Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Suhad Al-Yahya"'
Autor:
Minjing Zou, Suhad Al-Yahya, Monther Al-Alwan, Huda A. BinEssa, Khalid S. A. Khabar, Falah Almohanna, Abdullah M. Assiri, Abdulmohsen Altaweel, Amal Qattan, Brian F. Meyer, Ali S. Alzahrani, Yufei Shi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionBRAFV600E mutations frequently occur in papillary thyroid cancer (PTC). β-catenin, encoded by CTNNB1, is a key downstream component of the canonical Wnt signaling pathway and is often overexpressed in PTC. BRAFV600E-driven PTC tumors rel
Externí odkaz:
https://doaj.org/article/04631e41d80f49b3a9a9b059ef74c4bf
Autor:
Qamraa H. Al‐Qahtani, Walid N. Moghrabi, Suhad Al‐Yahya, Latifa Al‐Haj, Maher Al‐Saif, Linah Mahmoud, Falah Al‐Mohanna, Norah Al‐Souhibani, Ayodele Alaiya, Edward Hitti, Khalid S. A. Khabar
Publikováno v:
Molecular Oncology, Vol 15, Iss 8, Pp 2120-2139 (2021)
Dysfunctions in post‐transcriptional control are observed in cancer and chronic inflammatory diseases. Here, we employed a kinome inhibitor library (n = 378) in a reporter system selective for 3′‐untranslated region–AU‐rich elements (ARE).
Externí odkaz:
https://doaj.org/article/9b16b262c2074fbf8d05f478d8b4d7df
Autor:
Yufei Shi, Futwan A. Al-Mohanna, Ali S. Alzahrani, Brian F. Meyer, Abdullah M. Assiri, Falah Almohanna, Khalid S.A. Khabar, Ibrahim Al-Jammaz, Monther Al-Alwan, Suhad Al-Yahya, Yousif H. Al-Malki, Huda A. BinEssa, Minjing Zou
Fig. S1. Up-regulation of thyroid hormone synthesis-related genes in the BVE-Ctnnb1null thyroid tumors. Data are expressed as fold changes between BVE-Ctnnb1null and BVE tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043c3fc3e82e43654a919e52983983da
https://doi.org/10.1158/1535-7163.22521871.v1
https://doi.org/10.1158/1535-7163.22521871.v1
Autor:
Yufei Shi, Futwan A. Al-Mohanna, Ali S. Alzahrani, Brian F. Meyer, Abdullah M. Assiri, Falah Almohanna, Khalid S.A. Khabar, Ibrahim Al-Jammaz, Monther Al-Alwan, Suhad Al-Yahya, Yousif H. Al-Malki, Huda A. BinEssa, Minjing Zou
BRAFV600E mutation is the most frequent genetic alteration in papillary thyroid cancer (PTC). β-Catenin (Ctnnb1) is a key downstream component of canonical Wnt signaling pathway and is frequently overexpressed in PTC. BRAFV600E-driven tumors have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190cd776a9698e2d2e090166b68c8ccd
https://doi.org/10.1158/1535-7163.c.6543208
https://doi.org/10.1158/1535-7163.c.6543208
Autor:
Khalid S.A. Khabar, Gilles Pagès, Balázs Győrffy, Renaud Grépin, András Lánczky, Mohamed M. Shoukri, Maher Al-Saif, Maha Al-Ghamdi, Suhad Al-Yahya, Walid Moghrabi, Norah Al-Souhibani, Tala Bakheet, Edward Hitti
Overall list the over-expressed ARE-mRNAs in breast cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ccd07a744646eb0ff8c95a819165fc
https://doi.org/10.1158/0008-5472.22412201
https://doi.org/10.1158/0008-5472.22412201
Autor:
Khalid S.A. Khabar, Gilles Pagès, Balázs Győrffy, Renaud Grépin, András Lánczky, Mohamed M. Shoukri, Maher Al-Saif, Maha Al-Ghamdi, Suhad Al-Yahya, Walid Moghrabi, Norah Al-Souhibani, Tala Bakheet, Edward Hitti
Defects in AU-rich elements (ARE)-mediated posttranscriptional control can lead to several abnormal processes that underlie carcinogenesis. Here, we performed a systematic analysis of ARE-mRNA expression across multiple cancer types. First, the ARE d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3758d6f1d8fd764eec01a63f69178e40
https://doi.org/10.1158/0008-5472.c.6508388.v1
https://doi.org/10.1158/0008-5472.c.6508388.v1
Autor:
Khalid S.A. Khabar, Gilles Pagès, Balázs Győrffy, Renaud Grépin, András Lánczky, Mohamed M. Shoukri, Maher Al-Saif, Maha Al-Ghamdi, Suhad Al-Yahya, Walid Moghrabi, Norah Al-Souhibani, Tala Bakheet, Edward Hitti
Supplemental methods on statistical correlation modeling, RNA-IP, and Taqman assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588b9c1555826e077b1fc51ec4f6861f
https://doi.org/10.1158/0008-5472.22412210
https://doi.org/10.1158/0008-5472.22412210
Autor:
Khalid S.A. Khabar, Gilles Pagès, Balázs Győrffy, Renaud Grépin, András Lánczky, Mohamed M. Shoukri, Maher Al-Saif, Maha Al-Ghamdi, Suhad Al-Yahya, Walid Moghrabi, Norah Al-Souhibani, Tala Bakheet, Edward Hitti
Correlation data of the mRNA levels for TTP, HuR, TTP/HuR ratio with ARE- and non-ARE mRNA expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283688b3c9ecc580eca972d6f1b4cafb
https://doi.org/10.1158/0008-5472.22412198.v1
https://doi.org/10.1158/0008-5472.22412198.v1
Autor:
Khalid S.A. Khabar, Gilles Pagès, Balázs Győrffy, Renaud Grépin, András Lánczky, Mohamed M. Shoukri, Maher Al-Saif, Maha Al-Ghamdi, Suhad Al-Yahya, Walid Moghrabi, Norah Al-Souhibani, Tala Bakheet, Edward Hitti
Reporter sequences containing the putative AREs and their AU context
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a342211ab840e2cf9c133e3dd78e5110
https://doi.org/10.1158/0008-5472.22412195
https://doi.org/10.1158/0008-5472.22412195
Autor:
Ayodele Alaiya, Norah Al-Souhibani, Latifa Al-Haj, Qamraa H. Al‐Qahtani, Falah Al-Mohanna, Edward Hitti, Suhad Al-Yahya, Walid Moghrabi, Maher Al-Saif, Khalid S.A. Khabar, Linah Mahmoud
Publikováno v:
Molecular Oncology, Vol 15, Iss 8, Pp 2120-2139 (2021)
Molecular Oncology
Molecular Oncology
Dysfunctions in post‐transcriptional control are observed in cancer and chronic inflammatory diseases. Here, we employed a kinome inhibitor library (n = 378) in a reporter system selective for 3′‐untranslated region–AU‐rich elements (ARE).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db036870787f3266b37aae25edb28f2
https://doaj.org/article/9b16b262c2074fbf8d05f478d8b4d7df
https://doaj.org/article/9b16b262c2074fbf8d05f478d8b4d7df