Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Sukriti Goyal"'
Autor:
Bharati Pandey, Sonam Grover, Sukriti Goyal, Anchala Kumari, Aditi Singh, Salma Jamal, Jagdeep Kaur, Abhinav Grover
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The enzyme Pantothenate synthetase (PS) represents a potential drug target in Mycobacterium tuberculosis. Its X-ray crystallographic structure has demonstrated the significance and importance of conserved active site residues including His44
Externí odkaz:
https://doaj.org/article/f1cfeaafef314c08819d16b4dfdec2f7
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Adverse drug reactions (ADRs) have become one of the primary reasons for the failure of drugs and a leading cause of deaths. Owing to the severe effects of ADRs, there is an urgent need for the generation of effective models which can accura
Externí odkaz:
https://doaj.org/article/97625a901dae49729c73b6ab9cd8dca1
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0190942 (2018)
HER-2 belongs to the human epidermal growth factor receptor (HER) family. Via different signal transduction pathways, HER-2 regulates normal cell proliferation, survival, and differentiation. Recently, it was reported that MCF10A, BT474, and MDA-MB-2
Externí odkaz:
https://doaj.org/article/41c7858cf95044e5ab48430cc310c27d
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Intrinsically disordered proteins (IDP) are a class of proteins that do not have a stable three-dimensional structure and can adopt a range of conformations playing various vital functional role. Alpha-synuclein is one such IDP which can aggregate in
Externí odkaz:
https://doaj.org/article/3bf904c46d9b4ac5821de25563dee4b5
Autor:
Sharad Verma, Sonam Grover, Chetna Tyagi, Sukriti Goyal, Salma Jamal, Aditi Singh, Abhinav Grover
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149014 (2016)
p53, a tumor suppressor protein, has been proven to regulate the cell cycle, apoptosis, and DNA repair to prevent malignant transformation. MDM2 regulates activity of p53 and inhibits its binding to DNA. In the present study, we elucidated the MDM2 i
Externí odkaz:
https://doaj.org/article/4fa140e3c910496ba42628b3fa29bda5
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129370 (2015)
Alzheimer's disease, a lethal neurodegenerative disorder that leads to progressive memory loss, is the most common form of dementia. Owing to the complexity of the disease, its root cause still remains unclear. The existing anti-Alzheimer's drugs are
Externí odkaz:
https://doaj.org/article/3230a70f7ba9494daf9c91f3267ce812
Autor:
Jaspreet Kaur Dhanjal, Anith Kumar Sreenidhi, Khushboo Bafna, Shashank Prakash Katiyar, Sukriti Goyal, Abhinav Grover, Durai Sundar
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134691 (2015)
Cyclooxygenase-2 (COX-2) produces prostaglandins in inflamed tissues and hence has been considered as an important target for the development of anti-inflammatory drugs since long. Administration of traditional non-steroidal anti-inflammatory drugs (
Externí odkaz:
https://doaj.org/article/5131bb7ddac54e64954903f7ac7c09df
Autor:
Nupur Nigam, Abhinav Grover, Sukriti Goyal, Shashank P Katiyar, Priyanshu Bhargava, Pi-Chao Wang, Durai Sundar, Sunil C Kaul, Renu Wadhwa
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138192 (2015)
Embelin, a natural quinone found in the fruits of Embelia ribes, is commonly used in Ayurvedic home medicine for a variety of therapeutic potentials including anti-inflammation, anti-fever, anti-bacteria and anti-cancer. Molecular mechanisms of these
Externí odkaz:
https://doaj.org/article/932509f6220b46dc825bfc72234babf3
Publikováno v:
Advances in Computing Communications and Informatics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32bb3a9fa531a8df71dc29a0bfd2ce1f
https://doi.org/10.2174/9781681088624121010008
https://doi.org/10.2174/9781681088624121010008
Publikováno v:
Data Analytics and Management ISBN: 9789811583346
With the frequent growth in smartphones and media tablets, the industry of computer systems captured leadership from the industry of telecommunication in carry forwarding technological evolution. However, the principal component impacting the growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd565d66a15bbc4a458ef2256fd61e04
https://doi.org/10.1007/978-981-15-8335-3_7
https://doi.org/10.1007/978-981-15-8335-3_7