Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sukhanya Jayachandra"'
Publikováno v:
BioTechniques, Vol 21, Iss 3, Pp 472-480 (1996)
A long PCR method was developed for the efficient site-specific mutagenesis of herpes simplex virus (HSV-1) DNA fragments with high GC content. In this protocol, a PCR product was partially extended first using a cloned DNA fragment. The final mutage
Externí odkaz:
https://doaj.org/article/15f00db2d36e42a8abe2cd144bd049dc
Autor:
David Connors, Andrew Bullen, Lauren Barber, Christopher Bernard, Sukhanya Jayachandra, Angela Cacace
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 9:209-217
The design and implementation of an automated tissue culture flask labeling, delivery, scraping, and retrieval system centered around the CellmateTm cell culture robot is presented. Three new custom subsystems named FlaskMaster, FlaskLabeler, and Fla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3603e84724209df50bdd070516ab8fde
https://doi.org/10.1016/j.jala.2004.03.004
https://doi.org/10.1016/j.jala.2004.03.004
Autor:
Jonathan O’Connell, Martyn Banks, Jenny Xie, John Watson, Neil T. Burford, Mary Ellen Cvijic, Alaric J. Dyckman, Andrew Alt, Mengjie Chen, Yingjie Zhu, Andrea D. Weston, Sukhanya Jayachandra, Litao Zhang, Michele Agler, Ding Ren Shen, Melissa Yarde
Publikováno v:
Journal of biomolecular screening. 19(7)
G protein-coupled receptors (GPCRs) are one of the most popular and proven target classes for therapeutic intervention. The increased appreciation for allosteric modulation, receptor oligomerization, and biased agonism has led to the development of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b22b3424eedb273233dc5db6d39c25
https://pubmed.ncbi.nlm.nih.gov/24789006
https://pubmed.ncbi.nlm.nih.gov/24789006
Autor:
Yuan Chang, Robin A. Weiss, Patrick S. Moore, Chris Boshoff, Shou-Jiang Gao, Sukhanya Jayachandra
Publikováno v:
Scopus-Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV) is a gammaherpesvirus linked to the development of Kaposi's sarcoma and a rare B cell lymphoma, primary effusion lymphoma. The KSHV gene ORF K9 encodes vIRF which is a protein with low but significant ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e877a2aba5060509daaf9962d2d3ff
https://doi.org/10.1038/sj.onc.1201571
https://doi.org/10.1038/sj.onc.1201571
Publikováno v:
Journal of Virology. 71:5012-5024
We characterized the glycoprotein K (gK)-null herpes simplex virus type 1 [HSV-1] (KOS) delta gK and compared it to the gK-null virus HSV-1 F-gKbeta (L. Hutchinson et al., J. Virol. 69:5401-5413, 1995). delta gK and F-gKbeta mutant viruses produced s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3827670663c4f3b28eb99a3bdc6490da
https://doi.org/10.1128/jvi.71.7.5012-5024.1997
https://doi.org/10.1128/jvi.71.7.5012-5024.1997
Publikováno v:
Journal of Virology. 67:2396-2401
Three amber mutations were introduced proximal to the syn3 locus of the herpes simplex virus type 1 glycoprotein B (gB) gene specifying gB derivatives lacking the carboxy-terminal 28, 49, or 64 amino acids. A complementation system that utilized gBs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625e342bf3e55bd9d187b05eeba29fff
https://doi.org/10.1128/jvi.67.4.2396-2401.1993
https://doi.org/10.1128/jvi.67.4.2396-2401.1993
Autor:
Yang Wu, Umesh Hanumegowda, Stephen P. Adams, Sukhanya Jayachandra, Lauren Barber, David Connors
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 23(6)
Proximal tubules of the kidneys are one of the most common targets of nephrotoxic drugs and chemicals. Screens to predict nephrotoxic potential of compounds with insights to mechanisms of toxicity facilitate lead optimization, guide structure-activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014703e489a300abfada023723219734
https://pubmed.ncbi.nlm.nih.gov/19523510
https://pubmed.ncbi.nlm.nih.gov/19523510
Autor:
John P. Corradi, Jeremy H. Toyn, C.V.C. Prasad, Richard E. Olson, Vanessa Hay, Barbara J. Robertson, Lynn A. Balanda, Robert Zaczek, Lawrence G. Iben, Charles F. Albright, Sukhanya Jayachandra
Publikováno v:
The Journal of biological chemistry. 282(51)
The enzyme gamma-secretase has long been considered a potential pharmaceutical target for Alzheimer disease. Presenilin (the catalytic subunit of gamma-secretase) and signal peptide peptidase (SPP) are related transmembrane aspartyl proteases that cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0107c18b1e7f752c7f3408231a60a28f
https://pubmed.ncbi.nlm.nih.gov/17932033
https://pubmed.ncbi.nlm.nih.gov/17932033
Autor:
Paul D. Ling, Sukhanya Jayachandra, Ai-En Thlick, Jin Yu, Kenneth G. Low, Patrick S. Moore, Yuan Chang
Kaposi sarcoma-associated herpesvirus vIRF is a viral transcription factor that inhibits interferon signaling and transforms NIH 3T3 cells, but does not bind interferon-stimulated response element (ISRE) DNA sequences. Here we show that induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfff34d0297ec6b5fa036934bb862dba
https://europepmc.org/articles/PMC18074/
https://europepmc.org/articles/PMC18074/
Publikováno v:
BioTechniques. 21(3)
A long PCR method was developed for the efficient site-specific mutagenesis of herpes simplex virus (HSV-1) DNA fragments with high GC content. In this protocol, a PCR product was partially extended first using a cloned DNA fragment. The final mutage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebc3bea462e2fec11599fa576169494
https://pubmed.ncbi.nlm.nih.gov/8879587
https://pubmed.ncbi.nlm.nih.gov/8879587