Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Suh-Chin J. Lin"'
Autor:
Kelly M. Grimes, Vikram Prasad, Jiuzhou Huo, Yasuhide Kuwabara, Davy Vanhoutte, Tanya A. Baldwin, Stephanie L. K. Bowers, Anne Katrine Z. Johansen, Michelle A. Sargent, Suh-Chin J. Lin, Jeffery D. Molkentin
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: The ribosomal protein L3-like (RPL3L) is a heart and skeletal muscle-specific ribosomal protein and paralogue of the more ubiquitously expressed RPL3 protein. Mutations in the human RPL3L gene are linked to childhood cardiomyopathy and
Externí odkaz:
https://doaj.org/article/e9e91a84e9de42468035dd74dbc281e1
Autor:
Onur Kanisicak, Hadi Khalil, Malina J. Ivey, Jason Karch, Bryan D. Maliken, Robert N. Correll, Matthew J. Brody, Suh-Chin J. Lin, Bruce J. Aronow, Michelle D. Tallquist, Jeffery D. Molkentin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The origin and fate of myofibroblasts, the cells responsible for cardiac remodelling and fibrosis, is controversial. Here the authors show that cardiac myofibroblasts express periostin, derive exclusively from tissue-resident fibroblasts, are necessa
Externí odkaz:
https://doaj.org/article/2d97317374d240aba3646b2db0044a01
Autor:
Charles E. Murry, Ronald J. Vagnozzi, Suh-Chin J. Lin, Michelle A. Sargent, Nathan J. Palpant, Jeffery D. Molkentin
Publikováno v:
Circulation. 138:2931-2939
Background: The adult mammalian heart displays a cardiomyocyte turnover rate of ≈1%/y throughout postnatal life and after injuries such as myocardial infarction (MI), but the question of which cell types drive this low level of new cardiomyocyte fo
Autor:
Matthew J. Brody, Jason Karch, Onur Kanisicak, Malina J. Ivey, Bruce J. Aronow, Robert N. Correll, Jeffery D. Molkentin, Hadi Khalil, Bryan D. Maliken, Suh-Chin J. Lin, Michelle D. Tallquist
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications
Nature communication
Nature Communications
Nature communication
Cardiac fibroblasts convert to myofibroblasts with injury to mediate healing after acute myocardial infarction (MI) and to mediate long-standing fibrosis with chronic disease. Myofibroblasts remain a poorly defined cell type in terms of their origins
Autor:
Onur Kanisicak, Andoria Tjondrokoesoemo, Vikram Prasad, Marjorie Maillet, Suh-Chin J. Lin, Davy Vanhoutte, Jeffery D. Molkentin, Michelle A. Sargent, Tobias G. Schips
Duchenne muscular dystrophy (DMD) is an X-linked recessive disease caused by mutations in the gene encoding dystrophin. Loss of dystrophin protein compromises the stability of the sarcolemma membrane surrounding each muscle cell fiber, leading to mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540da20f415a8297f6d589c09a4cb885
https://europepmc.org/articles/PMC4858995/
https://europepmc.org/articles/PMC4858995/
Autor:
Jason Karch, Ryan Middleton, Onur Kanisicak, Jeffery D. Molkentin, Eduardo Marbán, Ronald J. Vagnozzi, Suh Chin J. Lin, Marjorie Maillet, Jop H. van Berlo
Publikováno v:
Nature. 555:E18-E18
Autor:
Andrew M. Lowy, James M. Wells, Injune Kim, Jeffrey A. Whitsett, Suh Chin J. Lin, Klaus H. Kaestner, Jason R. Spence, Alexander W. Lange
Publikováno v:
Developmental Cell. 17:62-74
SummaryThe ventral pancreas, biliary system, and liver arise from the posterior ventral foregut, but the cell-intrinsic pathway by which these organ lineages are separated is not known. Here we show that the extrahepatobiliary system shares a common
Autor:
Natasha Ghearing, Jeffery D. Molkentin, Suh-Chin J. Lin, Jennifer Davis, Nathan Salomonis, Maurice S. Swanson, Apoorva Mohan, Jennifer Q. Kwong
Publikováno v:
Nature Communications
The differentiation of fibroblasts into myofibroblasts mediates tissue wound healing and fibrotic remodelling, although the molecular programme underlying this process remains poorly understood. Here we perform a genome-wide screen for genes that con
Autor:
Jason Karch, Eduardo Marbán, Ryan Middleton, Jop H. van Berlo, Jeffery D. Molkentin, Onur Kanisicak, Suh Chin J. Lin, Ronald J. Vagnozzi, Marjorie Maillet
Publikováno v:
Nature. 509(7500)
If and how the heart regenerates after an injury event is highly debated. c-kit-expressing cardiac progenitor cells have been reported as the primary source for generation of new myocardium after injury. Here we generated two genetic approaches in mi
Autor:
Małgorzata Z. Zdzienicka, Suh-Chin J. Lin, Yosef Shiloh, Song Zhao, Jerry W. Shay, Yael Ziv, Eva Y.-H. P. Lee, Mei-hua Song, Yi-Chinn Weng, Elvira Gerbino, Shyng Shiou F Yuan, Richard A. Gatti, Hao-Chi Hsu, Yi-Tzu Lin
Publikováno v:
Nature. 405:473-477
Ataxia-telangiectasia (A-T) and Nijmegen breakage syndrome (NBS) are recessive genetic disorders with susceptibility to cancer and similar cellular phenotypes1. The protein product of the gene responsible for A-T, designated ATM, is a member of a fam