Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Suk Namgoong"'
Publikováno v:
PeerJ, Vol 6, p e5840 (2019)
Inhibition of both MEK1/2 and glycogen synthase kinase-3 (GSK3; 2i system) facilitates the maintenance of naïve stemness for embryonic stem cells in various mammalian species. However, the effect of the inhibition of the 2i system on porcine early e
Externí odkaz:
https://doaj.org/article/7ca13a95fed0412db51970eca6f92149
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120501 (2015)
The CRISPR/Cas9 system has proven to be an efficient gene-editing tool for genome modification of cells and organisms. However, the applicability and efficiency of this system in pig embryos have not been studied in depth. Here, we aimed to remove po
Externí odkaz:
https://doaj.org/article/10e88def543849ce928d2fe400ef3386
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123438 (2015)
Dynamic actin reorganization is the main driving force for spindle migration and asymmetric cell division in mammalian oocytes. It has been reported that various actin nucleators including Formin-2 are involved in the polarization of the spindle and
Externí odkaz:
https://doaj.org/article/0a33daf255b14b7990923ba6e8dbe258
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109385 (2014)
Junction-mediating and regulatory protein(JMY) is a multifunctional protein with roles in the transcriptional co-activation of p53 and the regulation of actin nucleation promoting factors and, hence, cell migration; however, its role in the maturatio
Externí odkaz:
https://doaj.org/article/8f9a8f79c4ca41b19eb119131c31a536
Autor:
Dongho Lee, Suk Namgoong, Jeongwoo Kwon, Yu-Jin Jo, Taeho Kwon, Zhe-Long Jin, Seung-Bin Yoon, Ji-Su Kim, Nam-Hyung Kim
Publikováno v:
Cell Cycle
WHAMM (WAS Protein Homolog Associated with Actin, Golgi Membranes, and Microtubules) is involved in Golgi membrane association, microtubule binding, and actin nucleation as a nucleation-promoting factor, which activates the actin-related protein 2/3
Autor:
Nam-Hyung Kim, Suk Namgoong
Publikováno v:
Biology of Reproduction. 98:153-161
In the final stage of oogenesis, mammalian oocytes generate a meiotic spindle and undergo chromosome segregation to yield an egg that is ready for fertilization. Herein, we describe the recent advances in understanding the mechanisms controlling form
Publikováno v:
The FASEB Journal. 32:625-638
Mammalian oocytes lack a centriole that acts as a microtubule organization center (MTOC) in most somatic cells. During oocyte maturation, MTOCs undergo remodeling processes, including decondensation, fragmentation, and self-organization. However, the
Publikováno v:
The FASEB Journal. 31:3677-3688
Dynamic changes in the actin network are crucial for the cortical migration of spindles and establishment of polarity, to ensure asymmetric division during meiotic maturation. In this study, filamin A (FLNA) was found to be an essential actin regulat
Autor:
Xiang-Shun Cui, Nam-Hyung Kim, Tian-Yi Sun, Suk Namgoong, Jeong Su Oh, HaiYang Wang, Yu-Jin Jo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863:2993-3000
To ensure accurate chromosome segregation, the spindle assembly checkpoint (SAC) delays anaphase onset by preventing the premature activation of anaphase-promoting complex/cyclosome (APC/C) until all kinetochores are attached to the spindle. Although
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNPA2/B1) plays an important role in RNA processing via in m6A modification of pre-mRNA or pre-miRNA. However, the functional role of and relationship between m6A and hnRNPA2/B1 in early embryonic deve