The clinical relevance of persistent recombinant immunoblot assay-indeterminate reactions: insights into the natural history of hepatitis C virus infection and implications for donor counseling

Autor: Peter D. Burbelo, Addisalem T. Makuria, Joan Gibble, Robert D. Allison, Barbara Rehermann, Sukanya Raghuraman, Harvey J. Alter, Cathy Cantilena

Publikováno v: Transfusion. 52:1940-1948

BACKGROUND: Recombinant immunoblot assay (RIBA) is used to determine the specificity of antibody to hepatitis C virus (anti-HCV). The RIBA result is recorded as positive, negative, or indeterminate. The interpretation and significance of RIBA-indeter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24275b6e51df09c7b92c289f35cfd6b4
https://doi.org/10.1111/j.1537-2995.2011.03524.x

Distribution of the different genotypes of HCV among patients attending a tertiary care hospital in south India

Autor: Balakrishnan S. Ramakrishna, Gopalan Sridharan, S. Radhakrishnan, George Chandy, Priya Abraham, Sukanya Raghuraman, Ramachandran V Shaji

Publikováno v: Journal of Clinical Virology. 26:61-69

Background: Genotyping of the hepatitis C virus (HCV) and assessment of viral load is important for designing therapeutic strategies and region specific diagnostic assays. Objectives: To determine the distribution of HCV genotypes among patients atte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a826536c8a29f5c975b805949abbf381
https://doi.org/10.1016/s1386-6532(02)00025-2

Persistent infectious diseases say - IDO. Role of indoleamine-2,3-dioxygenase in disease pathogenesis and implications for therapy

Autor: Sukanya Raghuraman, Heidi Barth

Publikováno v: Critical Reviews in Microbiology
Critical Reviews in Microbiology, Taylor & Francis, 2014, 40 (4), pp.360-368. ⟨10.3109/1040841x.2012.742037⟩

Indoleamine-2,3-dioxygenase (IDO) is an enzyme that catabolises tryptophan – an essential amino acid critical for T cell proliferation. Initially recognized as a first line of host defense against infectious pathogens, IDO has been subsequently ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef489303065d01a55397e5b7736b9a5
https://hal.archives-ouvertes.fr/hal-03070740

Comparison of Three Different Hepatitis C Virus Genotyping Methods: 5′NCR PCR-RFLP, Core Type-Specific PCR, and NS5b Sequencing in a Tertiary Care Hospital in South India

Autor: Manu Gnanamony, Sukanya Raghuraman, Joel David, George Chandy, Priya Abraham, Gopalan Sridharan, Hubert Darius J. Daniel

Publikováno v: Journal of Clinical Laboratory Analysis. 31:e22045

Background Based on genetic heterogeneity, hepatitis C virus (HCV) is classified into seven major genotypes and 64 subtypes. In spite of the sequence heterogeneity, all genotypes share an identical complement of colinear genes within the large open r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bcb431c5569bb2e5ab11b1b0db5115
https://doi.org/10.1002/jcla.22045

B-cell Homeostasis in Chronic Hepatitis C Virus-Related Mixed Cryoglobulinemia is Maintained Through Naïve B-cell Apoptosis

Autor: Michael C. Sneller, Barbara Rehermann, Lauren E. Holz, Susan Moir, Sukanya Raghuraman, Joo Chun Yoon

Mixed cryoglobulinemia (MC) is the most common extrahepatic manifestation of chronic hepatitis C virus (HCV) infection. Although the formation of inflammation-triggering immune complexes is driven by clonal expansions of autoreactive B cells, we foun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d5fb3dbe83198d7735023b1182bbbe
https://europepmc.org/articles/PMC3421034/