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Akademický článek

Pharmacokinetics, Urinary Excretion, and Pharmaco-Metabolomic Study of Tebipenem Pivoxil Granules After Single Escalating Oral Dose in Healthy Chinese Volunteers

Autor: Zeyun Li, Mei Su, Weiyan Cheng, Jueyu Xia, Shuaibing Liu, Ruijuan Liu, Suke Sun, Luyao Feng, Xueya Zhu, Xiaojian Zhang, Xin Tian, Lingbo Qu

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Tebipenem pivoxil (TBPM-PI), an oral carbapenem antibiotic, has shown special advantages in pediatric infections and was in urgent need in China. Although pharmacokinetics, urinary excretion, and metabolite information of its active form tebipenem (T

Externí odkaz: https://doaj.org/article/fabd6d0b03304c5ea0eb71e32754d895

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Role of programmed death ligands in effective T-cell interactions in extranodal natural killer/T-cell lymphoma

Autor: Zhaoming Li, Lijuan Han, Zhiyuan Zhou, Jianguo Wen, Tengpeng Hu, Xinfeng Chen, Ken Young, Ruping Li, Xudong Zhang, Mingzhi Zhang, Suke Sun, Feifei Liu, Yi Zhang

Publikováno v: Oncology Letters

Extranodal natural killer/T-cell lymphoma (ENKL) is marked by a profound cellular immune deficiency that may influence the capacity of T cells to extract an efficient antitumor immune response. It has been confirmed that the B7-CD28 pathway may promo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e7ff619401cd742e29e5d3fa187036
http://europepmc.org/articles/PMC4156194

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Association of p21 3' UTR gene polymorphism with cancer risk: Evidence from a meta-analysis

Autor: Zhenzhen Li, Suyun Wang, Jie Li, Quancheng Kan, Suke Sun, Yidong Li

Publikováno v: Scientific Reports

Numerous studies have investigated the risk of cancer associated with the polymorphism of p21 3′ UTR (rs1059234 C > T), but results have been inconsistent. We performed this meta-analysis to drive a more precise estimation of the association betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a83b04ab57fbe5d41b104491c49aaa
https://pubmed.ncbi.nlm.nih.gov/26278624

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Pilot and pivotal study to evaluate the bioequivalence of two paroxetine 40 mg tablet formulations in healthy Chinese subjects

Autor: Jianguo Wen, Li Yang, Yidong Li, Jie Zhao, Feng Zhang, Wenzhe Lv, Quancheng Kan, Yuanchao Derek Zhang, Zhongping John Lin, Kun Qian, Shengjun Zhang, Yuqiao Sheng, Suke Sun

Publikováno v: International journal of clinical pharmacology and therapeutics. 50(7)

The purpose of this study was to conduct a pilot study in order to obtain reliable results for further planning of a well-designed pivotal trial comparing the bioequivalence (BE) of two paroxetine tablet formulations in healthy Chinese subjects. Befo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894efd4114028f918c4db2e00da6690c
https://pubmed.ncbi.nlm.nih.gov/22541747

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