Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Suhas G. Kallapur"'
Autor:
Pietro Presicce, Cynthia Roland, Paranthaman Senthamaraikannan, Monica Cappelletti, McKensie Hammons, Lisa A. Miller, Alan H. Jobe, Claire A. Chougnet, Emily DeFranco, Suhas G. Kallapur
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIL6 signaling plays an important role in triggering labor and IL6 is an established biomarker of intrauterine infection/inflammation (IUI) driven preterm labor (PTL). The biology of IL6 during IUI at the maternal-fetal interface was inves
Externí odkaz:
https://doaj.org/article/922d9b5b34804f2f99ba4aa1523324fc
Autor:
Monica Cappelletti, Daniel Short, Marco Morselli, Matteo Pellegrini, Mark R. Johnson, Yalda Afshar, Suhas G. Kallapur, Pietro Presicce
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103044- (2024)
Summary: The amnion is a thin layer of fetal origin in contact with the amniotic fluid which plays a key role at the feto-maternal interface during pregnancy. Here, we present a protocol for isolation of human and Rhesus macaque amnion cells. We desc
Externí odkaz:
https://doaj.org/article/082003189499455281f58448a4a6d029
Autor:
Josef Newman, Xiaoying Tong, April Tan, Toni Yeasky, Vanessa Nunes De Paiva, Pietro Presicce, Paranthaman S. Kannan, Kevin Williams, Andreas Damianos, Marione Tamase Newsam, Merline K. Benny, Shu Wu, Karen C. Young, Lisa A. Miller, Suhas G. Kallapur, Claire A. Chougnet, Alan H. Jobe, Roberta Brambilla, Augusto F. Schmidt
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Preterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism. Preterm birth can lead to cerebellar underdevelopment, but the mechanisms of disrupted cerebellar
Externí odkaz:
https://doaj.org/article/4330d26737704358ad8660367418ee35
Autor:
Pietro Presicce, Monica Cappelletti, Marco Morselli, Feiyang Ma, Paranthaman Senthamaraikannan, Giulia Protti, Brian B. Nadel, Laila Aryan, Mansoureh Eghbali, Lukasz Salwinski, Neema Pithia, Emily De Franco, Lisa A. Miller, Matteo Pellegrini, Alan H. Jobe, Claire A. Chougnet, Suhas G. Kallapur
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108118- (2023)
Summary: Intrauterine infection/inflammation (IUI) is a frequent complication of pregnancy leading to preterm labor and fetal inflammation. How inflammation is modulated at the maternal-fetal interface is unresolved. We compared transcriptomics of am
Externí odkaz:
https://doaj.org/article/77d0fd7b7d1341148a8871c73ddb3327
Autor:
Julia Heiter, Matthew W. Kemp, Owen B. Spiller, Dominique Singer, John P. Newnham, Suhas G. Kallapur, Alan H. Jobe, Boris W. Kramer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChorioamnionitis is common in preterm birth and associated with a higher risk of intestinal inflammation and necrotizing enterocolitis. The intestinal inflammation influences the enteric nervous system development. We hypothesized that in
Externí odkaz:
https://doaj.org/article/78bc20f8aaed45399ad47bc2e04ea5b8
Autor:
Anela Tosevska, Shubhamoy Ghosh, Amit Ganguly, Monica Cappelletti, Suhas G. Kallapur, Matteo Pellegrini, Sherin U. Devaskar
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The placenta is a heterogeneous organ whose development involves complex interactions of trophoblasts with decidual, vascular, and immune cells at the fetal–maternal interface. It maintains a critical balance between maternal and fetal hom
Externí odkaz:
https://doaj.org/article/fa4e524a4f664b6789e079ddc4dccdca
Autor:
Jessica R. Doll, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Jennifer L. Wayland, Adrienne Wilburn, Benjamin Weinhaus, Claire A. Chougnet, Daniela Giordano, Monica Cappelletti, Pietro Presicce, Suhas G. Kallapur, Nathan Salomonis, Tamara Tilburgs, Senad Divanovic
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112352- (2023)
Summary: Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF pro
Externí odkaz:
https://doaj.org/article/59d828a84fe34ca5847dca21b989426e
Autor:
Heather M. Brockway, Samantha L. Wilson, Suhas G. Kallapur, Catalin S. Buhimschi, Louis J. Muglia, Helen N. Jones
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Preterm birth is a global public health crisis which results in significant neonatal and maternal mortality. Yet little is known regarding the molecular mechanisms of idiopathic spontaneous preterm birth, and we have few diagnostic markers for adequa
Externí odkaz:
https://doaj.org/article/5d1a23f1e0fd4f0ebd1b8b82572f7ca0
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pro-inflammatory cytokine that is increased in the amniotic fluid in chorioamnionitis and elevated in the fetal lung with endotoxin exposure. Although GM-CSF has a pivotal rol
Externí odkaz:
https://doaj.org/article/5df94bb16dc34ee68a0f94ac5a264faf
Autor:
Augusto F. Schmidt, Paranthaman S. Kannan, James Bridges, Pietro Presicce, Courtney M. Jackson, Lisa A. Miller, Suhas G. Kallapur, Claire A. Chougnet, Alan H. Jobe
Publikováno v:
JCI Insight, Vol 5, Iss 24 (2021)
Respiratory complications are the major cause of morbidity and mortality among preterm infants, which is partially prevented by the administration of antenatal corticosteroids (ACS). Most very preterm infants are exposed to chorioamnionitis, but shor
Externí odkaz:
https://doaj.org/article/dfafcfd0ceb94a87a1c8721b2ece4cdb