Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Suhas, Vasaikar"'
Autor:
Raksha Bhat, Hariprasad Thangavel, Noor Mazin Abdulkareem, Suhas Vasaikar, Carmine De Angelis, Leon Bae, Maria Letizia Cataldo, Sarmistha Nanda, Xiaoyong Fu, Bing Zhang, Rachel Schiff, Meghana V. Trivedi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract G Protein-Coupled Receptors (GPCRs) represent the largest superfamily of cell-surface proteins. However, the expression and function of majority of GPCRs remain unexplored in breast cancer (BC). We interrogated the expression and phosphoryla
Externí odkaz:
https://doaj.org/article/f573b7bda516414bb4b2dfb6151cfce9
Autor:
Varduhi Petrosyan, Lacey E. Dobrolecki, Lillian Thistlethwaite, Alaina N. Lewis, Christina Sallas, Ramakrishnan R. Srinivasan, Jonathan T. Lei, Vladimir Kovacevic, Predrag Obradovic, Matthew J. Ellis, C. Kent Osborne, Mothaffar F. Rimawi, Anne Pavlick, Maryam Nemati Shafaee, Heidi Dowst, Antrix Jain, Alexander B. Saltzman, Anna Malovannaya, Elisabetta Marangoni, Alana L. Welm, Bryan E. Welm, Shunqiang Li, Gerburg M. Wulf, Olmo Sonzogni, Chen Huang, Suhas Vasaikar, Susan G. Hilsenbeck, Bing Zhang, Aleksandar Milosavljevic, Michael T. Lewis
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105799- (2023)
Summary: Although systemic chemotherapy remains the standard of care for TNBC, even combination chemotherapy is often ineffective. The identification of biomarkers for differential chemotherapy response would allow for the selection of responsive pat
Externí odkaz:
https://doaj.org/article/2b0f86504c374089a6c4e5c09a09e1cb
Publikováno v:
BMC Bioinformatics, Vol 19, Iss S17, Pp 29-37 (2018)
Abstract Background Due to recent technology advancements, disease related knowledge is growing rapidly. It becomes nontrivial to go through all published literature to identify associations between human diseases and genetic, environmental, and life
Externí odkaz:
https://doaj.org/article/1f4787cc503244609809889971199e9a
Autor:
Jonathan T. Lei, Chen Huang, Ramakrishnan R. Srinivasan, Suhas Vasaikar, Lacey E. Dobrolecki, Alaina N. Lewis, Na Zhao, Jin Cao, Susan G. Hilsenbeck, C. Kent Osborne, Mothaffar Rimawi, Matthew J. Ellis, Varduhi Petrosyan, Alexander B. Saltzman, Anna Malovannaya, John D. Landua, Bo Wen, Antrix Jain, Gerburg M. Wulf, Shunqiang Li, Daniel C. Kraushaar, Tao Wang, Xi Chen, Gloria V. Echeverria, Meenakshi Anurag, Bing Zhang, Michael T. Lewis
Publikováno v:
Cancer Research. 83:P2-23
Background: Triple-negative breast cancer (TNBC) patients frequently receive combination chemotherapy treatment, but a direct comparison of response to carboplatin, docetaxel, and their combination in 50 TNBC patient-derived xenografts (PDXs) showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5115ca00f0415091ae7a90683abd9716
https://doi.org/10.1158/1538-7445.sabcs22-p2-23-01
https://doi.org/10.1158/1538-7445.sabcs22-p2-23-01
Overexpression of endothelin B receptor in glioblastoma: a prognostic marker and therapeutic target?
