Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sukanya Chumchuen"'
Autor:
Amornrat Tangprasittipap, Pawarit Innachai, Sukanya Chumchuen, Wararat Chiangjong, Natini Jinawath, Nongnuch Sirachainan, Suradej Hongeng
Publikováno v:
Stem Cell Research, Vol 79, Iss , Pp 103474- (2024)
Ten-Eleven Translocation methylcytosine dioxygenase 1 (TET1) is known to play a broad tumor suppressor role through demethylating and activating tumor suppressor genes. TET1 missense mutations are previously reported in many types of leukemia. Here,
Externí odkaz:
https://doaj.org/article/e13dd971704f41848e0ee89483288582
Autor:
Chokdee Wongborisuth, Sukanya Chumchuen, Orapan Sripichai, Usanarat Anurathaphan, Nuankanya Sathirapongsasuti, Duantida Songdej, Amornrat Tangprasittipap, Suradej Hongeng
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Reactivating of fetal hemoglobin (HbF; α2γ2) can ameliorate the severity of β-thalassemia disease by compensating for adult hemoglobin deficiency in patients. Previously, microarray analysis revealed that zinc finger protein (ZNF)802 (als
Externí odkaz:
https://doaj.org/article/5be5abf3bdcf4e058589c3c34b0fffe1
Autor:
Sukanya Chumchuen, Orapan Sripichai, Natee Jearawiriyapaisarn, Suthat Fucharoen, Chayanon Peerapittayamongkol
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0281059 (2023)
Imbalanced globin chain output contributes to thalassemia pathophysiology. Hence, induction of fetal hemoglobin in β-thalassemia and other β-hemoglobinopathies are of continuing interest for therapeutic approaches. Genome-wide association studies h
Externí odkaz:
https://doaj.org/article/8e464e9501f443a9a400fe86ec02f049
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102675- (2022)
MUi028-A human induced pluripotent stem cell (hiPSC) line was generated from normal fetal skin fibroblasts using a non-integrative reprogramming method. Reprogramming factors OCT4, SOX2, KLF4, L-MYC, and LIN28, and TP53 shRNA in three episomal vector
Externí odkaz:
https://doaj.org/article/c5f3f6cb9ac94d89a2eaa0136d449913
Autor:
Amornrat Tangprasittipap, Sukanya Chumchuen, Gunn Pornratananont, Narisorn Kitiyanant, Suradej Hongeng
Publikováno v:
Stem Cell Research, Vol 52, Iss , Pp 102211- (2021)
The 13q deletion syndrome is a rare chromosomal disorder caused by loss of the long arm of chromosome 13, and usually entails developmental delay, intellectual disability, behavioral problems and distinctive facial features. In this study, we success
Externí odkaz:
https://doaj.org/article/70882109b6424516b536346b49a40734
Autor:
Chokdee Wongborisuth, Sukanya Chumchuen, Orapan Sripichai, Usanarat Anurathaphan, Nuankanya Sathirapongsasuti, Duantida Songdej, Amornrat Tangprasittipap, Suradej Hongeng
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/cab3ea3f1c42469cb010fb22b9c47ad0
Autor:
Thunwarat Suriyun, Woratree Kaewsakulthong, Orapan Sripichai, Sukanya Chumchuen, Suradej Hongeng, Suthat Fucharoen, Pinyaphat Khamphikham
Publikováno v:
Acta Haematologica. 144:660-671
Introduction: β-Thalassemia/hemoglobin E represents one-half of all the clinically severe β-thalassemias worldwide. Despite similar genetic backgrounds, patients show clinical heterogeneity ranging from nearly asymptomatic to transfusion-dependent
Publikováno v:
Stem Cell Research, Vol 60, Iss, Pp 102675-(2022)
MUi028-A human induced pluripotent stem cell (hiPSC) line was generated from normal fetal skin fibroblasts using a non-integrative reprogramming method. Reprogramming factors OCT4, SOX2, KLF4, L-MYC, and LIN28, and TP53 shRNA in three episomal vector
Autor:
Chokdee, Wongborisuth, Sukanya, Chumchuen, Orapan, Sripichai, Usanarat, Anurathaphan, Nuankanya, Sathirapongsasuti, Duantida, Songdej, Amornrat, Tangprasittipap, Suradej, Hongeng
Publikováno v:
Scientific reports. 12(1)
Reactivating of fetal hemoglobin (HbF; α2γ2) can ameliorate the severity of β-thalassemia disease by compensating for adult hemoglobin deficiency in patients. Previously, microarray analysis revealed that zinc finger protein (ZNF)802 (also known a
Autor:
Woratree Kaewsakulthong, Thunwarat Suriyun, Sukanya Chumchuen, Usanarat Anurathapan, Suradej Hongeng, Suthat Fucharoen, Orapan Sripichai
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 18; Pages: 5356
Defective hemoglobin production and ineffective erythropoiesis contribute to the pathophysiology of thalassemia syndromes. Previous studies in the field of erythropoiesis mainly focused on the severe forms of thalassemia, such as β-thalassemia major