Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Suhaib H. Abudulwahed"'
Autor:
Ning Li, Anuradha Kalyanasundaram, Brian J. Hansen, Esthela J. Artiga, Roshan Sharma, Suhaib H. Abudulwahed, Katelynn M. Helfrich, Galina Rozenberg, Pei-Jung Wu, Stanislav Zakharkin, Sandor Gyorke, Paul ML. Janssen, Bryan A. Whitson, Nahush A. Mokadam, Brandon J. Biesiadecki, Federica Accornero, John D. Hummel, Peter J. Mohler, Halina Dobrzynski, Jichao Zhao, Vadim V. Fedorov
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The role of of voltage-gated sodium channels (Nav) in pacemaking and conduction of the human sinoatrial node is unclear. Here, the authors investigate existence and function of neuronal and cardiac Nav in human sinoatrial nodes, and demonstrate their
Externí odkaz:
https://doaj.org/article/f630452532e74b488261b252cd5af083
Autor:
Vadim V. Fedorov, Jichao Zhao, Ning Li, Brian J. Hansen, Peter J. Mohler, Sándor Györke, Roshan Sharma, Galina Rozenberg, Paul M.L. Janssen, Katelynn M. Helfrich, Stanislav O. Zakharkin, Bryan A. Whitson, Halina Dobrzynski, Pei Jung Wu, Anuradha Kalyanasundaram, Suhaib H. Abudulwahed, Esthela J. Artiga, John D. Hummel, Federica Accornero, Brandon J. Biesiadecki, Nahush A. Mokadam
Publikováno v:
Li, N, Kalyanasundaram, A, Hansen, B J, Artiga, E J, Sharma, R, Abudulwahed, S H, Helfrich, K M, Rozenberg, G, Wu, P-J, Zakharkin, S, Gyorke, S, Janssen, P, Whitson, B A, Mokadam, N A, Biesiadecki, B J, Accornero, F, Hummel, J D, Jichao Zhao, J, Mohler, P J, Dobrzynski, H & Fedorov, V V 2020, ' Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node ', Nature Communications, vol. 11, no. 1, 512, pp. 512 . https://doi.org/10.1038/s41467-019-14039-8
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Mechanisms for human sinoatrial node (SAN) dysfunction are poorly understood and whether human SAN excitability requires voltage-gated sodium channels (Nav) remains controversial. Here, we report that neuronal (n)Nav blockade and selective nNav1.6 bl
Autor:
Matthew E. Joseph, Suhaib H. Abudulwahed, Vadim V. Fedorov, John D. Hummel, Peter J. Mohler, Brian J. Hansen, Esthela J. Artiga, Ning Li, Katelynn M. Helfrich
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 11
Autor:
Jichao Zhao, Peter J. Mohler, Anna Bratasz, Josh Atwal, Paul M.L. Janssen, Yufeng Wang, Ning Li, Vadim V. Fedorov, John D. Hummel, Katelynn M. Helfrich, Bryan A. Whitson, Orlando P. Simonetti, Kimerly A. Powell, Suhaib H. Abudulwahed, Anuradha Kalyanasundaram, Stanislav O. Zakharkin, Brian J. Hansen, Alexander M. Zolotarev
Publikováno v:
JACC. Clinical electrophysiology. 4(12)
BACKGROUND: Clinical multi-electrode mapping of atrial fibrillation (AF) drivers suffers from variable contact, signal processing, and structural complexity within the 3D human atrial wall, raising questions on the validity of such drivers. OBJECTIVE