Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sujatha Chilakala"'
Autor:
Reem Abdel-Haq, Johannes CM Schlachetzki, Joseph C Boktor, Thaisa M Cantu-Jungles, Taren Thron, Mengying Zhang, John W Bostick, Tahmineh Khazaei, Sujatha Chilakala, Livia H Morais, Greg Humphrey, Ali Keshavarzian, Jonathan E Katz, Matthew Thomson, Rob Knight, Viviana Gradinaru, Bruce R Hamaker, Christopher K Glass, Sarkis K Mazmanian
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/ae613a4d8f094aabb779d6656ef3d63d
Autor:
Reem Abdel-Haq, Johannes CM Schlachetzki, Joseph C Boktor, Thaisa M Cantu-Jungles, Taren Thron, Mengying Zhang, John W Bostick, Tahmineh Khazaei, Sujatha Chilakala, Livia H Morais, Greg Humphrey, Ali Keshavarzian, Jonathan E Katz, Matthew Thomson, Rob Knight, Viviana Gradinaru, Bruce R Hamaker, Christopher K Glass, Sarkis K Mazmanian
Publikováno v:
eLife, Vol 11 (2022)
Parkinson’s disease (PD) is a movement disorder characterized by neuroinflammation, α-synuclein pathology, and neurodegeneration. Most cases of PD are non-hereditary, suggesting a strong role for environmental factors, and it has been speculated t
Externí odkaz:
https://doaj.org/article/3e8300bf84174f8ebedaa019922d4062
Autor:
Carly Strelez, Sujatha Chilakala, Kimya Ghaffarian, Roy Lau, Erin Spiller, Nolan Ung, Danielle Hixon, Ah Young Yoon, Ren X. Sun, Heinz-Josef Lenz, Jonathan E. Katz, Shannon M. Mumenthaler
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102509- (2021)
Summary: Colorectal cancer (CRC) progression is a complex process that is not well understood. We describe an in vitro organ-on-chip model that emulates in vivo tissue structure and the tumor microenvironment (TME) to better understand intravasation,
Externí odkaz:
https://doaj.org/article/caf16ab096014c8ea201b27cc1beccf1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2017)
Lon, also known as Protease La, is one of the simplest ATP-dependent proteases. It is a homooligomeric enzyme comprised of an ATPase domain and a proteolytic domain in each enzyme subunit. Despite sharing about 40% sequence identity, human and Escher
Externí odkaz:
https://doaj.org/article/89dba82064764e43a7f699f03316d44f
Autor:
Frederic J. Reu, Samantha Tall, Rebecca R. Kuang, Sujatha Chilakala, Yan Xu, Claudiu Cotta, Mitchell R. Smith, Clark W. Distelhorst, Fei Zhong, Daniel J. Lindner, Yvonne Parker, Dale Grabowski, Jennifer Hu, Shravya Govindgari, Babal K. Jha, James G. Phillips, Sergei Vatolin
Mass spectrometric analysis of proteins that bound to B-CCF642 in MM1.S cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c863bfec9e13b2344c01c8be79219f
https://doi.org/10.1158/0008-5472.22410824.v1
https://doi.org/10.1158/0008-5472.22410824.v1
Autor:
Frederic J. Reu, Samantha Tall, Rebecca R. Kuang, Sujatha Chilakala, Yan Xu, Claudiu Cotta, Mitchell R. Smith, Clark W. Distelhorst, Fei Zhong, Daniel J. Lindner, Yvonne Parker, Dale Grabowski, Jennifer Hu, Shravya Govindgari, Babal K. Jha, James G. Phillips, Sergei Vatolin
S2: Inactivation of bortezomib by liver homogenate; S3: CCF642 effect on survival of normal bone marrow, myeloid neoplasia, myeloma and lymphoma cells; S4: Biotin-stained Western blot after treatment of MM1.S cells with B-CCF642
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce403ede8fe1e0420fc80bdfdeb3cd7
https://doi.org/10.1158/0008-5472.22410833.v1
https://doi.org/10.1158/0008-5472.22410833.v1
Autor:
Frederic J. Reu, Samantha Tall, Rebecca R. Kuang, Sujatha Chilakala, Yan Xu, Claudiu Cotta, Mitchell R. Smith, Clark W. Distelhorst, Fei Zhong, Daniel J. Lindner, Yvonne Parker, Dale Grabowski, Jennifer Hu, Shravya Govindgari, Babal K. Jha, James G. Phillips, Sergei Vatolin
Reagent and chemical library screening details, liver homogenate preparation, CCF642 animal treatment formulation, chemical synthesis schemes, details of proteomic analysis, PDI activity assay and PDI mutant primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fb8da3f89bf8e876d5d56744e31eac
https://doi.org/10.1158/0008-5472.22410830.v1
https://doi.org/10.1158/0008-5472.22410830.v1
Autor:
Frederic J. Reu, Samantha Tall, Rebecca R. Kuang, Sujatha Chilakala, Yan Xu, Claudiu Cotta, Mitchell R. Smith, Clark W. Distelhorst, Fei Zhong, Daniel J. Lindner, Yvonne Parker, Dale Grabowski, Jennifer Hu, Shravya Govindgari, Babal K. Jha, James G. Phillips, Sergei Vatolin
Legends to Supplementary Figures S1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a233e79bcf1ce1e3a1a9febd03bb829
https://doi.org/10.1158/0008-5472.22410839.v1
https://doi.org/10.1158/0008-5472.22410839.v1
Autor:
Frederic J. Reu, Samantha Tall, Rebecca R. Kuang, Sujatha Chilakala, Yan Xu, Claudiu Cotta, Mitchell R. Smith, Clark W. Distelhorst, Fei Zhong, Daniel J. Lindner, Yvonne Parker, Dale Grabowski, Jennifer Hu, Shravya Govindgari, Babal K. Jha, James G. Phillips, Sergei Vatolin
Multiple myeloma cells secrete more disulfide bond–rich proteins than any other mammalian cell. Thus, inhibition of protein disulfide isomerases (PDI) required for protein folding in the endoplasmic reticulum (ER) should increase ER stress beyond r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4f1af1a6bdbf73f1a68c254cbd67c5
https://doi.org/10.1158/0008-5472.c.6508079
https://doi.org/10.1158/0008-5472.c.6508079
Autor:
Frederic J. Reu, Samantha Tall, Rebecca R. Kuang, Sujatha Chilakala, Yan Xu, Claudiu Cotta, Mitchell R. Smith, Clark W. Distelhorst, Fei Zhong, Daniel J. Lindner, Yvonne Parker, Dale Grabowski, Jennifer Hu, Shravya Govindgari, Babal K. Jha, James G. Phillips, Sergei Vatolin
Structure, H-NMR and HRMS of CCF642, B-CCF642 and CCF642-COOH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4277383070d38da2a1ed8e084c99120c
https://doi.org/10.1158/0008-5472.22410836
https://doi.org/10.1158/0008-5472.22410836