Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sujeenthar Tharmalingam"'
Autor:
Alexandra Jameus, Jessica Dougherty, Ramya Narendrula, Daniela Levert, Manon Valiquette, Jake Pirkkanen, Christine Lalonde, Patrice Bonin, Jeffrey D. Gagnon, Vasu D. Appanna, Sujeenthar Tharmalingam, Christopher Thome
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3339 (2024)
Radiation therapy for abdominopelvic malignancies often results in damage to the gastrointestinal tract (GIT) and permanent changes in bowel function. An overlooked component of the pathophysiology of radiation-induced bowel injury is the role of the
Externí odkaz:
https://doaj.org/article/c137a9bd1f084e2a981fe41f50bb493b
Autor:
Simon Paquette, Sean C. Thomas, Krishnan Venkataraman, Vasu D. Appanna, Sujeenthar Tharmalingam
Publikováno v:
Nutrients, Vol 15, Iss 21, p 4690 (2023)
Type 2 diabetes mellitus (T2DM) remains a global health concern. Emerging clinical trial (CT) evidence suggests that probiotic intervention may promote a healthy gut microbiome in individuals with T2DM, thereby improving management of the disease. Th
Externí odkaz:
https://doaj.org/article/efdf2196af9e403c84fcaa960c31b541
Autor:
Karolina M. Czajka, Krishnan Venkataraman, Danielle Brabant-Kirwan, Stacey A. Santi, Chris Verschoor, Vasu D. Appanna, Ravi Singh, Deborah P. Saunders, Sujeenthar Tharmalingam
Publikováno v:
Cells, Vol 12, Iss 22, p 2655 (2023)
Candidiasis is a highly pervasive infection posing major health risks, especially for immunocompromised populations. Pathogenic Candida species have evolved intrinsic and acquired resistance to a variety of antifungal medications. The primary goal of
Externí odkaz:
https://doaj.org/article/52a8513d905e414c8b53a35b79c488fe
Autor:
Wuroud Al-khayyat, Jake Pirkkanen, Jessica Dougherty, Taylor Laframboise, Noah Dickinson, Neelam Khaper, Simon J. Lees, Marc S. Mendonca, Douglas R. Boreham, Tze Chun Tai, Christopher Thome, Sujeenthar Tharmalingam
Publikováno v:
Cells, Vol 12, Iss 19, p 2344 (2023)
FRA1 (FOSL1) is a transcription factor and a member of the activator protein-1 superfamily. FRA1 is expressed in most tissues at low levels, and its expression is robustly induced in response to extracellular signals, leading to downstream cellular p
Externí odkaz:
https://doaj.org/article/97e78abc7b564ab78a3bf94c76304faa
Publikováno v:
Microbiology Research, Vol 13, Iss 2, Pp 219-234 (2022)
HIV and AIDS patients are susceptible to opportunistic infections. Oral candidiasis or thrush is the primary manifestation of fungal infection in these patients. The primary objective of this literature review was to summarize established and novel t
Externí odkaz:
https://doaj.org/article/da11c25c05934fd399f01e94e161ce1a
Autor:
Ian S. Dayes, MD, Allison E. Kennedy, PhD, Sameer Parpia, PhD, Christopher Thome, PhD, Sujeenthar Tharmalingam, PhD, Jennifer A. Lemon, PhD, Dawn M.E. Bowdish, PhD, Douglas R. Boreham, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 1, Pp 101066- (2023)
Purpose: Nontargeted low-dose ionizing radiation has been proposed as a cancer therapeutic for several decades; however, questions remain about the duration of hematological changes and optimal dosing regimen. Early studies delivering fractionated lo
Externí odkaz:
https://doaj.org/article/7574cee7544042349ed54576e8702900
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Prenatal stress through glucocorticoid (GC) exposure leads to an increased risk of developing diseases such as cardiovascular disease, metabolic syndrome and hypertension in adulthood. We have previously shown that administration of the synt
Externí odkaz:
https://doaj.org/article/0c47c808289f4087a06a990c7099d406
Autor:
Christine Lalonde, Shayenthiran Sreetharan, Alyssa Murray, Lisa Stoa, Mary Ellen Cybulski, Allison Kennedy, Nicholas Landry, Amy Stillar, Sandhya Khurana, Sujeenthar Tharmalingam, Joanna Wilson, Neelam Khaper, Simon J. Lees, Douglas Boreham, T. C. Tai
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8466 (2023)
The exposure of ionizing radiation during early gestation often leads to deleterious and even lethal effects; however, few extensive studies have been conducted on late gestational exposures. This research examined the behavior al effects of C57Bl/6J
Externí odkaz:
https://doaj.org/article/eaf24def52d14937a04f4f643172e127
Autor:
Christine Lalonde, Julie Grandbois, Sandhya Khurana, Alyssa Murray, Sujeenthar Tharmalingam, T. C. Tai
Publikováno v:
Brain and Behavior, Vol 11, Iss 4, Pp n/a-n/a (2021)
Abstract Introduction Fetal programming was characterized a few decades ago, explaining the correlation of physiological phenotypes of offspring exposed to early‐life stress. High acute or chronic prenatal stress can overwhelm the enzymatic placent
Externí odkaz:
https://doaj.org/article/e0686224563e4b10a6dcd487f87b0baa
Autor:
Alyssa Murray, Sujeenthar Tharmalingam, Sandhya Khurana, Christine Lalonde, Phong Nguyen, T. C. Tai
Publikováno v:
Cells, Vol 11, Iss 10, p 1613 (2022)
Circadian clocks control many vital aspects of physiology from the sleep-wake cycle to metabolism. The circadian clock operates through transcriptional-translational feedback loops. The normal circadian signaling relies on a ‘master clock’, locat
Externí odkaz:
https://doaj.org/article/55fa67a57ee94b2a9b86b5fa277749b8