Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Suhad A.A. Al-Salihi"'
Publikováno v:
Molecular Biotechnology
Al-Salihi, S A A, Dao, T T, Williams, K, Bailey, A M & Foster, G D 2019, ' The Biogenetic Origin of the Biologically Active Naematolin of Hypholoma Species Involves an Unusual Sesquiterpene Synthase ', Molecular Biotechnology, vol. 61, no. 10, pp. 754-762 . https://doi.org/10.1007/s12033-019-00199-x
Al-Salihi, S A A, Dao, T T, Williams, K, Bailey, A M & Foster, G D 2019, ' The Biogenetic Origin of the Biologically Active Naematolin of Hypholoma Species Involves an Unusual Sesquiterpene Synthase ', Molecular Biotechnology, vol. 61, no. 10, pp. 754-762 . https://doi.org/10.1007/s12033-019-00199-x
Naematolin is a biologically active sesquiterpene produced by Hypholoma species. Low titres and complex structure constrain the exploitation of this secondary metabolite. Here, we de novo sequenced the H. fasciculare genome to identify a candidate bi
Further Biochemical Profiling of Hypholoma fasciculare Metabolome Reveals Its Chemogenetic Diversity
Autor:
Andy M. Bailey, Ian D. Bull, Paul J. Gates, Kifah S. M. Salih, Gary D. Foster, Suhad A.A. Al-Salihi, Raghad A. Al-Salhi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Al-Salihi, S A A, Bull, I D, Al-Salhi, R A, Gates, P J, Salih, K S M, Bailey, A M & Foster, G D 2021, ' Further biochemical profiling of Hypholoma fasciculare metabolome reveals its chemo-genetic diversity ', Frontiers in Bioengineering and Biotechnology, vol. 9, 567384 . https://doi.org/10.3389/fbioe.2021.567384
Al-Salihi, S A A, Bull, I D, Al-Salhi, R A, Gates, P J, Salih, K S M, Bailey, A M & Foster, G D 2021, ' Further biochemical profiling of Hypholoma fasciculare metabolome reveals its chemo-genetic diversity ', Frontiers in Bioengineering and Biotechnology, vol. 9, 567384 . https://doi.org/10.3389/fbioe.2021.567384
There is a desperate need in continuing the search for natural products with novel mechanism to battle the constant increase of microbial drug resistance. Previously mushroom forming fungi were neglected as a source of novel antibiotics, due to the d
Publikováno v:
Al-Salihi, S A A, Scott, T A, Bailey, A M & Foster, G D 2017, ' Improved vectors for Agrobacterium mediated genetic manipulation of Hypholoma spp. and other homobasidiomycetes ', Journal of Microbiological Methods, vol. 142, pp. 4-9 . https://doi.org/10.1016/j.mimet.2017.08.014
The basidiomycete fungi Hypholoma fasciculare and H. sublateritium are both prolific producers of sesquiterpenes and triterpenes, some of which have relevant pharmaceutical properties. Although H. sublateritium has been transformed in the past, the l