Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Sukanya, Narasimhan"'
Autor:
Sukanya Narasimhan, Nallakkandi Rajeevan, Morven Graham, Ming-Jie Wu, Kathleen DePonte, Solenne Marion, Orlanne Masson, Anya J. O’Neal, Joao H. F. Pedra, Daniel E. Sonenshine, Erol Fikrig
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Ixodes scapularis is the predominant tick vector of Borrelia burgdorferi, the agent of Lyme disease, in the USA. Molecular interactions between the tick and B. burgdorferi orchestrate the migration of spirochetes from the midgut t
Externí odkaz:
https://doaj.org/article/4654c8393ab74cbdb11c666caf8a7d85
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Ixodes scapularis is one of the predominant vectors of Borrelia burgdorferi, the agent of Lyme disease in the USA. The geographic distribution of I. scapularis, endemic to the northeastern and northcentral USA, is expanding as far south as Georgia an
Externí odkaz:
https://doaj.org/article/c911a877ee9a4a9d9f9a787ddebf4f48
Autor:
Jos J. A. Trentelman, Julen Tomás-Cortázar, Sarah Knorr, Diego Barriales, Ondrej Hajdusek, Radek Sima, Jasmin I. Ersoz, Sukanya Narasimhan, Erol Fikrig, Ard M. Nijhof, Juan Anguita, Joppe W. Hovius
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract In Europe, Ixodes ricinus is the most important vector of human infectious diseases, most notably Lyme borreliosis and tick-borne encephalitis virus. Multiple non-natural hosts of I. ricinus have shown to develop immunity after repeated tick
Externí odkaz:
https://doaj.org/article/aecc1fe1ce21426d9843e8b3495ae2c8
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/e66e1aaabea247a69215f0174c99ab60
Autor:
Xiaotian Tang, Yongguo Cao, Gunjan Arora, Jesse Hwang, Andaleeb Sajid, Courtney L Brown, Sameet Mehta, Alejandro Marín-López, Yu-Min Chuang, Ming-Jie Wu, Hongwei Ma, Utpal Pal, Sukanya Narasimhan, Erol Fikrig
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/581d61f055b44e5398e2fcc261538404
Publikováno v:
Pathogens, Vol 12, Iss 1, p 132 (2023)
The blacklegged tick, Ixodes scapularis, is the predominant vector of Borrelia burgdorferi, the agent of Lyme disease in the USA. Natural hosts of I. scapularis such as Peromyscus leucopus are repeatedly infested by these ticks without acquiring tick
Externí odkaz:
https://doaj.org/article/fe9144a3b7884ad9b0f0463793697ee7
Autor:
Xiaotian Tang, Yongguo Cao, Gunjan Arora, Jesse Hwang, Andaleeb Sajid, Courtney L Brown, Sameet Mehta, Alejandro Marín-López, Yu-Min Chuang, Ming-Jie Wu, Hongwei Ma, Utpal Pal, Sukanya Narasimhan, Erol Fikrig
Publikováno v:
eLife, Vol 10 (2021)
Adiponectin-mediated pathways contribute to mammalian homeostasis; however, little is known about adiponectin and adiponectin receptor signaling in arthropods. In this study, we demonstrate that Ixodes scapularis ticks have an adiponectin receptor-li
Externí odkaz:
https://doaj.org/article/a44fd9503ecd448a8e723336d1c6c5fc
Autor:
Sukanya Narasimhan, Tim J. Schuijt, Nabil M. Abraham, Nallakkandi Rajeevan, Jeroen Coumou, Morven Graham, Andrew Robson, Ming-Jie Wu, Sirlei Daffre, Joppe W. Hovius, Erol Fikrig
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Borrelia burgdorferi, the causative agent of Lyme disease, is transmitted by the tick Ixodes scapularis. Here, the authors show that a tick secreted protein (PIXR) modulates the tick gut microbiota and facilitates B. burgdorferi colonization.
Externí odkaz:
https://doaj.org/article/f8125e0a31f24597bc975085a2deecbb
Autor:
Anya J. O’Neal, Nisha Singh, Agustin Rolandelli, Hanna J. Laukaitis, Xiaowei Wang, Dana K. Shaw, Brianna D. Young, Sukanya Narasimhan, Shraboni Dutta, Greg A. Snyder, Sourabh Samaddar, Liron Marnin, L. Rainer Butler, M. Tays Mendes, Francy E. Cabrera Paz, Luisa M. Valencia, Eric J. Sundberg, Erol Fikrig, Utpal Pal, David J. Weber, Joao H. F. Pedra
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e058ce38e5f57725218a3f90eac7492
https://doi.org/10.1073/pnas.2208673120
https://doi.org/10.1073/pnas.2208673120
Autor:
Vipin S. Rana, Chrysoula Kitsou, Shraboni Dutta, Michael H. Ronzetti, Min Zhang, Quentin Bernard, Alexis A. Smith, Julen Tomás-Cortázar, Xiuli Yang, Ming-Jie Wu, Oleksandra Kepple, Weizhong Li, Jennifer E. Dwyer, Jaqueline Matias, Bolormaa Baljinnyam, Jonathan D. Oliver, Nallakkandi Rajeevan, Joao H F Pedra, Sukanya Narasimhan, Yan Wang, Ulrike Munderloh, Erol Fikrig, Anton Simeonov, Juan Anguita, Utpal Pal
Publikováno v:
Science. 379
Ancestral signaling pathways serve critical roles in metazoan development, physiology, and immunity. We report an evolutionary interspecies communication pathway involving a central Ixodes scapularis tick receptor termed Dome1, which acquired a mamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb3c00cd79e58462333434ad827df7e
https://doi.org/10.1126/science.abl3837
https://doi.org/10.1126/science.abl3837