Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Suho, Lee"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The human genome is highly dynamic across all scales. At the gene level, chromatin is persistently remodeled and rearranged during active processes such as transcription, replication and DNA repair. At the genome level, chromatin moves in mi
Externí odkaz:
https://doaj.org/article/6da896501e2640dd86bbb80fec1a6dd5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Extracellular vesicle-derived DNA (evDNA) encapsulates the complete genome and mutational status of cells; however, whether cancer cell-derived evDNA mirrors the epigenetic features of parental genomic DNA remains uncertain. This study aimed
Externí odkaz:
https://doaj.org/article/c921d938043246669266f4aebcd121ee
Autor:
Seongryong Kim, Galam Leem, Junjeong Choi, Yongjun Koh, Suho Lee, Sang-Hee Nam, Jin Su Kim, Chan Hee Park, Ho Kyoung Hwang, Kyoung Il Min, Jung Hyun Jo, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Eui-Cheol Shin, Chang Moo Kang, Seungmin Bang, Jong-Eun Park
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Recent studies using single-cell transcriptomic analysis have reported several distinct clusters of neoplastic epithelial cells and cancer-associated fibroblasts in the pancreatic cancer tumor microenvironment. However, their mole
Externí odkaz:
https://doaj.org/article/1c44fc99a70f419f9ea61b463f3a7c7e
Autor:
Mihyun Bae, Junyeop Daniel Roh, Youjoung Kim, Seong Soon Kim, Hye Min Han, Esther Yang, Hyojin Kang, Suho Lee, Jin Yong Kim, Ryeonghwa Kang, Hwajin Jung, Taesun Yoo, Hyosang Kim, Doyoun Kim, Heejeong Oh, Sungwook Han, Dayeon Kim, Jinju Han, Yong Chul Bae, Hyun Kim, Sunjoo Ahn, Andrew M Chan, Daeyoup Lee, Jin Woo Kim, Eunjoon Kim
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2653-2653 (2024)
Externí odkaz:
https://doaj.org/article/2d03b1ed267d47f38fffedfba864727a
Autor:
Ryeonghwa Kang, Kyungdeok Kim, Yewon Jung, Sang-Han Choi, Chanhee Lee, Geun Ho Im, Miram Shin, Kwangmin Ryu, Subin Choi, Esther Yang, Wangyong Shin, Seungjoon Lee, Suho Lee, Zachary Papadopoulos, Ji Hoon Ahn, Gou Young Koh, Jonathan Kipnis, Hyojin Kang, Hyun Kim, Won-Ki Cho, Soochul Park, Seong-Gi Kim, Eunjoon Kim
Publikováno v:
PLoS Biology, Vol 22, Iss 5, p e3002596 (2024)
Autism spectrum disorders (ASD) frequently accompany macrocephaly, which often involves hydrocephalic enlargement of brain ventricles. Katnal2 is a microtubule-regulatory protein strongly linked to ASD, but it remains unclear whether Katnal2 knockout
Externí odkaz:
https://doaj.org/article/5c97fd7bf8714d0980f93431d5b5bc26
Autor:
Hyoseon Oh, Suho Lee, Yusang Oh, Seongbin Kim, Young Seo Kim, Yeji Yang, Woochul Choi, Ye-Eun Yoo, Heejin Cho, Seungjoon Lee, Esther Yang, Wuhyun Koh, Woojin Won, Ryunhee Kim, C. Justin Lee, Hyun Kim, Hyojin Kang, Jin Young Kim, Taeyun Ku, Se-Bum Paik, Eunjoon Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Autism spectrum disorders (ASD) represent neurodevelopmental disorders characterized by social deficits, repetitive behaviors, and various comorbidities, including epilepsy. ANK2, which encodes a neuronal scaffolding protein, is frequently m
Externí odkaz:
https://doaj.org/article/787422ac29024af5a2e220ea54e9cc29
Autor:
A. Harrison Brody, Sarah Helena Nies, Fulin Guan, Levi M. Smith, Bandhan Mukherjee, Santiago A. Salazar, Suho Lee, Tu Kiet T. Lam, Stephen M. Strittmatter
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-33 (2022)
Abstract Background Genetic variation at the PTK2B locus encoding the protein Pyk2 influences Alzheimer’s disease risk. Neurons express Pyk2 and the protein is required for Amyloid-β (Aβ) peptide driven deficits of synaptic function and memory in
Externí odkaz:
https://doaj.org/article/07d99d58976b4e01996ddce1ebeeb842
Publikováno v:
Applied Sciences, Vol 13, Iss 18, p 10493 (2023)
Fine-grained image recognition aims to classify fine subcategories belonging to the same parent category, such as vehicle model or bird species classification. This is an inherently challenging task because a classifier must capture subtle interclass
Externí odkaz:
https://doaj.org/article/d574cfaf6a0d48be9cd0283988b2d6ad
Autor:
Eunkyung Lie, Yeji Yeo, Eun-Jae Lee, Wangyong Shin, Kyungdeok Kim, Kyung Ah Han, Esther Yang, Tae-Yong Choi, Mihyun Bae, Suho Lee, Seung Min Um, Se-Young Choi, Hyun Kim, Jaewon Ko, Eunjoon Kim
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
To elucidate the role of synaptic cell adhesion-like molecule 4 (SALM4) in altering synaptic function in the context of fear memory, Lie at al performed behavioural and electrophysiological assessments of SALM4 knockout mice undergoing cued fear, spa
Externí odkaz:
https://doaj.org/article/9c6821f43b5b415bb8a595e34ac8759f
Autor:
Eunee Lee, Seungjoon Lee, Jae Jin Shin, Woochul Choi, Changuk Chung, Suho Lee, Jihye Kim, Seungmin Ha, Ryunhee Kim, Taesun Yoo, Ye-Eun Yoo, Jisoo Kim, Young Woo Noh, Issac Rhim, Soo Yeon Lee, Woohyun Kim, Taekyung Lee, Hyogeun Shin, Il-Joo Cho, Karl Deisseroth, Sang Jeong Kim, Joo Min Park, Min Whan Jung, Se-Bum Paik, Eunjoon Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
How NMDAR and GABA neuronal dysfunctions result in impaired social behaviour is unclear. Here, the authors show that NMDARs and gap junctions in cortical PV interneurons modulate burst firing, affecting social behaviour.
Externí odkaz:
https://doaj.org/article/be579d8154684279867ebaa15847607e