Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sujata, Chakraborty"'
Publikováno v:
Indian Heart Journal, Vol 67, Iss S1, p S59 (2015)
Externí odkaz:
https://doaj.org/article/f24aec27e3a54f9699b1623a62b0afcc
Autor:
Sujata Chakraborty, Ethan Ahler, Jessica J. Simon, Linglan Fang, Zachary E. Potter, Katherine A. Sitko, Jason J. Stephany, Miklos Guttman, Douglas M. Fowler, Dustin J. Maly
SUMMARYKinase inhibitors are effective cancer therapies but resistance often limits clinical efficacy. Despite the cataloguing of numerous resistance mutations, our understanding of kinase inhibitor resistance is still incomplete. Here, we comprehens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7ae707de4e31560372338c6caa63e24
https://doi.org/10.1101/2021.12.05.471322
https://doi.org/10.1101/2021.12.05.471322
Autor:
Zachary E. Potter, Linglan Fang, Emily M. Dieter, Dustin J. Maly, Chloe K. Lombard, Sujata Chakraborty
Publikováno v:
J Am Chem Soc
Small molecule inhibitors often only block a subset of the cellular functions of their protein targets. In many cases, how inhibiting only a portion of a multi-functional protein’s functions affects the state of the cell is not well understood. The
Autor:
Markus A. Seeliger, Ames C. Register, Sujata Chakraborty, Zachary E. Potter, Linglan Fang, Dustin J. Maly, Jessica Vilas-Boas
Publikováno v:
ACS Chem Biol
Small molecule kinase inhibitors that stabilize distinct ATP binding site conformations can differentially modulate the global conformation of Src-family kinases (SFKs). However, it is unclear which specific ATP binding site contacts are responsible
Publikováno v:
ACS Chem Biol
ATP-competitive inhibitors that demonstrate exquisite selectivity for specific members of the human kinome have been developed. Despite this success, the identification of highly selective inhibitors is still very challenging, and it is often not pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0a6015277b10362a0b382c4006d499
https://europepmc.org/articles/PMC6642640/
https://europepmc.org/articles/PMC6642640/
Autor:
Zachary E. Potter, Sujata Chakraborty, Linglan Fang, Dustin J. Maly, Ho-Tak Lau, Douglas M. Fowler, Miklos Guttman, Shao En Ong
Publikováno v:
Cell Chem Biol
Solution-based structural techniques complement high-resolution structural data by providing insight into the oft-missed links between protein structure and dynamics. Here, we present Parallel Chemoselective Profiling, a solution-based structural met
Autor:
Sujata Chakraborty, Nabin Baran Manik
Publikováno v:
Frontiers of Optoelectronics. 8:289-297
In this work, we investigated the effect of single walled carbon nanotubes (SWCNT) on the electrical and photovoltaic properties of methyl red (MR) dye based photoelectrochemical cell (PEC). MR dye based PEC with LiClO4 as ion salt were fabricated wi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1636
The Src family kinases (SFKs) are an important family of tyrosine kinases that are allosterically regulated by their SH2 and SH3 domains. Engagement of SFK SH2 and SH3 domains with their intramolecular ligands leads to reduced kinase activity by stab
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971527
The Src family kinases (SFKs) are an important family of tyrosine kinases that are allosterically regulated by their SH2 and SH3 domains. Engagement of SFK SH2 and SH3 domains with their intramolecular ligands leads to reduced kinase activity by stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9d6c59b90f09259a7f47011f0e7663
https://doi.org/10.1007/978-1-4939-7154-1_6
https://doi.org/10.1007/978-1-4939-7154-1_6
Autor:
Holli M. Drendel, Jill L. Reiter, Megan M. Schellinger, Gil Mor, Sujata Chakraborty, Men-Jean Lee
Publikováno v:
Placenta. 52
Immortalization of primary cells with telomerase is thought to maintain normal phenotypic properties and avoid chromosomal abnormalities and other cancer-associated changes that occur following simian virus 40 tumor antigen (SV40 Tag) induced immorta