Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Suk W. Hong"'
PDF file - 102K, JSI-124 induces the mRNA expression of inflammatory genes in human xenograft GBM cells and murine primary astrocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7928d2c26be7455c0960c5b851d4d10
https://doi.org/10.1158/1541-7786.22510350
https://doi.org/10.1158/1541-7786.22510350
PDF file - 86K, JSI-124 induces the mRNA expression of inflammatory genes in human GBM cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae8dc95ce3871af2f63d598f4916521
https://doi.org/10.1158/1541-7786.22510353.v1
https://doi.org/10.1158/1541-7786.22510353.v1
PDF file - 82K, Effective inhibition of NF-κB using BAY-11 and shRNA knockdown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ada77502f34a793759e44ad06da0688
https://doi.org/10.1158/1541-7786.22510347
https://doi.org/10.1158/1541-7786.22510347
Data from Activation of the NF-κB Pathway by the STAT3 Inhibitor JSI-124 in Human Glioblastoma Cells
Glioblastoma tumors are characterized by their invasiveness and resistance to therapies. The transcription factor signal transducer and activator of transcription 3 (STAT3) was recently identified as a master transcriptional regulator in the mesenchy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b177ff2394727baa3d785532d6f6f03d
https://doi.org/10.1158/1541-7786.c.6539583
https://doi.org/10.1158/1541-7786.c.6539583
PDF file - 135K, JSI-124 inhibits stimulus-induced and constitutive JAK2/STAT3 phosphorylation and inhibits proliferation in GBM cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5fb29ed5a97c9363e1341320e3c1c3
https://doi.org/10.1158/1541-7786.22510356.v1
https://doi.org/10.1158/1541-7786.22510356.v1
PDF file - 75K, Inhibition of NF-κB does not prevent JSI-124 induced apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c6f21b8676de06fa2cc737f56115ae
https://doi.org/10.1158/1541-7786.22510344
https://doi.org/10.1158/1541-7786.22510344
Autor:
Braden C McFarland, Suk W Hong, Rajani Rajbhandari, George B Twitty, G Kenneth Gray, Hao Yu, Etty N Benveniste, Susan E Nozell
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78728 (2013)
Glioblastoma (GBM) is the most aggressive, neurologically destructive and deadly tumor of the central nervous system (CNS). In GBM, the transcription factors NF-κB and STAT3 are aberrantly activated and associated with tumor cell proliferation, surv
Externí odkaz:
https://doaj.org/article/b5fc7ee2c43f4af49ac189a525edcf27
Autor:
Sumaiya Sarwar, Mazin Al-Kasspooles, Anne D. Walling, Alexander E. Fondaw, Tyler Mouw, Peter J. DiPasco, Suk W. Hong
Publikováno v:
Journal of Surgical Research. 227:151-157
BACKGROUND It has been previously reported that over 20% of surgical trials will be discontinued prematurely raising ethical and financial concerns. Previous studies have been limited in scope owing to the need for manual review of selected trials. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014234de1b7b8289ec9fc27087c1eeb4
https://doi.org/10.1016/j.jss.2018.02.039
https://doi.org/10.1016/j.jss.2018.02.039
An NF-κB p65-cIAP2 link is necessary for mediating resistance to TNF-α induced cell death in gliomas
Autor:
George B. Twitty, Etty N. Benveniste, Xueyan Zhao, Marijke DeVos, Travis Laver, Suk W. Hong, Susan Nozell, Annelies DeVos
Publikováno v:
Journal of Neuro-Oncology. 102:367-381
Malignant gliomas are diffusively infiltrative and remain among the deadliest of all cancers. NF-κB is a transcription factor that mediates cell growth, migration and invasion, angiogenesis and resistance to apoptosis. Normally, the activity of NF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2125010554ce0806d966a2bf8eab7400
https://doi.org/10.1007/s11060-010-0346-y
https://doi.org/10.1007/s11060-010-0346-y