Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sukhdev Roy"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Vision restoration is one of the most promising applications of optogenetics. However, it is limited due to the poor-sensitivity, slow-kinetics and narrow band absorption spectra of opsins. Here, a detailed theoretical study of retinal gangl
Externí odkaz:
https://doaj.org/article/8f748d89ccbd44a29e318c5e5ae21b9e
Publikováno v:
Photonics, Vol 10, Iss 5, p 571 (2023)
The fundamental process of information processing and memory formation in the brain is associated with complex neuron firing patterns, which can occur spontaneously or be triggered by sensory inputs. Optogenetics has revolutionized neuroscience by en
Externí odkaz:
https://doaj.org/article/b591bab87fbd43f68f1093b48f7ba23a
Autor:
Sukhdev Roy
Publikováno v:
Papers in Physics, Vol 2, Iss 0, p 020011 (2010)
A Commentary on the paper by H. E. Grecco and O. E. Martinez [Pap. Phys. 2, 020010 (2010)].Received: 13 July 2010, Accepted: 10 January 2011; Edited by: V. Lakshminarayanan; DOI: 10.4279/PIP.020011
Externí odkaz:
https://doaj.org/article/4aa2ce31ac5c484cb80a918182fd0627
Publikováno v:
The Journal of physiologyReferences. 600(21)
The main challenge in cardiac optogenetics is to have low-power, high-fidelity deep excitation of cells with minimal invasiveness and heating. We present a detailed computational study of optogenetic excitation of human ventricular cardiomyocytes (HV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c718b0bd7e9a184292ee25097e9320
https://pubmed.ncbi.nlm.nih.gov/36068951
https://pubmed.ncbi.nlm.nih.gov/36068951
Publikováno v:
Neuroscience. 449:165-188
Low-power and high-frequency bidirectional control of spatiotemporal patterns of neural spiking is one of the major challenges in optogenetics. A detailed theoretical analysis and optimization with ChR2-NpHR, ChR2(H134R)-eNpHR3.0, Chrimson-GtACR2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df05b7e15874565556ddb4fd12a550e8
https://doi.org/10.1016/j.neuroscience.2020.09.022
https://doi.org/10.1016/j.neuroscience.2020.09.022
Publikováno v:
Biomedical physicsengineering express. 6(4)
A detailed theoretical analysis of low-power, high-frequency and temporally precise optogenetic inhibition of neuronal spiking, with red-shifted opsins namely, NpHR, eNpHR3.0 and Jaws, has been presented. An accurate model for inhibition of spiking i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617e5786129fec447a23ed2ef30e3116
https://pubmed.ncbi.nlm.nih.gov/33444272
https://pubmed.ncbi.nlm.nih.gov/33444272
Publikováno v:
Journal of Neural Engineering. 19:026032
Objective. A fundamental challenge in optogenetics is to elicit long-term high-fidelity neuronal spiking with negligible heating. Fast channelrhodopsins (ChRs) require higher irradiances and cause spike failure due to photocurrent desensitization und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cc876f1d64ac92c4307f2d408be045
https://doi.org/10.1088/1741-2552/ac6061
https://doi.org/10.1088/1741-2552/ac6061
Publikováno v:
Journal of neural engineering. 18(4)
Objective.Optogenetics has emerged as a promising technique for neural prosthetics, especially retinal prostheses, with unprecedented spatiotemporal resolution. Newly discovered opsins with high light sensitivity and fast temporal kinetics can provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a89454b1964b5a163b9f532bc6721a
https://pubmed.ncbi.nlm.nih.gov/34229315
https://pubmed.ncbi.nlm.nih.gov/34229315
Publikováno v:
Optik. 243:167344
A detailed theoretical analysis of spiking dynamics of VCSEL-SA based Photonic Laser Neuron (PLN) has been presented, under continuous and pulsed current injection. The maximum output spiking frequency of laser neuron is 9 GHz on continuous input cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db1269d4b2fd8c99a89ae2d6f3edcd9e
https://doi.org/10.1016/j.ijleo.2021.167344
https://doi.org/10.1016/j.ijleo.2021.167344
Publikováno v:
Neurophotonics. 6(2)
A detailed theoretical analysis and optimization of high-fidelity, high-frequency firing of the red-shifted very-fast-Chrimson (vf-Chrimson) expressing neurons is presented. A four-state model for vf-Chrimson photocycle has been formulated and incorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482c01802584f4d00679be12940f989d
https://pubmed.ncbi.nlm.nih.gov/31001567
https://pubmed.ncbi.nlm.nih.gov/31001567