Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sukjin Yang"'
Autor:
Dayong Zheng, Yan Zhang, Sukjin Yang, Ning Su, Michael Bakhoum, Guoliang Zhang, Samira Naderinezhad, Zhengmei Mao, Zheng Wang, Ting Zhou, Wenliang Li
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Although effective initially, prolonged androgen deprivation therapy (ADT) promotes neuroendocrine differentiation (NED) and prostate cancer (PCa) progression. It is incompletely understood how ADT transcriptionally induces NE genes in PCa c
Externí odkaz:
https://doaj.org/article/90b69f9b55bf4bdc9486b4db44b5ad47
Publikováno v:
Cancer Research. 83:P6-11
Historically known as a tumor suppressor by estrogen receptor (ER) co-repression in breast cancer (BC), the matrix binding protein Scaffold Attachment Factor B1 (SAFB) binds scaffold or matrix attachment region DNA elements (S/MAR DNA) in eukaryotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8383a4c99a7f571857bd09f25747a1b
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-01
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-01
Publikováno v:
Cancer Research. 83:P6-11
Breast cancer stem cell (BCSC) is a subset of cancer cells that can dictate the tumor initiation, metastatic progression, and therapeutic resistance in BC. The eradication of this unusual population is emerging as a new paradigm in cancer treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a2ac1b43fbad92eee9a06204829257b
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-11
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-11
Publikováno v:
Cancer Research. 83:P6-11
Compared to hormone receptor (HR) positive breast cancer (BC), basal or triple-negative BC (TNBC) suffers a poor prognosis caused by a limited understanding of its driver signaling pathways. We used the transmitochondrial cybrid approach to understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c94144fe469a04bc01784ee30de0efcb
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-02
https://doi.org/10.1158/1538-7445.sabcs22-p6-11-02
Autor:
Jun Hyoung Park, Herbert Levine, Shubham Tripathi, Youyuan Deng, Kwang Hwa Jung, Dongya Jia, Benny Abraham Kaipparettu, José N. Onuchic, Harsimran Kaur, Mohit Kumar Jolly, Sukjin Yang, Madeline Galbraith
Publikováno v:
Br J Cancer
Cancer cells have the plasticity to adjust their metabolic phenotypes for survival and metastasis. A developmental programme known as epithelial-to-mesenchymal transition (EMT) plays a critical role during metastasis, promoting the loss of polarity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ab999f5c95fd51666dd29ebf706b15
https://doi.org/10.1038/s41416-021-01385-y
https://doi.org/10.1038/s41416-021-01385-y
Autor:
Junhyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S. Attri, Songyeon Ahn, Divya Murthy, Meron Ghidey, Somik Chatterjee, Diego A. Pedroza, Abha Tiwari, Suna Kim, Chad C. Creighton, Nagireddy Putluri, Jeffrey M. Rosen, José N. Onuchic, Andrei Goga, Benny A. Kaipparettu
Publikováno v:
Cancer Research. 83:294-294
Biguanides such as metformin are one of the most widely administered anti-diabetic drugs. Biguanides can suppress OXPHOS by inhibiting the complex-I activity of the mitochondrial electron transport chain (ETC). Though metformin recently generated lot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bda6b7e873d60ad146423d88c53ae86
https://doi.org/10.1158/1538-7445.am2023-294
https://doi.org/10.1158/1538-7445.am2023-294
Autor:
H. Carl Lekaye, Changyuan Lu, Jatin Roper, Lewis C. Cantley, Kyu Y. Rhee, Justin M. Van Riper, Young Ho Kim, Qiuying Chen, Chantal Pauli, Roxanne Morris, Charles J. Murphy, Jordan Tutnauer, Kaitlyn Bosch, Marcus D. Goncalves, Seo-Kyoung Hwang, Yumei Wang, Sukjin Yang, Samuel Taylor, Jihye Yun, Travis Hartman, Steven S. Gross
Publikováno v:
Science. 363:1345-1349
A sweetener's not-so-sweet effects Obesity increases an individual's risk of developing many types of cancer, including colorectal cancer. One of the factors driving the rise in obesity rates is thought to be the use of high-fructose corn syrup (HFCS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04858bd1cbebe122c2a3091a77cbd32b
https://doi.org/10.1126/science.aat8515
https://doi.org/10.1126/science.aat8515
Autor:
Gokul M. Das, Chetan C. Oturkar, Christina Adams, Jung H. Park, Melissa Dolan, Michalis Mastri, Manasori Oshi, Yoshihisa Tokumaru, Utpal K. Mukhopadhyay, Kalyani Abha, Kwang H. Jung, Sukjin Yang, Suna Kim, John Ebos, Kazuaki Takabe, Benny A. Kaipparettu
Publikováno v:
Cancer Research. 82:3986-3986
Triple-negative breast cancer (TNBC) is an aggressive subtype without any effective targeted therapies and rapidly become resistant to generic chemotherapy. Therefore, there is an urgent need to develop new therapeutic strategies. Estrogen receptor b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58df593e1b0290668b72c0e2f4b755fa
https://doi.org/10.1158/1538-7445.am2022-3986
https://doi.org/10.1158/1538-7445.am2022-3986
Autor:
Eun-Jeong Jeong, Mijin Park, Seong-Min Park, Kyu Sang Song, Young Il Yeom, Jung-Ae Kim, Byul Moon, Sukjin Yang, Jang-Seong Kim, Sang-Hyun Lee
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
BMC Cancer
BMC Cancer
Background Anchoring filament protein ladinin-1 (LAD1) was related to the aggressive progression of breast, lung, laryngeal and thyroid cancers. However, the association of LAD1 with colorectal cancer remained unknown. Here, to determine the relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b63b2dda2c24205e9aaca3da97632a
https://doi.org/10.1186/s12885-020-07660-0
https://doi.org/10.1186/s12885-020-07660-0
Autor:
Jun Hyoung Park, Dongya Jia, Sukjin Yang, Kwang Hwa Jung, Abha Tiwari, Debasmita Dutta, Meron Ghidey, Nagireddy Putluri, Cristian Coarfa, Chad Creighton, José N. Onuchic, Benny A Kaipparettu
Publikováno v:
Cancer Research. 82:P5-05
We have previously reported that triple negative (TN) breast cancer (BC), an aggressive subtype of BC, has high dependency for mitochondrial fatty acid oxidation (FAO). We have also reported that FAO activates c-Src, one of the frequently upregulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23944bf403513b5455ad8a8a3128d413
https://doi.org/10.1158/1538-7445.sabcs21-p5-05-06
https://doi.org/10.1158/1538-7445.sabcs21-p5-05-06