Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Suk Ying, Tsang"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Background Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdevelope
Externí odkaz:
https://doaj.org/article/b736361c07044f5da99680857c9d2df7
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background Biological pacemakers consisting of pluripotent stem cell-derived cardiomyocytes are potentially useful for treating bradycardia. However, tachyarrhythmia caused by derived cardiomyocytes themselves is one of main barriers hamperi
Externí odkaz:
https://doaj.org/article/9ef85e57380d41d8bb8b21554d6d0365
Autor:
Zenghua Qi, Tao Wang, Xiangmao Chen, Chun Kit Wong, Qianqian Ding, Heinrich Sauer, Zhi-Feng Chen, Cheng Long, Xiaoqiang Yao, Zongwei Cai, Suk Ying Tsang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Angiotensin II (Ang II) plays an important role in regulating various physiological processes. However, little is known about the existence of intracellular Ang II (iAng II), whether iAng II would regulate the automaticity of early differentiating ca
Externí odkaz:
https://doaj.org/article/dfa632cd98cb4d549096d4144c73b68e
PinX1t, a Novel PinX1 Transcript Variant, Positively Regulates Cardiogenesis of Embryonic Stem Cells
Autor:
Hing Chung Chan, Yuen Ting Lau, Qianqian Ding, Chun Kit Li, Chi Ming Wong, Pang Chui Shaw, Mary Miu Yee Waye, Suk Ying Tsang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 6 (2020)
Background Pin2/TRF1‐interacting protein, PinX1, was previously identified as a tumor suppressor. Here, we discovered a novel transcript variant of mPinX1 (mouse PinX1), mPinX1t (mouse PinX1t), in embryonic stem cells (ESCs). The aims of this inves
Externí odkaz:
https://doaj.org/article/f3729d305b434aa19e9980952ce2661a
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 3, Pp 295-303 (2018)
It has long been a puzzle in cancer treatment that despite the initial appearance of apoptosis, the process could be reversed in some cancer cells and often results in more aggressive tumors and metastasis. The mechanism for this recurrence is yet un
Externí odkaz:
https://doaj.org/article/ee549c45cc8d4565ab40ae86617758fb
Publikováno v:
Cells, Vol 10, Iss 9, p 2463 (2021)
Pluripotent stem cells (PSCs) can undergo unlimited self-renewal and can differentiate into all the cell types present in our body, including cardiomyocytes. Therefore, PSCs can be an excellent source of cardiomyocytes for future regenerative medicin
Externí odkaz:
https://doaj.org/article/71b75bccb29c4c6c8cfb9093e4805473
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Externí odkaz:
https://doaj.org/article/da3ac124e8094c24ad8b106c224f0af7
Autor:
Eunice Yuen Ting Lau, Jessica Lo, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Joyce Man Fong Lee, Johnson Kai Yu Ng, Stella Chai, Chi Ho Lin, Suk Ying Tsang, Stephanie Ma, Irene Oi Lin Ng, Terence Kin Wah Lee
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1175-1189 (2016)
Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesize
Externí odkaz:
https://doaj.org/article/3cdc6d5ccfb249248e8b45a87e42a838
Publikováno v:
Cells, Vol 9, Iss 1, p 135 (2020)
Transient Receptor Potential Canonical (TRPC) channels are homologues of Drosophila TRP channel first cloned in mammalian cells. TRPC family consists of seven members which are nonselective cation channels with a high Ca2+ permeability and are activa
Externí odkaz:
https://doaj.org/article/9fb2f53ae29542388596613be57ce00d
Autor:
Enas Hussein Ali, Fatemeh Sharifpanah, Amer Taha, Suk Ying Tsang, Maria Wartenberg, Heinrich Sauer
Publikováno v:
Stem Cells International, Vol 2018 (2018)
The milk thistle (Silybum marianum (L.) Gaertn.) compound silibinin may be an inhibitor of the angiotensin II type 1 (AT1) receptor which is expressed in differentiating embryonic stem (ES) cells and is involved in the regulation of cardiomyogenesis.
Externí odkaz:
https://doaj.org/article/7abcb12dcd284bcaa7e55eab4c009b3c