The tryptophan metabolic pathway of the microbiome and host cells in health and disease.

Autor: Miyamoto K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.; Miyarisan Pharmaceutical Co., Research Laboratory, Tokyo, Japan., Sujino T; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.; Keio Global Research Institute, Keio University, Tokyo, Japan., Kanai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Publikováno v: International immunology [Int Immunol] 2024 Nov 14; Vol. 36 (12), pp. 601-616.

Feasibility of endoscopic submucosal dissection including papilla (with video).

Autor: Yahagi N; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Takatori Y; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Sasaki M; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Imura Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Murata S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Sato T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Minezaki D; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Hayakawa T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Nakajima Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Okada H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Sakurai H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Tojo A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Iwata K; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Miyazaki K; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Kayashima A; Department of Gastroenterology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan., Masunaga T; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Mizutani M; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Akimoto T; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Seino T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kawasaki S; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Horibe M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Fukuhara S; Department of Gastroenterology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan., Matsuura N; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Sujino T; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Nakayama A; Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan., Takabayashi K; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Iwasaki E; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kato M; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.

Publikováno v: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society [Dig Endosc] 2024 Nov 03. Date of Electronic Publication: 2024 Nov 03.

Ulcerative colitis-associated neoplasms often harbor poor prognostic histologic components with low detection by biopsy.

Autor: Sakakibara R; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Sugimoto S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Takabayashi K; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Kiyohara H; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Wakisaka Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kaieda Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kawaida M; Department of Pathology, Keio University School of Medicine, Tokyo, Japan., Yoshimatsu Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Sujino T; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Hosoe N; Center for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan., Kato M; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Shimoda M; Department of Pathology, Keio University School of Medicine, Tokyo, Japan., Mikami Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Iwao Y; Center for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan., Kanai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Publikováno v: Intestinal research [Intest Res] 2024 Oct; Vol. 22 (4), pp. 428-438. Date of Electronic Publication: 2024 May 07.

Distinctive duodenal microbiomes and bile acid profiles in duodenal tumor patients revealed by prospective observational study.

Autor: Kubosawa Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Sujino T; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. tsujino1224@keio.jp.; Keio Global Research Institute, Keio Univerisy, Mita, Tokyo, 108-0073, Japan. tsujino1224@keio.jp.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. tsujino1224@keio.jp., Miyamoto K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Central Research Institute, Miyarisan Pharmaceutical Co., Ltd., 2-22-9, Torocho, Kita-ku, Saitama-shi, Saitama, 331-0804, Japan., Kayashima A; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Minezaki D; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Morioka K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Iwata K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Miyazaki K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Masunaga T; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Mizutani M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Akimoto T; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Takatori Y; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Matsuura N; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Nakayama A; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Takabayashi K; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Nakamoto N; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Honda A; Division of Gastroenterology and Hepatology, Tokyo Medical University Ibaraki Medical Center, 3-20-1 chuo, Ami-machi, Inashiki-gun, Ibaraki, 300-0395, Japan., Kato M; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Yahagi N; Division of Research and Development for Minimally Invasive Treatment Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan., Kanai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. takagast@keio.jp.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. takagast@keio.jp.

Publikováno v: Scientific reports [Sci Rep] 2024 Aug 12; Vol. 14 (1), pp. 18705. Date of Electronic Publication: 2024 Aug 12.

Downregulation of chemokine receptor 9 facilitates CD4 ⁺ CD8αα ⁺ intraepithelial lymphocyte development.

Autor: Ono K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Sujino T; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan. tsujino1224@keio.jp., Miyamoto K; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.; Research Laboratory, Miyarisan Pharmaceutical Co., Tokyo, Japan., Harada Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kojo S; Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Division of Immunology and Stem Cell Biology, Institute of Medical, Pharmaceutical and Health Science, Kanazawa University, Kanazawa, Japan., Yoshimatsu Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Tanemoto S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Koda Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.; Mitsubishi Tanabe Pharma Corporation, Kanagawa, Japan., Zheng J; Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Sayama K; Applied Life Science Course, College of Agriculture, Shizuoka University, Shizuoka, Japan., Koide T; Mouse Genomics Resource Laboratory, National Institute of Genetics, Shizuoka, Japan., Teratani T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Mikami Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Takabayashi K; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Nakamoto N; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Hosoe N; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., London M; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, 10065, USA., Ogata H; Center for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan., Mucida D; Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, 10065, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, 10065, USA., Taniuchi I; Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kanai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan. takagast@keio.jp.

Publikováno v: Nature communications [Nat Commun] 2023 Aug 24; Vol. 14 (1), pp. 5152. Date of Electronic Publication: 2023 Aug 24.