Evaluation of toxicity profile of kratom (Mitragyna speciosa Korth) decoction in rats.

Autor: Hassan Z; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia. Electronic address: zurina_hassan@usm.my., Singh D; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Suhaimi FW; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Chear NJ; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Harun N; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., See CP; Department of Human Anatomy, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia., Kaur G; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800, USM, Penang, Malaysia., Mat NH; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Bakar SNS; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Yusof NSM; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Kasinather VB; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia., Chawarski MC; Departments of Psychiatry and Emergency Medicine, Yale School of Medicine, New Haven, CT, USA., Murugaiyah V; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia; Discipline of Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia., Ramanathan S; Centre for Drug Research, Universiti Sains Malaysia, 11800, Penang, Malaysia.

Publikováno v: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2023 Sep; Vol. 143, pp. 105466. Date of Electronic Publication: 2023 Aug 01.

Kratom (M. speciosa) exposure during adolescence caused long-lasting cognitive behavioural deficits associated with perturbated brain metabolism pathways in adult rats.

Autor: Suhaimi FW; Centre for Drug Research, Universiti Sains Malaysia, Pulau Pinang, Malaysia. Electronic address: sfarahwahida@usm.my., Zul Aznal AN; Centre for Drug Research, Universiti Sains Malaysia, Pulau Pinang, Malaysia., Mohamad Nor Hazalin NA; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA, Cawangan Selangor, Kampus Puncak Alam, Malaysia., Teh LK; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA, Cawangan Selangor, Kampus Puncak Alam, Malaysia., Hassan Z; Centre for Drug Research, Universiti Sains Malaysia, Pulau Pinang, Malaysia., Salleh MZ; Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA, Cawangan Selangor, Kampus Puncak Alam, Malaysia.

Publikováno v: Behavioural brain research [Behav Brain Res] 2023 May 28; Vol. 446, pp. 114411. Date of Electronic Publication: 2023 Mar 28.

Mitragynine improves cognitive performance in morphine-withdrawn rats.

Autor: You CY; Centre for Drug Research, Universiti Sains Malaysia, Minden, Penang, Malaysia., Hassan Z; Centre for Drug Research, Universiti Sains Malaysia, Minden, Penang, Malaysia., Müller CP; Centre for Drug Research, Universiti Sains Malaysia, Minden, Penang, Malaysia.; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, Erlangen, Germany., Suhaimi FW; Centre for Drug Research, Universiti Sains Malaysia, Minden, Penang, Malaysia. sfarahwahida@usm.my.

Publikováno v: Psychopharmacology [Psychopharmacology (Berl)] 2022 Jan; Vol. 239 (1), pp. 313-325. Date of Electronic Publication: 2021 Oct 25.

Mitragynine (Kratom) impairs spatial learning and hippocampal synaptic transmission in rats.

Autor: Hassan Z; 1 Centre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia., Suhaimi FW; 1 Centre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia., Ramanathan S; 1 Centre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia., Ling KH; 2 Department of Biomedical Science, Universiti Putra Malaysia, Selangor, Malaysia., Effendy MA; 1 Centre for Drug Research, Universiti Sains Malaysia, Penang, Malaysia., Müller CP; 3 Department of Psychiatry and Psychotherapy, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany., Dringenberg HC; 4 Department of Psychology and Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.

Publikováno v: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2019 Jul; Vol. 33 (7), pp. 908-918. Date of Electronic Publication: 2019 May 13.

Abuse potential and adverse cognitive effects of mitragynine (kratom).

Autor: Yusoff NH; Centre for Drug Research, Universiti Sains Malaysia, Malaysia., Suhaimi FW; Centre for Drug Research, Universiti Sains Malaysia, Malaysia., Vadivelu RK; Centre for Drug Research, Universiti Sains Malaysia, Malaysia.; Eskitis Institute for Drug Discovery, Griffith University, Australia., Hassan Z; Centre for Drug Research, Universiti Sains Malaysia, Malaysia., Rümler A; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University Erlangen-Nuremberg, Germany., Rotter A; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University Erlangen-Nuremberg, Germany., Amato D; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University Erlangen-Nuremberg, Germany., Dringenberg HC; Department of Psychology and Centre for Neuroscience Studies, Queen's University, Canada., Mansor SM; Centre for Drug Research, Universiti Sains Malaysia, Malaysia., Navaratnam V; Centre for Drug Research, Universiti Sains Malaysia, Malaysia., Müller CP; Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University Erlangen-Nuremberg, Germany.

Publikováno v: Addiction biology [Addict Biol] 2016 Jan; Vol. 21 (1), pp. 98-110. Date of Electronic Publication: 2014 Sep 28.