Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sujata Vijh"'
Autor:
Sujata Vijh, Carol E. Wang, Nelson L. Michael, Zakaria Imam, Debora E. Dayhoff, Philip K. Ehrenberg
Publikováno v:
Genomics. 80:86-95
The chemokine receptor CCR3 has a critical function in the pathogenesis of eosinophilic diseases and is an entry co-receptor for HIV-1. We describe here the genomic organization and general transcriptional control mechanism for the human gene CCR3. W
Autor:
Roman A. Tuma, Sujata Vijh, Grégoire Lauvau, Eric G. Pamer, Natalya V. Serbina, Tiffany Horng, Kristen M. Kerksiek, Philip Kong
Publikováno v:
Science. 294:1735-1739
Killed or inactivated vaccines targeting intracellular bacterial and protozoal pathogens are notoriously ineffective at generating protective immunity. For example, vaccination with heat-killedListeria monocytogenes(HKLM) is not protective, although
Autor:
Eric G. Pamer, Roberto Mercado, Sujata Vijh, Kristen M. Kerksiek, Ingrid M. Pilip, S. Elise Allen
Publikováno v:
The Journal of Immunology. 165:6833-6839
The duration of infection and the quantity of Ag presented in vivo are commonly assumed to influence, if not determine, the magnitude of T cell responses. Although the cessation of in vivo T cell expansion coincides with bacterial clearance in mice i
Publikováno v:
Infection and Immunity. 67:1303-1309
Listeria monocytogenes is an intracellular bacterium that elicits complex cytotoxic T-lymphocyte (CTL) responses in infected mice. The responses of CTL populations that differ in antigen specificity range in magnitude from large, dominant responses t
Publikováno v:
The Journal of Immunology. 160:3971-3977
T lymphocytes eradicate and provide long-term immunity to infections caused by intracellular pathogens. The mechanisms that determine in vivo T cell response sizes are poorly understood. Although it is speculated that the relative processing efficien
Publikováno v:
Immunity. 8:353-362
Bacterial infections activate complex T cell populations that differ in size and antigen specificity. We used tetramerized MHC class I molecules complexed with Listeria monocytogenes–derived epitopes to characterize four distinct CD8+ T lymphocyte
Publikováno v:
Journal of Virology. 70:4466-4473
Synergistic neutralization of human immunodeficiency virus type 1 (HIV-1) was observed in studies using a chimpanzee anti-V2 monoclonal antibody (MAb), C108G, in combination with anti-V3 loop and anti-CD4 binding-site (bs) MAbs of different epitope s
Publikováno v:
Molecular Immunology. 32:1081-1092
The variable (V) regions of C108G, a potent neutralizing chimpanzee mAb against a glycan-dependent epitope in the V2 region of HIV-1 gp120, have been characterized for reactivity with human VH and VK family-specific antisera, and their nucleotide seq
Autor:
Jeffrey B, Stavenhagen, Sergey, Gorlatov, Nadine, Tuaillon, Christopher T, Rankin, Hua, Li, Stephen, Burke, Ling, Huang, Sujata, Vijh, Syd, Johnson, Ezio, Bonvini, Scott, Koenig
Publikováno v:
Cancer research. 67(18)
Monoclonal antibodies (mAb) are widely used in the treatment of non-Hodgkin's lymphoma and autoimmune diseases. Although the mechanism of action in vivo is not always known, the therapeutic activity of several approved mAbs depends on the binding of
Publikováno v:
Immunological reviews. 158
Summary: Listeria monocytogenes (L. monocytogenes) secretes proteins associated with its virulence into the cytosol of infected cells. These secreted proteins are degraded by host cell proteasomes and processed into peptides that are bound by MHC cla