Autor:
Suhas Vasaikar, Giorgos Tsipras, Natalia Landázuri, Helena Costa, Vanessa Wilhelmi, Patrick Scicluna, Huanhuan L. Cui, Abdul-Aleem Mohammad, Belghis Davoudi, Mingmei Shang, Sharan Ananthaseshan, Klas Strååt, Giuseppe Stragliotto, Afsar Rahbar, Kum Thong Wong, Jesper Tegner, Koon-Chu Yaiw, Cecilia Söderberg-Naucler
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Glioblastoma (GBM) is the most common malignant brain tumor with median survival of 12-15 months. Owing to uncertainty in clinical outcome, additional prognostic marker(s) apart from existing markers are needed. Since overexpressi
Externí odkaz:
https://doaj.org/article/eb7a314e54f24c7e91cc8421104d2f9d
Autor:
Eva González-Suárez, Xose S. Puente, Michael T. Lewis, Miguel Angel Pujana, Violeta Serra, Cristina Cruz, Judith Balmaña, Anna Petit, María Teresa Soler-Monso, Joaquín Arribas, Carlos Caldas, Alejandra Bruna, Aleix Prat, Laia Paré, Purificación Muñoz, Eva M. Trinidad, Alejandro Collado-Sole, Gerburg M. Wulf, Bing Zhang, Suhas Vasaikar, Chen Huang, Lacey E. Dobrolecki, Marta Palafox, Luis Palomero, Sergi Beltran, Raul Tonda, Ander Díaz-Navarro, Jorge Gómez-Miragaya
Supplementary methods and legends for supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c459f478caf89ee13f2a4d0789fe97
https://doi.org/10.1158/0008-5472.22421748.v1
https://doi.org/10.1158/0008-5472.22421748.v1
Autor:
Eva González-Suárez, Xose S. Puente, Michael T. Lewis, Miguel Angel Pujana, Violeta Serra, Cristina Cruz, Judith Balmaña, Anna Petit, María Teresa Soler-Monso, Joaquín Arribas, Carlos Caldas, Alejandra Bruna, Aleix Prat, Laia Paré, Purificación Muñoz, Eva M. Trinidad, Alejandro Collado-Sole, Gerburg M. Wulf, Bing Zhang, Suhas Vasaikar, Chen Huang, Lacey E. Dobrolecki, Marta Palafox, Luis Palomero, Sergi Beltran, Raul Tonda, Ander Díaz-Navarro, Jorge Gómez-Miragaya
Docetaxel response on TNBC cell lines with ETV6 and GABARAPL1 overexpression and knockdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8c8345a1ddeb9a7b70d6b65550935a
https://doi.org/10.1158/0008-5472.22421757
https://doi.org/10.1158/0008-5472.22421757
Autor:
Eva González-Suárez, Xose S. Puente, Michael T. Lewis, Miguel Angel Pujana, Violeta Serra, Cristina Cruz, Judith Balmaña, Anna Petit, María Teresa Soler-Monso, Joaquín Arribas, Carlos Caldas, Alejandra Bruna, Aleix Prat, Laia Paré, Purificación Muñoz, Eva M. Trinidad, Alejandro Collado-Sole, Gerburg M. Wulf, Bing Zhang, Suhas Vasaikar, Chen Huang, Lacey E. Dobrolecki, Marta Palafox, Luis Palomero, Sergi Beltran, Raul Tonda, Ander Díaz-Navarro, Jorge Gómez-Miragaya
Taxanes are the mainstay of treatment in triple-negative breast cancer (TNBC), with de novo and acquired resistance limiting patient's survival. To investigate the genetic basis of docetaxel resistance in TNBC, exome sequencing was performed on match
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98573ba4edc3d2e2455e34f8453a5f5e
https://doi.org/10.1158/0008-5472.c.6511020
https://doi.org/10.1158/0008-5472.c.6511020
Autor:
Eva González-Suárez, Xose S. Puente, Michael T. Lewis, Miguel Angel Pujana, Violeta Serra, Cristina Cruz, Judith Balmaña, Anna Petit, María Teresa Soler-Monso, Joaquín Arribas, Carlos Caldas, Alejandra Bruna, Aleix Prat, Laia Paré, Purificación Muñoz, Eva M. Trinidad, Alejandro Collado-Sole, Gerburg M. Wulf, Bing Zhang, Suhas Vasaikar, Chen Huang, Lacey E. Dobrolecki, Marta Palafox, Luis Palomero, Sergi Beltran, Raul Tonda, Ander Díaz-Navarro, Jorge Gómez-Miragaya
Supplementary Table S1. Models, point mutations and CNA Supplementary Table S2. Differentially expressed genes, pathways and co-occurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9c874c83d95ae28fdf557fd4a36fd4
https://doi.org/10.1158/0008-5472.22421751
https://doi.org/10.1158/0008-5472.22421751
Autor:
Jonathan T Lei, Chen Huang, Ramakrishnan R Srinivasan, Suhas Vasaikar, Lacey E Dobrolecki, Alaina N Lewis, Christina Sallas, Susan G Hilsenbeck, C. Kent Osborne, Mothaffar F Rimawi, Matthew J Ellis, Varduhi Petrosyan, Alexander B Saltzman, Anna Malovannaya, Gerburg Wulf, Daniel C Kraushaar, Tao Wang, Xi Chen, Gloria V Echeverria, Meenakshi Anurag, Bing Zhang, Michael T Lewis
Publikováno v:
Cancer Research. 82:P5-07
Background: Chemotherapy is essential for the management of patients with triple-negative breast cancer (TNBC). Identification of biomarkers that may indicate treatment efficacy will be critical to improve patient stratification prior to treatment. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0f7353849cf17b6035b7c0b28f5209
https://doi.org/10.1158/1538-7445.sabcs21-p5-07-01
https://doi.org/10.1158/1538-7445.sabcs21-p5-07-01