Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Suk Min Jang"'
Autor:
Dustin C. Becht, Brianna J. Klein, Akinori Kanai, Suk Min Jang, Khan L. Cox, Bing-Rui Zhou, Sabrina K. Phanor, Yi Zhang, Ruo-Wen Chen, Christopher C. Ebmeier, Catherine Lachance, Maxime Galloy, Amelie Fradet-Turcotte, Martha L. Bulyk, Yawen Bai, Michael G. Poirier, Jacques Côté, Akihiko Yokoyama, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Human acetyltransferases MOZ and MORF mediate development programs and are dysregulated in diseases. Here the authors identified two winged helix (WH) domains in MORF/MOZ and characterized their DNA binding functions, including targeting of CpG by WH
Externí odkaz:
https://doaj.org/article/a2ad2ef5ddc546e58f71dca700b8f668
Autor:
Mohamad Zandian, Suk Min Jang, Catherine Lachance, Arpan Acharya, Siddappa N. Byrareddy, Jacques Côté, Tatiana G. Kutateladze
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101853- (2022)
Summary: The SARS-CoV-2 envelope (E) protein hijacks human BRD4 (bromodomain and extra-terminal domain protein 4). Here, we describe a protocol to characterize the interaction of the acetylated E protein with BRD4 in vivo. We detail steps to use NMR
Externí odkaz:
https://doaj.org/article/9bf0e57f33c8441daf76c684d6c2f9de
Autor:
Brianna J. Klein, Khan L. Cox, Suk Min Jang, Rohit K. Singh, Jacques Côté, Michael G. Poirier, Tatiana G. Kutateladze
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100479- (2021)
Summary: The core subunit of the MORF acetyltransferase complex BRPF1 contains a unique combination of zinc fingers, including a plant homeodomain (PHD) finger followed by a zinc knuckle and another PHD finger, which together form a PZP domain (BRPF1
Externí odkaz:
https://doaj.org/article/a0fd143f19b94e7ea9ae4c1f09faf24e
Autor:
Brianna J. Klein, Suk Min Jang, Catherine Lachance, Wenyi Mi, Jie Lyu, Shun Sakuraba, Krzysztof Krajewski, Wesley W. Wang, Simone Sidoli, Jiuyang Liu, Yi Zhang, Xiaolu Wang, Becka M. Warfield, Andrew J. Kueh, Anne K. Voss, Tim Thomas, Benjamin A. Garcia, Wenshe R. Liu, Brian D. Strahl, Hidetoshi Kono, Wei Li, Xiaobing Shi, Jacques Côté, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Acetylation of histone H3K23 has emerged as an essential posttranslational modification, yet this epigenetic mark remains poorly understood. Here, the authors identify the native MORF complex as a histone H3K23-specific acetyltransferase and show tha
Externí odkaz:
https://doaj.org/article/78758c527c604e018605e9ed73ff1cd5
Autor:
Wanze Chen, Petra C. Schwalie, Eugenia V. Pankevich, Carine Gubelmann, Sunil K. Raghav, Riccardo Dainese, Marco Cassano, Michael Imbeault, Suk Min Jang, Julie Russeil, Tenagne Delessa, Julien Duc, Didier Trono, Christian Wolfrum, Bart Deplancke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Although Krüppel-associated box zinc finger proteins (KZFPs) were found to mostly repress transposable elements, recent studies found that KFZPs also play other roles in cells. Here, the authors provide evidence that the KZFP ZFP30 promotes adipogen
Externí odkaz:
https://doaj.org/article/79c0840feab948d880b74c9fb3a62bf1
Autor:
Benjamin Rauwel, Suk Min Jang, Marco Cassano, Adamandia Kapopoulou, Isabelle Barde, Didier Trono
Publikováno v:
eLife, Vol 4 (2015)
Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are normally controlled by the immune system, but can
Externí odkaz:
https://doaj.org/article/9c6d029a22c640eaa737dfe499233be6
Autor:
Anne Coléno-Costes, Suk Min Jang, Augustin de Vanssay, Julien Rougeot, Tahar Bouceba, Neel B Randsholt, Jean-Michel Gibert, Stéphane Le Crom, Emmanuèle Mouchel-Vielh, Sébastien Bloyer, Frédérique Peronnet
Publikováno v:
PLoS Genetics, Vol 8, Iss 10, p e1003006 (2012)
Chromodomains are found in many regulators of chromatin structure, and most of them recognize methylated lysines on histones. Here, we investigate the role of the Drosophila melanogaster protein Corto's chromodomain. The Enhancer of Trithorax and Pol
Externí odkaz:
https://doaj.org/article/d6c5bd326447471bbebd43f4c6e1b0e4
Autor:
Marc Lavigne, Ragnhild Eskeland, Saliha Azebi, Violaine Saint-André, Suk Min Jang, Eric Batsché, Hua-Ying Fan, Robert E Kingston, Axel Imhof, Christian Muchardt
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000769 (2009)
The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. These proteins contain two related domains known as the chromo- and the chromoshadow-domain. The chromo-domain binds histone H3 tails methylated on lysine
Externí odkaz:
https://doaj.org/article/7b7d538d14c34f8483cc97b765d7c9dd
Autor:
Kendra R. Vann, Arpan Acharya, Suk Min Jang, Catherine Lachance, Mohamad Zandian, Tina A. Holt, Audrey L. Smith, Kabita Pandey, Donald L. Durden, Dalia El-Gamal, Jacques Côté, Siddappa N. Byrareddy, Tatiana G. Kutateladze
Publikováno v:
Structure (London, England : 1993). 30(9)
Emerging new variants of SARS-CoV-2 and inevitable acquired drug resistance call for the continued search of new pharmacological targets to fight the potentially fatal infection. Here, we describe the mechanisms by which the E protein of SARS-CoV-2 h
Autor:
Jacques Côté, Tatiana G. Kutateladze, Khan L. Cox, Suk Min Jang, Rohit Singh, Michael G. Poirier, Brianna J. Klein
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 2, Pp 100479-(2021)
STAR Protocols, Vol 2, Iss 2, Pp 100479-(2021)
Summary The core subunit of the MORF acetyltransferase complex BRPF1 contains a unique combination of zinc fingers, including a plant homeodomain (PHD) finger followed by a zinc knuckle and another PHD finger, which together form a PZP domain (BRPF1P