Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Suhong Pang"'
Publikováno v:
Journal of Modern Power Systems and Clean Energy, Vol 6, Iss 1, Pp 27-39 (2018)
Along with the improvement of electrical equipment reliability, people's unsafe behaviors and human errors have become one of main sources of risks in power systems. However, there is no comprehensive study on human factors and human reliability anal
Externí odkaz:
https://doaj.org/article/af06b6cc91a746168a2901dddeef4c54
Publikováno v:
Sustainable Cities and Society. 76:103418
Using blockchain technology (BCT) in securing data has received a lot of attention these days. This technology is used not only as a new way with the aim of enhancing the cyber and physical security of power systems, but also has been applied to enha
Publikováno v:
2015 IEEE PES Asia-Pacific Power and Energy Engineering Conference (APPEEC).
With the development of power industry, the scale of power system is much larger and power system operations are becoming increasingly complicated and critical. In allusion to this situation, power system specific training for power system dispatcher
Autor:
Donna L. Pedicord, Sujatha Nagulapalli, Caroline Fanslau, Lata Jayaraman, Jonathan Lippy, Hillary Gray, Suhong Pang, Yuval Blat
Publikováno v:
Analytical Biochemistry. 402:65-68
Histone acetyl transferases are important regulators of cellular homeostasis. This study describes a sensitive acetyl transferase electrophoretic mobility shift assay applicable both for kinetic analysis of acetyl transferase inhibitors and for high-
Autor:
Matthew V. Lorenzi, Wayne Vaccaro, Marco M. Gottardis, Simona Bindi, Michael A. Poss, Sandrine Thieffine, George L. Trainor, Lata Jayaraman, Paola Vianello, Fulvia Roletto, Ashok V. Purandare, Suhong Pang, Zhong Chen, Tram N. Huynh, Arturo Galvani, Jieping Geng, Tiziano Bandiera
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:2924-2927
Design, synthesis, and SAR development led to the identification of the potent, novel, and selective pyrazole based inhibitor (7f) of Coactivator Associated Arginine Methyltransferase (CARM1).
Autor:
Suhong Pang, Michael A. Poss, Zhong Chen, Ashok V. Purandare, Kimberly Nowak, Wayne Vaccaro, Tram N. Huynh, Jieping Geng, Lata Jayaraman, Jonathan O’Connell
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4438-4441
This study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.
Autor:
Bang-Chi Chen, Suhong Pang, Steven H. Spergel, Leslie Leith, David J. Shuster, John Wityak, Derek J. Norris, Jagabandhu Das, Rulin Zhao, Gary L. Schieven, Kim W. McIntyre, Joel C. Barrish, Rosemary Zhang, Kamelia Behnia, Ding Ren Shen, Sidney Pitt, Arthur M. Doweyko, Ping Chen, Henry F. De Fex
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:6061-6066
A series of substituted 2-(aminoheteroaryl)-thiazole-5-carboxamide analogs have been synthesized as novel, potent inhibitors of the Src-family kinase p56Lck. Among them, compound 2 displayed superior in vitro potency and excellent in vivo efficacy.
Autor:
John Wityak, Amrita Kamath, Louis J. Lombardo, Ping Chen, John T. Hunt, Ivan Inigo, Stephen Castaneda, Joel C. Barrish, Herbert E. Klei, Robert J. Schmidt, John S. Tokarski, Sidney Pitt, Derek J. Norris, Francis Y. Lee, Jagabandhu Das, Craig Fairchild, Kathy A. Johnston, Punit Marathe, Robert M. Borzilleri, Cornelius Lyndon A M, Suhong Pang, Mei-Li Wen, Russell Peterson, Gary L. Schieven, Kamelia Behnia, David Kan, Arthur M. Doweyko
Publikováno v:
Journal of Medicinal Chemistry. 47:6658-6661
A series of substituted 2-(aminopyridyl)- and 2-(aminopyrimidinyl)thiazole-5-carboxamides was identified as potent Src/Abl kinase inhibitors with excellent antiproliferative activity against hematological and solid tumor cell lines. Compound 13 was o
Autor:
Steven H. Spergel, Robert V. Moquin, Ding Ren Shen, Jagabundhu Das, Gary L. Schieven, Kamelia Behnia, James Lin, O. Kocy, Paul L. Stanley, Sydney Pitt, John Wityak, Ping Chen, Sara Thrall, David J. Shuster, Derek J. Norris, Suhong Pang, Edwin J. Iwanowicz, Steven B. Kanner, Henry F. De Fex, Joel C. Barrish, Henry H. Gu, Kim W. McIntyre, Mark R. Witmer, Saeho Chong, Arthur M. Doweyko
Publikováno v:
Journal of Medicinal Chemistry. 47:4517-4529
A series of novel anilino 5-azaimidazoquinoxaline analogues possessing potent in vitro activity against p56Lck and T cell proliferation have been discovered. Subsequent SAR studies led to the identification of compound 4 (BMS-279700) as an orally act
Autor:
Jagabandhu Das, Sidney Pitt, Gary L. Schieven, Ding Ren Shen, Robert V. Moquin, Henry F. DeFex, James Lin, John Wityak, Qiong Fang, Suhong Pang, Zhongqi Shen, Joel C. Barrish, Steven H. Spergel, Arthur M. Doweyko
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:2145-2149
A series of structurally novel benzothiazole based small molecule inhibitors of p56(lck) were prepared to elucidate their structure-activity relationships (SARs), selectivity and cell activity in the T-cell proliferation assay. BMS-243117 (compound 2