroenteritis in infants; particularly in developing countries where malnutrition is prevalent. Malnutrition perturbs the infant gut microbiota leading to sub-optimal functioning o
Externí odkaz:
https://doaj.org/article/a516dedf737d4d6d951610b053a2b569
Autor:
Anastasia N. Vlasova, Francine C. Paim, Sukumar Kandasamy, Moyasar A. Alhamo, David D. Fischer, Stephanie N. Langel, Loic Deblais, Anand Kumar, Juliet Chepngeno, Lulu Shao, Huang-Chi Huang, Rosario A. Candelero-Rueda, Gireesh Rajashekara, Linda J. Saif
Publikováno v:
mSphere, Vol 2, Iss 2 (2017)
ABSTRACT Malnutrition affects millions of children in developing countries, compromising immunity and contributing to increased rates of death from infectious diseases. Rotavirus is a major etiological agent of childhood diarrhea in developing countr
Externí odkaz:
https://doaj.org/article/9291c5cc56e846e5b040c39e7bff2034
Autor:
Yuhuan Wang, Anastasia Vlasova, Daniel E Velasquez, Linda J Saif, Sukumar Kandasamy, Efrat Kochba, Yotam Levin, Baoming Jiang
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166038 (2016)
Live-attenuated oral rotavirus (RV) vaccines have lower efficacy in low income countries, and additionally are associated with a rare but severe adverse event, intussusception. We have been pursuing the development of an inactivated rotavirus vaccine
Externí odkaz:
https://doaj.org/article/201ce981a1404152a2235c426c8c9c0b
Autor:
Anastasia N Vlasova, Kuldeep S Chattha, Sukumar Kandasamy, Zhe Liu, Malak Esseili, Lulu Shao, Gireesh Rajashekara, Linda J Saif
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76962 (2013)
The effects of co-colonization with Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis Bb12 (Bb12) on 3-dose vaccination with attenuated HRV and challenge with virulent human rotavirus (VirHRV) were assessed in 4 groups of gnotobiotic (Gn) p
Externí odkaz:
https://doaj.org/article/8596b175aadf4d7eb47b97ef551898d0
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82966 (2013)
Rotaviruses (RV) are a major cause of gastroenteritis in children. Widespread vitamin A deficiency is associated with reduced efficacy of vaccines and higher incidence of diarrheal infections in children in developing countries. We established a vita
Externí odkaz:
https://doaj.org/article/463e396956454e0c8c7becb6a23ec407
Autor:
Juliet Chepngeno, Dipak Kathayat, F.C. Paim, Loic Deblais, A. Miyazaki, Gireesh Rajashekara, Sukumar Kandasamy, S.N. Langel, Linda J. Saif, Anastasia N. Vlasova, Huang-Chi Huang, Vishal Srivastava
Publikováno v:
Beneficial Microbes. 11:733-751
The low efficacy of human rotavirus (HRV) vaccines in low- and middle-income countries (LMIC) remains a major challenge for global health. Protein-calorie malnutrition (kwashiorkor) affects the gut microbiota and compromises immune development, leadi
Autor:
Linda J. Saif, Stephanie N. Langel, Emily H. Waide, Christopher K. Tuggle, Jack C. M. Dekkers, Zhongyan Lu, Kwonil Jung, Sukumar Kandasamy, Thavamathi Annamalai
Publikováno v:
Virus Research. 267:21-25
Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide. It is unclear which arm of the immune system regulates resistance to HuNoV infection. Thus, we studied the pathogenesis of human norovirus (HuNoV) in T−B−NK+ Sever
Autor:
Thavamathi, Annamalai, Zhongyan, Lu, Kwonil, Jung, Stephanie N, Langel, Christopher K, Tuggle, Jack C M, Dekkers, Emily H, Waide, Sukumar, Kandasamy, Linda J, Saif
Publikováno v:
Virus Res
Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide. It is unclear which arm of the immune system regulates resistance to HuNoV infection. Thus, we studied the pathogenesis of human norovirus (HuNoV) in T(−)B(−)NK(+)
Autor:
Anastasia N. Vlasova, Kuldeep S. Chattha, Sukumar Kandasamy, Linda J. Saif, Gireesh Rajashekara
Publikováno v:
Veterinary Immunology and Immunopathology. 172:72-84
Different probiotic strains of Lactobacillus and Bifidobacterium genera possess significant and widely acknowledged health-promoting and immunomodulatory properties. They also provide an affordable means for prevention and treatment of various infect
Publikováno v:
Veterinary Immunology and Immunopathology. 171:7-16
Toll-like receptors (TLRs), key initiators of innate immune responses, recognize antigens and are essential in linking innate and adaptive immune responses. Misrecognition and over-stimulation/expression of TLRs may contribute to the development of c