Zobrazeno 1 - 10
of 717
pro vyhledávání: '"Suk Woo, Nam"'
Autor:
Sang Yean Kim, Min Jeong Na, Sungpil Yoon, Eunbi Shin, Jin Woong Ha, Soyoung Jeon, Suk Woo Nam
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 9, Pp 1909-1920 (2024)
Abstract Functional variations in coding and noncoding RNAs are crucial in tumorigenesis, with cancer-specific alterations often resulting from chemical modifications and posttranscriptional processes mediated by enzymes. These RNA variations have be
Externí odkaz:
https://doaj.org/article/431548a016714929969eff7f510251f3
Autor:
Jung Hwan Yoon, Jung Woo Eun, Hassan Ashktorab, Duane T. Smoot, Jeong kyu Kim, Suk Woo Nam, Won Sang Park
Publikováno v:
Oncogenesis, Vol 10, Iss 12, Pp 1-9 (2021)
Abstract Genomic stability maintenance requires correct DNA replication, chromosome segregation, and DNA repair, while defects of these processes result in tumor development or cell death. Although abnormalities in DNA replication and repair regulati
Externí odkaz:
https://doaj.org/article/d29bdd806bcd42e3a95e31148bcd67b4
Autor:
Soon Sun Kim, Geum Ok Baek, Ju A Son, Hye Ri Ahn, Moon Kyung Yoon, Hyo Jung Cho, Jung Hwan Yoon, Suk Woo Nam, Jae Youn Cheong, Jung Woo Eun
Publikováno v:
Molecular Oncology, Vol 15, Iss 10, Pp 2715-2731 (2021)
This study investigated the diagnostic potential of serum small extracellular vesicle‐derived long noncoding RNAs (EV‐lncRNAs) for hepatocellular carcinoma (HCC). Driver oncogenic lncRNA candidates were selected by a comparative analysis of lncRN
Externí odkaz:
https://doaj.org/article/0b449d3a7e7f44139e0ccb9ff36f2fbc
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-13 (2021)
Abstract Immune class in hepatocellular carcinoma (HCC) has been shown to possess immunogenic power; however, how preestablished immune landscapes in premalignant and early HCC stages impact the clinical outcomes of HCC patients remains unexplored. W
Externí odkaz:
https://doaj.org/article/be2d57dbb8d94979ae11c1777d38e809
Autor:
Soon Sun Kim, Geum Ok Baek, Hye Ri Ahn, Suna Sung, Chul Won Seo, Hyo Jung Cho, Suk Woo Nam, Jae Youn Cheong, Jung Woo Eun
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2646-2659 (2020)
This study aimed to identify novel long noncoding RNA (lncRNA) biomarkers for hepatocellular carcinoma (HCC) using publicly available tissue genomic datasets and validate their diagnostic utility for early‐stage HCC. Differentially expressed lncRNA
Externí odkaz:
https://doaj.org/article/7d14c1109eb84b118f6fd5d92648158a
Autor:
Hyo Jung Cho, Geum Ok Baek, Chul Won Seo, Hye Ri Ahn, Suna Sung, Ju A Son, Soon Sun Kim, Sung Won Cho, Jeong Won Jang, Suk Woo Nam, Jae Youn Cheong, Jung Woo Eun
Publikováno v:
Cancer Medicine, Vol 9, Iss 15, Pp 5459-5472 (2020)
Abstract Currently, a reliable serum biomarker for hepatocellular carcinoma (HCC) has not been established, particularly for early‐stage HCC (single tumor 0.8. In our validation study, serum exo‐miR‐4661‐5p could diagnose HCC in all stages (A
Externí odkaz:
https://doaj.org/article/7b960e86688147d0898fb0fe3467b534
Autor:
Hee Doo Yang, Suk Woo Nam
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 4, Pp 582-593 (2020)
Cancer: Mixed messages fuel tumor progression A single gene can generate a variety of RNA products, and changes in this final RNA output can directly contribute to cancer onset and progression. The initial transcription of each DNA sequence yields a
Externí odkaz:
https://doaj.org/article/4647165e0120430dac67885fccbb8550
Publikováno v:
Cancer Medicine, Vol 8, Iss 12, Pp 5507-5514 (2019)
Abstract Early detection of cancer provides effective treatment and saves lives. The objective of this study was to determine whether serum gastrokine 1 (GKN1) protein is a gastric cancer‐specific diagnostic biomarker. The serum concentration of GK
Externí odkaz:
https://doaj.org/article/cae9204c4b94431e88034ea72f721e28
Autor:
Hyung Seok Kim, Min Jeong Na, Keun Hong Son, Hee Doo Yang, Sang Yean Kim, Eunbi Shin, Jin Woong Ha, Soyoung Jeon, Keunsoo Kang, Kiho Moon, Won Sang Park, Suk Woo Nam
Publikováno v:
Experimental & Molecular Medicine. 55:95-107
Aberrant adenosine-to-inosine (A-to-I) RNA editing, catalyzed by adenosine deaminase acting on double-stranded RNA (ADAR), has been implicated in various cancers, but the mechanisms by which microRNA (miRNA) editing contributes to cancer development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7a42552d6a65f25475e68ab8333757
https://doi.org/10.1038/s12276-022-00916-8
https://doi.org/10.1038/s12276-022-00916-8
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract NKX6.3 plays an important role in gastric epithelial differentiation and also acts as a gastric tumor suppressor. The specific aim of this study was to determine whether NKX6.3 contributes to gastric mucosal barrier function by regulating re
Externí odkaz:
https://doaj.org/article/e70a1cf44a0b4f70b7143037e7728b7b